Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$92K - $135K *

Transform sensor chemistry development by leading hands-on experiments, collaborating across teams, and mentoring junior scientists while ensuring regulatory compliance and enhancing product quality i...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $155K *

Join a team that's driving innovation in R&D by managing cross-functional programs aimed at developing transformative gene therapies. You'll oversee project execution, align stakeholders, and enhance...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$140K - $155K *

Oversee program management for R&D initiatives, driving cross-functional team success to ensure timely drug development for therapeutics, particularly in cell and gene therapy using CRISPR technology...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the advancement of a cutting-edge imaging program, overseeing PET/CT and MRI studies. Champion innovative methodologies, foster interdisciplinary collaboration, and drive scientific discovery thr...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$91K - $134K *

Play a key role in advancing Antimicrobial Susceptibility Testing products by designing and executing lab studies, analyzing data, and collaborating with cross-functional teams to enhance product qual...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$91K - $134K *

Join a team that's shaping the future of antimicrobial testing by leveraging your scientific expertise to develop high-quality AST products while collaborating across multidisciplinary teams for impac...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$185K - $225K *

Champion the productization of AutoOpenRaman by establishing system requirements, overseeing mechanical design, and ensuring efficient deployment for scientists in their labs, all while managing proje...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$173K - $237K *

Lead the charge in Clinical Pharmacology, driving innovative strategies and analyses to shape drug development outcomes. Collaborate cross-functionally, ensuring high-quality deliverables for regulato...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$213K - $280K *

Lead LNP formulation and process development efforts, providing strategic direction and scientific expertise across multiple programs while managing a team to ensure high-quality production and operat...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$213K - $280K *

Pioneer LNP formulation and process development strategies, leading and mentoring a team of scientists to drive innovation in small-scale production while collaborating with cross-functional partners...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$127K - $167K *

Support the identification and evaluation of safety data, facilitating signal detection and compliance with regulations while effectively communicating safety assessments to stakeholders. Lead safety...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$79K - $104K *

Unlock your potential by applying innovative technologies in medical products, performing tests, analyzing data, and supporting project teams in a collaborative environment to drive future advancement...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$179K - $246K *

Elevate your career by leading the technical vision for enterprise-wide agentic software engineering practices, making key architectural decisions, mentoring senior engineers, and influencing technica...

3 days ago

  •   11 - 15 years exp.  •   Information Technology

$179K - $246K *

Drive technical innovation and architect enterprise-wide solutions as the senior authority in agentic software engineering, shaping multi-year strategies and mentoring fellow engineers to elevate orga...

4 days ago

  •   11 - 15 years exp.  •   Information Technology

$127K - $195K *

Shape the future of our global services portfolio, leading the charge in validating life-sciences solutions, enhancing customer outcomes while driving strategy and lifecycle decisions that create comp...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $140K *

Join us to ensure compliance and quality in the dynamic world of biopharmaceutical production. Enhance your skills by analyzing critical samples and supporting laboratory operations while adhering to...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's committed to innovation in pharmaceutical formulation and process development. You'll drive hands-on experimentation and scale-up for diverse product lines while collaborating acros...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Oversee advanced sensor systems development from concept to production, leading multidisciplinary teams in aerospace and defense. Drive technical excellence across optical, RF, and algorithm domains i...

1 week ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$80K - $100K *

Join a dynamic team to advance environmental projects across the Southeast. Utilize your expertise in field investigations, project management, and compliance to lead diverse initiatives, while foster...

6 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$180K - $210K *

Drive your career by leading innovative platform engineering initiatives that support enterprise AI projects. Collaborate with cross-functional teams to enhance developer productivity and deploy secur...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Shape the future of electronics innovation by leading strategic account management and GTM strategies for groundbreaking software solutions in scientific workflows across global markets...

4 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$150K - $180K *

Lead the charge in fostering innovative partnerships across global accounts, leveraging advanced atomic-scale modeling to drive breakthroughs in electronics and semiconductors, while aligning strategi...

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Join a team that drives innovation in electronics by coordinating strategic enterprise relationships, designing Go-to-Market strategies, and enhancing product adoption for impactful software solutions...

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Empower progress by driving strategic partnerships in the electronics sector, translating complex scientific innovations into business value while leading account management efforts across global mark...

4 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$150K - $245K *

Join a team that's committed to advancing pharmacometric strategies through sophisticated analyses that enhance program development and regulatory submissions while mentoring junior staff and ensuring...

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.