Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Staff Engineer, Chemical Search
$180K - $200K *
Develop a cutting-edge chemistry search engine, integrating advanced predictive models to support medicinal chemists and AI-driven design teams in navigating vast chemical spaces efficiently and accur...
1 week ago
$112K - $190K *
Lead transformative construction projects by managing all phases from pre-construction to close-out. Collaborate with stakeholders and ensure efficient delivery while maintaining budget and quality ac...
2 weeks ago
$120K - $150K *
Lead the charge in driving innovative disease modeling efforts by managing a team of data scientists, leveraging statistical and machine learning techniques to produce impactful healthcare solutions a...
Reposted 1 week ago
Senior Project Director (Mining)
$134K - $168K *
Lead complex environmental programs in mining, ensuring compliance, governance, and effective project delivery through multi-disciplinary collaboration and robust planning...
2 weeks ago
Senior Project Director (Mining)
$134K - $168K *
Transform complex environmental programs through effective governance and project delivery. Lead multi-disciplinary teams, ensure regulatory compliance, and drive efficiency in high-stakes mining proj...
2 weeks ago
Senior Project Director (Mining)
$134K - $168K *
Pioneer your career by leading complex mining projects with a focus on regulatory compliance, ensuring quality and excellence in environmental program delivery while managing multi-disciplinary teams...
2 weeks ago
Senior Project Director (Mining)
$134K - $168K *
Lead the charge in delivering complex mining projects while ensuring regulatory compliance, fostering team collaboration, and maintaining project governance. Your leadership will drive safety and cont...
2 weeks ago
Senior Project Director (Mining)
$134K - $168K *
Drive compliance and assurance in complex mining environmental programs by leading multi-disciplinary teams and ensuring project governance. Leverage expertise to deliver safe, high-quality outcomes w...
2 weeks ago
Senior Project Director (Mining)
$134K - $168K *
Innovate strategic project delivery in complex mining and environmental programs. Lead a multi-disciplinary team to ensure compliance and governance, delivering high-risk projects with a focus on qual...
2 weeks ago
Senior Project Director (Mining)
$134K - $168K *
Transform the mining sector by delivering complex environmental programs with a focus on regulatory compliance and project governance. Lead multidisciplinary teams to ensure quality execution and driv...
2 weeks ago
Senior Project Director (Mining)
$134K - $168K *
Unlock potential by leading complex environmental projects within mining, ensuring compliance and governance while managing multi-disciplinary teams. Drive safety culture and continuous improvement th...
2 weeks ago
Senior Project Director (Mining)
$134K - $168K *
Join a team that's committed to delivering compliant and high-impact environmental programs. Lead multi-disciplinary teams, ensuring project governance, quality, and regulatory standards are met while...
2 weeks ago
$268K - $402K *
Drive the DMPK-BA strategy for our Biotherapeutics portfolio, guiding teams from research to development. Lead innovative approaches in a matrixed environment while ensuring scientific excellence and...
4 weeks ago
Senior Project Director (Mining)
$134K - $168K *
Shape the future of environmental compliance by leading complex mining projects, ensuring effective governance and delivery within regulated environments while enhancing safety and efficiency across m...
2 weeks ago
Senior Project Director (Mining)
$134K - $168K *
Join a team dedicated to delivering complex mining projects with compliance and assurance. You'll lead multi-disciplinary teams, ensuring adherence to technical standards, regulatory requirements, and...
2 weeks ago
Senior Project Director (Mining)
$134K - $168K *
Optimize delivery leadership and governance of environmental programs in the mining sector, ensuring compliance, quality, and stakeholder communication while managing multi-disciplinary teams through...
2 weeks ago
Senior Project Director (Mining)
$134K - $168K *
Join a dynamic team focusing on environmental programs in mining, overseeing complex projects while ensuring compliance, quality, and governance. Leverage your leadership skills to enhance project exe...
2 weeks ago
Sr. Research Associate, Drug Product Development
$82K - $103K *
Transform drug product development by executing lab experiments and data analysis, collaborating with cross-functional teams, and ensuring compliance for early-phase clinical trials, while contributin...
1 week ago
Research Engineer, Materials Science
$141K - $202K *
Transform scientific discovery by developing software tools for high-performance simulations and AI applications in interdisciplinary materials science research. Collaborate with experts to push bound...
Reposted 1 week ago
Senior Principal Agentic Technologist
$220K - $300K *
Transform healthcare technology as a technical leader, directing AI agent architecture, enhancing operational excellence, and fostering cross-team collaboration to drive innovation and efficiency in h...
Yesterday
Senior Chemist – Specialty Adhesives R&D
$80K - $110K *
Transform complex technical challenges into innovative solutions by providing leadership in specialty adhesive technologies, bridging formulation with application and performance to enhance product qu...
2 weeks ago
Senior Principal Agentic Technologist
$220K - $300K *
Join a team that's shaping cutting-edge AI agent workflows in healthcare. Lead architecture, security, and DevOps practices while mentoring engineers and establishing best practices, ensuring operatio...
Yesterday
Senior Clinical Development Scientist
$148K - $237K *
Transform your career with a pivotal role driving clinical evidence for innovative ultrasound solutions, collaborating with diverse stakeholders to enhance regulatory strategies and improve patient ou...
5 days ago
Sr. Director-Purification and Viral Safety
$156K - $228K *
Shape the future of bioproduct development by leading purification and viral safety CMC efforts. Drive strategic direction, innovation, and platform improvements while collaborating cross-functionally...
2 weeks ago
Senior Scientist I / II - Biologics Analytical R&D
$100K - $130K *
Join a team that's pioneering analytical techniques for biologics, driving the development of innovative therapeutics, and collaborating across global functions to enhance product development and exec...
3 days ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.