Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Senior Principal Process Control & Automation Engineer
$66K - $171K *
Join us to lead the implementation and enhancement of automation solutions for a state-of-the-art manufacturing facility. Collaborate with cross-functional teams to ensure compliance and optimize proc...
3 weeks ago
Senior Principal Process Control & Automation Engineer
$66K - $171K *
Join our team as a Process Control and Automation Engineer, where you will lead the development and implementation of cutting-edge automation solutions for a new manufacturing facility, ensuring GMP c...
3 weeks ago
Food Scientist II, Consumer and Product Insights and Foresights
$80K - $115K *
Innovate insights through data analysis, consumer research, and sensory science. As an individual contributor, grow your expertise while impacting product understanding and consumer experiences with e...
3 weeks ago
Associate Principal Scientist - Environmental Monitoring/Microbiology
$100K - $130K *
Drive contamination control initiatives as a leader in Quality Control, managing microbial risks and fostering a proactive culture in manufacturing. Engage cross-functionally to ensure compliance and...
2 weeks ago
Senior Applied Scientist, Full-funnel Agentic Intelligence and Models
$192K - $260K *
Drive innovative machine learning solutions to enhance shopping experiences across diverse platforms. Collaborate with product and technical teams to transform advanced research into impactful campaig...
Reposted 3 days ago
Senior Clinical Research Scientist
$144K - $216K *
Make your mark at the forefront of clinical research by contributing to global development strategies and leading clinical trials collaboratively. Engage with cross-functional teams to deliver high-qu...
2 weeks ago
Senior Hyperspectral Image Scientist
$92K - $166K *
Drive advanced hyperspectral image analysis and exploitation to support government missions, blending expertise in spectral processing, algorithm development, and remote sensing with cross-disciplinar...
2 weeks ago
Senior Manager, Material Characterization Scientist
$137K - $160K *
Join a team that's transforming analytical capabilities by leading material characterization efforts to drive R&D innovation. Collaborate across disciplines to develop methods and deliver insights tha...
Reposted 5 days ago
$60K - $121K *
Champion innovation in our dynamic lab environment. As a Senior Production Chemist, you'll collaborate with cross-functional teams to execute GMP processes in mammalian cell culture, ensuring high-qua...
3 weeks ago
$170K - $220K *
Pioneer innovative lab solutions by leading a team to enhance operational efficiency and data integrity across multiple lab locations while driving strategic AI-first initiatives and team collaboratio...
2 days ago
$90K - $120K *
Deliver excellence in facilities engineering by overseeing maintenance programs, troubleshooting complex systems, and ensuring compliance with GMP standards across diverse environments, while mentorin...
2 days ago
Manager/ Staff Systems Engineer
$150K - $175K *
Engage with cross-functional teams to advance system-level performance and quality in product development for life sciences, bridging engineering and design to deliver effective solutions throughout p...
3 weeks ago
Member of the Technical Staff, Cheminformatics
$120K - $150K *
Accelerate the synthesis of molecules by developing advanced computational models and methods. Build scalable tools and analyze molecular data while partnering with teams to optimize candidate selecti...
2 days ago
Member of the Technical Staff, Cheminformatics
$120K - $150K *
Engineer innovative models and tools to transform molecular generation into practical chemistry, collaborating across teams to advance drug discovery and enhance cheminformatics capabilities in a dyna...
2 days ago
Scientific Applications Developer
$90K - $120K *
Collaborate with interdisciplinary teams to design, validate, and optimize scientific applications within NOAA's operational frameworks, leveraging advanced programming skills to enhance meteorologica...
6 days ago
Applied Scientist, Amazon Business Ads
$172K - $223K *
Drive innovation by developing advanced advertising solutions, leading research, and delivering clear results. Collaborate across teams to execute B2B ad projects, using statistical techniques and fos...
Reposted 5 days ago
$72K - $110K *
Grow innovative solutions in computational biology to tackle viral outbreaks. Lead a dynamic team in analyzing large datasets and developing predictive models for infectious diseases while collaborati...
Reposted 6 days ago
$72K - $110K *
Unlock potential by leading computational biology projects to analyze influenza dynamics, develop predictive models, and collaborate with multidisciplinary teams to advance scientific research and pub...
Reposted 6 days ago
Discovery Oncology Scientific Lead
$138K - $224K *
Deliver innovative strategies for target discovery in oncology by leveraging advanced genetic medicine technologies. Collaborate with a multi-disciplinary team to advance cancer drug therapy through e...
2 weeks ago
$103K - $236K *
Play a key role in enhancing next-generation sequencing solutions by integrating subcomponents and conducting hands-on experiments. Collaborate with a dynamic team to develop innovative technologies i...
2 weeks ago
$90K - $120K *
Inspire success by leading large-scale, multi-year projects with rigorous safety and regulatory oversight, ensuring on-time delivery while effectively managing resources, risks, and stakeholder commun...
3 weeks ago
Laboratory Manager and Technologist
$75K - $95K *
Lead a dynamic, technical team in a laboratory setting focused on plastics testing. Oversee operations, ensure safety and data integrity, and drive innovation while performing hands-on experiments to...
Reposted 2 days ago
Scientist II, Assay Operations, Screening Platform Technologies
$132K - $166K *
Innovate in cellular screening as part of a dynamic team supporting oncology drug discovery, optimizing high-throughput assays, and enhancing automation workflows. Collaborate across disciplines to dr...
2 days ago
$66K - $171K *
Unlock potential as you lead critical validation initiatives to ensure compliant manufacturing. Provide technical expertise in cleaning, sterilization, and validation processes while mentoring a dynam...
1 week ago
Principal Environmental Professional or Biologist
$150K - $180K *
Shape the future of environmental compliance and permitting projects, leading teams to ensure client satisfaction and project success while fostering professional development and managing multidiscipl...
3 weeks ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.