Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$66K - $171K *

Join us to lead the implementation and enhancement of automation solutions for a state-of-the-art manufacturing facility. Collaborate with cross-functional teams to ensure compliance and optimize proc...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$66K - $171K *

Join our team as a Process Control and Automation Engineer, where you will lead the development and implementation of cutting-edge automation solutions for a new manufacturing facility, ensuring GMP c...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $115K *

Innovate insights through data analysis, consumer research, and sensory science. As an individual contributor, grow your expertise while impacting product understanding and consumer experiences with e...

3 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $130K *

Drive contamination control initiatives as a leader in Quality Control, managing microbial risks and fostering a proactive culture in manufacturing. Engage cross-functionally to ensure compliance and...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$192K - $260K *

Drive innovative machine learning solutions to enhance shopping experiences across diverse platforms. Collaborate with product and technical teams to transform advanced research into impactful campaig...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$144K - $216K *

Make your mark at the forefront of clinical research by contributing to global development strategies and leading clinical trials collaboratively. Engage with cross-functional teams to deliver high-qu...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$92K - $166K *

Drive advanced hyperspectral image analysis and exploitation to support government missions, blending expertise in spectral processing, algorithm development, and remote sensing with cross-disciplinar...

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$137K - $160K *

Join a team that's transforming analytical capabilities by leading material characterization efforts to drive R&D innovation. Collaborate across disciplines to develop methods and deliver insights tha...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$60K - $121K *

Champion innovation in our dynamic lab environment. As a Senior Production Chemist, you'll collaborate with cross-functional teams to execute GMP processes in mammalian cell culture, ensuring high-qua...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$170K - $220K *

Pioneer innovative lab solutions by leading a team to enhance operational efficiency and data integrity across multiple lab locations while driving strategic AI-first initiatives and team collaboratio...

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $120K *

Deliver excellence in facilities engineering by overseeing maintenance programs, troubleshooting complex systems, and ensuring compliance with GMP standards across diverse environments, while mentorin...

2 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $175K *

Engage with cross-functional teams to advance system-level performance and quality in product development for life sciences, bridging engineering and design to deliver effective solutions throughout p...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Accelerate the synthesis of molecules by developing advanced computational models and methods. Build scalable tools and analyze molecular data while partnering with teams to optimize candidate selecti...

US-AnywhereRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Engineer innovative models and tools to transform molecular generation into practical chemistry, collaborating across teams to advance drug discovery and enhance cheminformatics capabilities in a dyna...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Collaborate with interdisciplinary teams to design, validate, and optimize scientific applications within NOAA's operational frameworks, leveraging advanced programming skills to enhance meteorologica...

US-AnywhereRemote

6 days ago

  •   Less than 5 years exp.  •   Technical Services

$172K - $223K *

Drive innovation by developing advanced advertising solutions, leading research, and delivering clear results. Collaborate across teams to execute B2B ad projects, using statistical techniques and fos...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$72K - $110K *

Grow innovative solutions in computational biology to tackle viral outbreaks. Lead a dynamic team in analyzing large datasets and developing predictive models for infectious diseases while collaborati...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $110K *

Unlock potential by leading computational biology projects to analyze influenza dynamics, develop predictive models, and collaborate with multidisciplinary teams to advance scientific research and pub...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$138K - $224K *

Deliver innovative strategies for target discovery in oncology by leveraging advanced genetic medicine technologies. Collaborate with a multi-disciplinary team to advance cancer drug therapy through e...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$103K - $236K *

Play a key role in enhancing next-generation sequencing solutions by integrating subcomponents and conducting hands-on experiments. Collaborate with a dynamic team to develop innovative technologies i...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Inspire success by leading large-scale, multi-year projects with rigorous safety and regulatory oversight, ensuring on-time delivery while effectively managing resources, risks, and stakeholder commun...

Chalk River, ONIn-Person

3 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$75K - $95K *

Lead a dynamic, technical team in a laboratory setting focused on plastics testing. Oversee operations, ensure safety and data integrity, and drive innovation while performing hands-on experiments to...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$132K - $166K *

Innovate in cellular screening as part of a dynamic team supporting oncology drug discovery, optimizing high-throughput assays, and enhancing automation workflows. Collaborate across disciplines to dr...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$66K - $171K *

Unlock potential as you lead critical validation initiatives to ensure compliant manufacturing. Provide technical expertise in cleaning, sterilization, and validation processes while mentoring a dynam...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Shape the future of environmental compliance and permitting projects, leading teams to ensure client satisfaction and project success while fostering professional development and managing multidiscipl...

US-AnywhereRemote

3 weeks ago

  •   11 - 15 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.