Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
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$172K - $236K *

Join a team that drives semiconductor innovation by providing technical leadership, tackling complex process challenges, and enhancing customer engagement to deliver next-generation solutions and elev...

3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$172K - $236K *

Pioneer innovative semiconductor solutions by leveraging deep process expertise. Lead customer engagements, drive technology adoption, and foster strategic partnerships with top manufacturers to overc...

3 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$172K - $236K *

Collaborate with top semiconductor manufacturers to address complex process challenges, drive technology adoption, and influence product development. Your expertise will shape future innovations while...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Oversee and optimize preclinical to clinical analytical development, managing QC methods and ensuring compliance at contract manufacturers. Collaborate on specifications and support regulatory submiss...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$136K - $170K *

Deliver technical leadership for AOC and AAV drug substance programs, enhancing process development, scale-up, and manufacturing oversight while ensuring compliance and quality throughout the producti...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$75K - $108K *

Contribute to the development of oral solid dosage formulations, supporting design, optimization, and technology transfer. Collaborate with CMC teams and apply hands-on skills to advance drug candidat...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$126K - $181K *

Lead scientific initiatives in CAR-T therapy development while conducting in vitro and in vivo experiments. Collaborate with multidisciplinary teams to drive strategic planning, analyze data, and cont...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$148K - $276K *

Lead the charge in defining innovative product strategies within drug discovery, collaborating across teams to drive impactful solutions and enhance the data ecosystem, ultimately accelerating the del...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$97K - $138K *

Join a team that's dedicated to advancing metallurgical testing and analysis. Provide expert guidance, lead complex studies, and improve processes at a premier facility while ensuring compliance and s...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$145K - $165K *

Transform the delivery of HSIN Program services by leading a contract team, overseeing all project aspects, and enhancing information-sharing across the FSLTTIP community through strategic stakeholder...

2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Transform the future of analytical service offerings by defining strategy, leading lifecycle management, and leveraging AI for enhanced customer outcomes while collaborating with cross-functional team...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Manage complex R&D programs, bridging teams to deliver innovative solutions. Ensure project success through effective budget and schedule oversight while collaborating with stakeholders to achieve str...

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$131K - $165K *

Innovate clinical solutions by leading global study design and scientific strategy. Drive regulatory submissions and evidence generation, collaborating across teams to enhance medical device technolog...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$145K - $240K *

Join a team that's redefining health outcomes through cutting-edge research. Leverage your expertise in human physiology and regenerative medicine to support innovative programs in transplantation and...

US-AnywhereRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $130K *

Advance your career by developing enzymatic assays that drive scientific discoveries and support partner programs. Collaborate closely within a dynamic team to transform initial concepts into robust...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Partner with us to design and implement advanced analytical models that solve complex business challenges, while leading a talented data science team to drive insights and foster sustainable solutions...

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$100K - $150K *

Shape a culture of safety by leading EHS initiatives in a dynamic biotech environment. Drive compliance, manage risks, and innovate EHS practices to support process development and GMP manufacturing o...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Join our team to lead analytical testing and method development in a cGMP lab. Drive project success through expert judgment, data integrity, and proactive mentoring in a dynamic, client-focused envir...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$173K - $237K *

Lead the design and execution of advanced drug product formulation and process development activities, ensuring alignment with corporate objectives and regulatory standards across the product lifecycl...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$98K - $154K *

Partner with us to drive biologics discovery by characterizing protein therapeutics through innovative biosensor and biochemical technologies. You'll optimize assays and collaborate with project teams...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$109K - $179K *

Champion cutting-edge generative AI applications for biomolecule design and optimization, collaborating with cross-functional teams to accelerate therapeutic development for multiple diseases...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$142K - $224K *

Join a dynamic team to innovate and optimize downstream purification processes for biological products, collaborating across functions to drive development and improve process technology from early-st...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$207K - $258K *

Unlock potential by providing expert leadership in process chemistry for small molecule development, collaborating cross-functionally to innovate manufacturing strategies and ensure seamless progressi...

US-AnywhereRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$200K - $280K *

Join us to lead cutting-edge optoelectronic development programs. Oversee multi-disciplinary teams, manage risk, and drive project execution from inception to manufacturing for innovative products in...

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$80K - $95K *

Develop and optimize cutting-edge biosensor assays through innovative experimental design, supporting laboratory operations and product development to ensure high-quality diagnostics and research appl...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.