Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Principal Research Scientist, Amazon Ads, Ads Science Analysis & Tech (ASAT)
$208K - $281K *
Transform advertising analytics by leveraging data analysis to enhance optimization, targeting, and strategic decisions within complex ecosystems. Collaborate with engineering and product teams for im...
1 week ago
Sr. Project Manager, Quality Assurance (QA)
$101K - $135K *
Lead quality assurance initiatives to enhance compliance, foster continuous improvement, and ensure adherence to cGMP standards in biopharmaceutical manufacturing while mentoring and guiding the QA te...
3 days ago
Head of Product Science and Lab Operations (MSAT) (Director)
$151K - $281K *
Lead a dynamic team in shaping advanced cell therapy platforms through innovation, data-driven strategies, and cross-functional collaboration. Drive process validation and technology transfer to enabl...
2 weeks ago
$100K - $300K *
Champion original research in automated reasoning and AI-driven security, applying innovative techniques and collaborating with engineering teams to impact real-world infrastructures and enhance machi...
3 weeks ago
$100K - $300K *
Pioneer advanced research in automated reasoning and AI-driven code analysis to create innovative solutions. Collaborate cross-functionally, publish findings, and impact safety and efficiency in globa...
3 weeks ago
$80K - $100K *
Join a team that's dedicated to successfully managing key projects that drive innovation and business growth. You will coordinate cross-functional efforts, ensuring projects stay on track and meet str...
2 weeks ago
Senior Director, Product Management
$180K - $220K *
Unlock potential by owning the strategy and execution of a critical product area, driving innovation and alignment across teams, mentoring peers, and engaging with customers at all levels while influe...
1 week ago
Senior Director Program Management
$233K - $321K *
Advance your career by leading a global program management team, ensuring innovative product delivery from concept to market, while driving cross-functional collaboration and embracing modern tools to...
1 week ago
Principal CNO Software Engineer
$200K - $280K *
Lead the charge in architecting and developing cutting-edge CNO software solutions that enhance critical government operations. Collaborate with multi-disciplinary teams to deliver impactful technolog...
3 weeks ago
Senior/Staff Statistician, Assay Development
$150K - $215K *
Lead analytical validation studies for cancer detection assays by applying advanced statistical methods. Collaborate across teams to ensure rigorous standards and mentor junior staff while supporting...
3 weeks ago
Senior Principal Scientist, Clinical Research, Immunology - Ophthalmology
$282K - $444K *
Contribute to advancing Immunology by managing clinical research for investigational compounds, overseeing all phases of clinical trials and ensuring robust evaluation of safety and efficacy to drive...
Reposted 1 week ago
Project Manager | Recovery Sciences
$90K - $120K *
Accelerate progress at delivering innovative medical devices through effective project management and cross-team collaboration, ensuring timely product launches and strategic process improvements in a...
3 weeks ago
$90K - $120K *
Unlock success by leading integration strategies and enhancing collaboration among engineering, quality, and regulatory teams to drive complex medical device projects forward in a dynamic, fast-paced...
1 week ago
$100K - $105K *
Grow your career with a dynamic role that blends clinical research coordination and site management, ensuring compliance, staff development, and patient engagement to drive operational excellence and...
5 days ago
Director, Engineering (Filtration)
$165K - $250K *
Join a team that's driving excellence in manufacturing engineering. Lead process optimization and innovation to enhance production scalability, product quality, and operational efficiency while mentor...
Reposted 2 weeks ago
Senior Principal Process Control & Automation Engineer
$66K - $171K *
Join us to lead the implementation and enhancement of automation solutions for a state-of-the-art manufacturing facility. Collaborate with cross-functional teams to ensure compliance and optimize proc...
3 weeks ago
Senior Principal Process Control & Automation Engineer
$66K - $171K *
Join our team as a Process Control and Automation Engineer, where you will lead the development and implementation of cutting-edge automation solutions for a new manufacturing facility, ensuring GMP c...
3 weeks ago
Food Scientist II, Consumer and Product Insights and Foresights
$80K - $115K *
Innovate insights through data analysis, consumer research, and sensory science. As an individual contributor, grow your expertise while impacting product understanding and consumer experiences with e...
3 weeks ago
Associate Principal Scientist - Environmental Monitoring/Microbiology
$100K - $130K *
Drive contamination control initiatives as a leader in Quality Control, managing microbial risks and fostering a proactive culture in manufacturing. Engage cross-functionally to ensure compliance and...
2 weeks ago
Senior Applied Scientist, Full-funnel Agentic Intelligence and Models
$192K - $260K *
Drive innovative machine learning solutions to enhance shopping experiences across diverse platforms. Collaborate with product and technical teams to transform advanced research into impactful campaig...
Reposted 4 days ago
Senior Clinical Research Scientist
$144K - $216K *
Make your mark at the forefront of clinical research by contributing to global development strategies and leading clinical trials collaboratively. Engage with cross-functional teams to deliver high-qu...
2 weeks ago
Senior Hyperspectral Image Scientist
$92K - $166K *
Drive advanced hyperspectral image analysis and exploitation to support government missions, blending expertise in spectral processing, algorithm development, and remote sensing with cross-disciplinar...
2 weeks ago
Senior Manager, Material Characterization Scientist
$137K - $160K *
Join a team that's transforming analytical capabilities by leading material characterization efforts to drive R&D innovation. Collaborate across disciplines to develop methods and deliver insights tha...
Reposted 6 days ago
$60K - $121K *
Champion innovation in our dynamic lab environment. As a Senior Production Chemist, you'll collaborate with cross-functional teams to execute GMP processes in mammalian cell culture, ensuring high-qua...
3 weeks ago
$170K - $220K *
Pioneer innovative lab solutions by leading a team to enhance operational efficiency and data integrity across multiple lab locations while driving strategic AI-first initiatives and team collaboratio...
4 days ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.