Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.
California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.
Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.
Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.
Senior Safety Physician - CNS (remote)
$222K - $356K *
Unlock your potential as a Senior Safety Physician, leading safety oversight for late-stage CNS clinical development. Collaborate with cross-functional teams to drive risk management and regulatory su...
Reposted 2 weeks ago
Clinical Specialist | Urology - Prosthetic Urology | Los Angeles, CA
$85K *
Empower healthcare providers by delivering expert clinical support in prosthetic urology. Collaborate with teams to enhance patient outcomes through education, hands-on guidance, and compassionate car...
5 days ago
$110K - $130K *
Empower patients by providing comprehensive psychiatric care and treatment. Collaborate with a dedicated healthcare team to develop effective management plans and promote evidence-based practices in a...
2 weeks ago
$105K - $113K *
Build a dynamic HR function to support employee lifecycle processes, ensuring operational excellence and compliance while enhancing the employee experience across all levels of the organization...
Reposted 1 week ago
Director of Patient Care Services (DPCS)
$110K - $130K *
Manage and oversee health delivery systems, ensuring high-quality patient care and clinician performance while promoting improvement across services. Collaborate with leadership to sustain operational...
4 weeks ago
$80K - $110K *
Deliver compassionate teletherapy to clients, ensuring effective treatment and support. Join a mission-driven team enhancing mental wellness through personalized care, collaboration, and innovative so...
Reposted 3 weeks ago
Associate Principal, Architect - Federal Healthcare
$120K - $180K *
Drive growth in Federal Healthcare by leading multidisciplinary teams in the planning, design, and delivery of innovative projects. Collaborate with clients and stakeholders to ensure project excellen...
2 weeks ago
Associate Principal, Architect - Federal Healthcare
$120K - $180K *
Lead the charge in delivering innovative Federal healthcare projects while driving business growth. Collaborate with multidisciplinary teams to enhance client relationships and ensure project excellen...
2 weeks ago
$180K - $220K *
Unlock your potential by driving enterprise growth in healthcare. Join a dynamic team focused on building relationships with health systems and provider organizations, leveraging a robust support engi...
4 days ago
$250K - $300K *
Join a team that's committed to providing exceptional patient care in a dynamic environment. Collaborate with diverse medical professionals while enjoying a strong work-life balance within a growing a...
Reposted 3 weeks ago
$95K - $100K *
Manage resident care and medication coordination, ensuring independence and health through effective communication with healthcare professionals and oversight of nursing staff in a supportive environm...
1 week ago
Clinical Nurse II - Acute Rehab - Nights - FT
$85K - $100K *
Collaborate with interdisciplinary teams to deliver comprehensive patient care, evaluate outcomes, and mentor new nurses. This role requires adaptability in a dynamic environment, ensuring effective r...
4 days ago
$250K - $300K *
Lead a dynamic neurology practice focused on patient-centered care, specializing in EEG, EMG, and pain management. Collaborate with a supportive team to diagnose and manage diverse neurological condit...
1 week ago
$100K *
Transform lives by delivering personalized fitness training and support. Engage clients with tailored programs, expert guidance, and exceptional service while achieving personal and team revenue goals...
4 weeks ago
Clinical Testing Psychologist (PsyD & PhD)
$108K - $145K *
Optimize patient care by delivering high-quality psychological services. Engage with diverse populations through testing and therapy, while contributing to a collaborative clinical team focused on exc...
3 weeks ago
Advanced Practice Provider (Nurse Practitioner or Physician Assistant)
$100K - $120K *
Join a team that's dedicated to delivering high-quality pediatric care. As an Advanced Practice Provider, you'll assess, diagnose, and implement treatment plans while collaborating with physicians to...
1 week ago
Medical Director, Clinical Development-Rheumatology
$210K - $250K *
Join a team that's shaping the future of rheumatology clinical development, leading trials and ensuring optimal medical oversight for high-quality data interpretation and regulatory compliance to driv...
Reposted 1 week ago
$85K - $120K *
Transform healthcare sales by building strong physician relationships and driving referrals in oncology, hematology, gastroenterology, and rheumatology. Leverage your expertise to achieve sales goals...
2 weeks ago
Principal Scientist, Translational Biology
$202K - $236K *
Unlock potential by leading biomarker discovery at the intersection of genetics, multi-omics, and AI/ML. Collaborate with biologists and clinicians to translate insights into precision medicine for ca...
Reposted 1 week ago
$110K - $130K *
Redefine the delivery of orthotic and prosthetic services by providing clinical and operational leadership, ensuring high-quality patient care, and driving continuous improvement in clinical workflows...
2 weeks ago
$145K *
Drive impactful solutions by leveraging data-driven methodologies to solve complex client challenges. Collaborate with teams to develop financial models, market strategies, and insightful analyses tha...
1 week ago
$160K - $200K *
Unlock your potential as a Pediatric Dentist, providing specialized care to children while collaborating with a dedicated team. Enjoy a supportive environment focused on quality treatment and complian...
3 weeks ago
Embryologist / Senior Embryologist
$170K *
Tackle the future of reproductive technology by executing precise embryology procedures, supporting patient care, and driving research initiatives in a collaborative environment dedicated to innovatio...
3 weeks ago
Field Clinical Specialist, Los Angeles East
$95K - $115K *
Grow your career with a role that combines clinical expertise and training to support medical professionals using specialty devices, ensuring patient safety and effective product utilization in divers...
1 month ago
Clinical Psychologist (PsyD, PhD)
$136K - $182K *
Engage with patients as a vital member of our clinical team, providing exceptional psychological care. Enjoy flexible schedules, modern facilities, and a supportive environment while making a meaningf...
3 weeks ago
What types of $100,000+ jobs can I find in California?
California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.
Where in California can I search for jobs?
You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.
Can I find remote or hybrid California jobs?
Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.
How can I improve my California job search?
Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.