Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,442

Sort By: Relevance

$95K - $115K *

Join a dynamic team to enhance hybrid infrastructure, ensuring system reliability and security across diverse environments. Collaborate with cross-functional teams to implement solutions and optimize...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$115K - $130K *

Empower client success by managing accounting projects and implementations. Drive efficiency through process improvements and AI tools while ensuring accurate, timely deliverables. Collaborate with te...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$91K - $169K *

Join a team that's dedicated to designing and developing innovative software solutions. Collaborate on integration and testing, ensuring high standards throughout the software development life cycle w...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$210K - $331K *

Drive scientific exchange and research initiatives as a key liaison between the scientific community and the organization, enhancing understanding of therapeutic areas and supporting clinical developm...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$107K - $135K *

Shape your career by providing engineering solutions for underground mining equipment, collaborating with teams to enhance product functionality, and ensuring compliance with safety regulations. Your...

Reposted today

  •   Less than 5 years exp.  •   Energy & Utilities

$80K - $95K *

Engage with customers to drive sales growth by mastering product knowledge, building relationships, and executing project pursuits. Collaborate with teams to maximize opportunities and deliver excepti...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$69K - $104K *

Unlock potential by leading financial reporting and investment oversight for a key retirement plan. Collaborate with teams to ensure accurate accounting and compliance while mentoring junior staff in...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$119K - $167K *

Lead the charge in evolving our cloud infrastructure and CI/CD systems. As a Senior DevOps Engineer, you'll enhance security, reliability, and operational efficiency while mentoring a team and ensurin...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$141K - $166K *

Advance your career by managing a portfolio of high-capacity donors, developing tailored engagement strategies, and collaborating with leadership to secure major gifts that support our mission in the...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$110K - $150K *

Transform production services with a robust Site Reliability Engineering approach. Collaborate with teams to enhance availability, resiliency, and operational automation while driving continuous impro...

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$110K - $150K *

Join us to enhance the reliability and performance of our 24/7 SaaS platform. Collaborate with cross-functional teams to implement engineering practices that drive operational excellence and continuou...

Philadelphia, PARemote

Today

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Empower your career by driving innovative application development in engineered materials. Collaborate across teams to enhance product offerings in building and construction and electrical markets, en...

Today

  •   5 - 7 years exp.  •   Business Services

$160K - $200K *

Lead the development and execution of data management strategies, ensuring effective governance and utilization of data assets across the organization. Collaborate with stakeholders to enhance data pr...

Today

  •   11 - 15 years exp.  •   Hospitals & Medical Centers

$170K - $200K *

Lead the development and execution of data management strategies, ensuring effective governance and utilization of data assets across the organization. Collaborate with stakeholders to enhance data pr...

Today

  •   11 - 15 years exp.  •   Hospitals & Medical Centers

$77K - $202K *

Shape the future of healthcare by driving payer platform modernization. As a Senior Associate, you'll analyze complex issues, manage workstreams, and mentor junior team members while enhancing client...

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$77K - $202K *

Analyze complex healthcare payer platform issues, manage workstreams, and mentor junior team members to enhance operational performance and member experiences using Epic software and industry best pra...

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

Join a team that's driving regional growth by leading sales strategies, developing partnerships, and expanding access to advanced imaging services. This high-impact role influences patient volume and...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive strategic growth initiatives by independently managing mid-market customer relationships and executing effective sales strategies to enhance retention and expansion across your portfolio of acco...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$134K - $160K *

Lead the charge in paid social strategy and performance for eCommerce brands. Drive measurable growth, mentor teams, and elevate operational standards while navigating complex client challenges with c...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Transform project delivery by leading cross-functional teams to ensure timely execution of Public Safety product implementations, enhancing client satisfaction and operational efficiency through exper...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$113K - $188K *

Pioneer a transformative Agile project management role overseeing large-scale software development. Lead coordination and execution across multiple teams and workstreams while ensuring alignment with...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Business Services

$145K - $190K *

Join a team that's dedicated to supporting educational institutions by providing expert legal counsel on governance, compliance, and operational matters. Collaborate with public entities to navigate c...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$200K - $260K *

Lead strategic partnerships to elevate and scale multi-year AI and LLM relationships. Collaborate cross-functionally to deepen alliances, drive integration optimizations, and advance collaborative opp...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Shape the future of client management by leading service teams on large accounts, enhancing carrier relationships, and developing strategic placement and renewal plans to drive success and improve pro...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$124K - $165K *

Innovate the Federal and Defense marketing strategy by executing integrated, multi-channel programs that drive pipeline growth. Collaborate closely with sales leadership to engage diverse federal audi...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.