Find Your Next High-Paying Job in Pennsylvania

Are you a professional seeking $100K+ jobs in Pennsylvania? You've come to the right place. Ladders is your hub for high-paying Pennsylvania jobs across a broad range of industries, including Tech, Finance, Healthcare, and more.

Unlock Opportunities in Pennsylvania

Pennsylvania, known for its rich history and diverse job market, offers a plethora if opportunities for ambitious professionals seeking high-paying jobs.

How Ladders Can Help

Whether you're looking for jobs in Philadelphia, Pittsburgh, or smaller cities within Pennsylvania, Ladders has got you covered. Our selection of $100K+ jobs in Pennsylvania is carefully curated and regularly updated. Start your job searc on Ladders today!

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $120,902

Sort By: Relevance

$70K - $95K *

Join a team that's focused on enhancing manufacturing efficiency and safety. You will provide technical support, develop innovative processes, and lead improvement initiatives to meet operational goal...

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$116K - $160K *

Join a team that's leading the charge in architecting complex systems and integrating AI-driven development tools. This role empowers you to shape scalable architectures while enhancing engineering pr...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$80K - $108K *

Lead the charge in developing strategies to grow referral business and build relationships with partners. Collaborate across departments to analyze sales data and ensure a seamless referral process, d...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Business Services

$80K - $125K *

Lead the charge in customer experience enhancement by leveraging data and insights to drive scalable support solutions. Collaborate with cross-functional teams to design strategies that ensure seamles...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$184K - $245K *

Drive legal excellence by managing M&A diligence, enhancing contract processes, and strengthening legal operations. Collaborate cross-functionally to optimize deal execution and support acquisition-re...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$144K - $200K *

Transform the future of education by leading strategic initiatives in AP Course development and product readiness, driving operational excellence and cross-functional collaboration to ensure high-qual...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$220K - $250K *

Lead and enhance the information security framework ensuring compliance, safeguarding data, and managing cyber risks for a global enterprise while aligning security initiatives with business objective...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Champion the statistical strategies for clinical development and regulatory submissions, leading cross-functional collaborations. Drive innovative design and deliver accurate analyses while ensuring c...

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $180K *

Drive value from digital and technology investments by ensuring measurable benefits, collaborating with I&T and finance leaders to track performance, identify risks, and optimize ROI across the enterp...

Yesterday

  •   8 - 10 years exp.  •   Business Services

$250K - $280K *

Accelerate progress at the forefront of clinical trial management by establishing and optimizing frameworks that ensure exceptional quality across Portfolio Development, collaborating with diverse tea...

Yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$97K - $172K *

Join a dynamic team as you lead insurance product rollouts and pricing changes. Drive efficiency and quality while collaborating with cross-functional stakeholders to bring innovative products to mark...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $128K *

Unlock potential by leveraging advanced analytics and financial insights to enhance decision-making and drive profitable growth across commercial teams. Engage with stakeholders to ensure data integri...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $220K *

Lead the charge in driving customer success strategies while mentoring a multidisciplinary team. Shape cross-functional collaboration and optimize operations for lasting customer satisfaction and rete...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$98K - $206K *

Join a dynamic team as you lead and mentor engineers to drive innovation in mission-critical software, AI/ML, or DevSecOps projects. Foster growth, manage workflow, and enhance engineering practices w...

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$114K - $252K *

Drive your career with innovative DevSecOps solutions enhancing cyber security for DOD/AF customers. Collaborate in an agile environment to develop cloud-native, identity management, and compliance-fo...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$91K - $169K *

Transform downstream biopharmaceutical processes by executing experiments, optimizing filtration, and collaborating cross-functionally to propel innovative therapeutics. Drive excellence in lab operat...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$209K - $239K *

Elevate product strategy and execution by leading cross-functional teams to develop innovative solutions that shape the future of enterprise software, transforming customer insights into impactful pro...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$109K - $125K *

Lead operational excellence by managing client relationships and supporting complex transactions. Drive projects for new product implementation while resolving escalated issues with strategic partners...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Business Services

$245K - $279K *

Drive impactful technical programs that shape products and platforms. Your leadership will harness complex technologies, fostering collaboration across teams to deliver innovative solutions aligned wi...

US-AnywhereRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$119K - $224K *

Transform your career by leading the design and implementation of Web and Email Security strategies for complex hybrid solutions, ensuring compliance, driving team objectives, and enhancing security i...

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$75K - $95K *

Champion customer relationships by delivering tailored financial solutions. Collaborate with teams to elevate the client experience and drive portfolio growth while maintaining compliance and managing...

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$147K - $215K *

Join a team that's dedicated to transforming customer operations through AI. You'll engage with strategic clients, translate their needs into advanced AI solutions, and ensure impactful deployments, d...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$100K - $145K *

Elevate your career by driving strategic initiatives and delivering impactful solutions that enhance operational efficiency and foster collaborative teamwork across business units...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Energy & Utilities

$100K - $130K *

Unlock potential by leading scientific content development and ensuring quality at a strategic level. Collaborate with teams, mentor junior staff, and drive impactful medical communication projects in...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $95K *

Optimize clinical trial processes by collaborating with site staff and investigators. Conduct monitoring visits to ensure protocol adherence, data integrity, and patient safety, contributing to the su...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What industries in Pennsylvania offer the most $100K+ jobs?question toggle

    There are numerous industries in Pennsylvania offering $100K+ jobs, including Tech, Finance, Healthcare, and more.

  • Can I find $100K+ jobs all over Pennsylvania on Ladders?question toggle

    Yes, Ladders list high-paying jobs in all areas of Pennsylvania including in big cities like Philadelphia and Pittsburgh, as well as smaller cities.

  • How often are the $100K+ job listings in Pennsylvania updated on Ladders?question toggle

    The $100K+ job listings in Pennsylvania are updated regularly to ensure that our users have access to the most current opportunities.