Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,459

Sort By: Relevance

$75K - $127K *

Transform software solutions by developing, analyzing, and optimizing applications. Collaborate with teams to enhance operational efficiency and deliver innovative technology for diverse industries in...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$62K - $103K *

Drive open-source research and analysis to support high-profile government clients. Conduct media monitoring, identify trends, and prepare concise reports to inform decision-making, all while working...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$92K - $200K *

Join a dynamic team as a Materials Research and Development Engineer, driving innovation in electronic materials and devices. Engage in R&D efforts, from materials growth to device fabrication, enhanc...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$92K - $200K *

Lead the charge in advancing semiconductor materials research and development. Collaborate with engineers to innovate processes for electronic devices, ensuring optimal performance through hands-on ex...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Join a team that's driving supply chain excellence by resolving critical issues, enhancing supplier performance, and ensuring production continuity through data-driven solutions and cross-functional c...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Aerospace & Defense

$240K - $253K *

Pioneer innovation in real-time bid optimization systems, driving advertising performance by turning complex mathematical insights into robust production code. Lead cross-functional initiatives to max...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$127K - $195K *

Join a team that's dedicated to optimizing customer investments in SAP Enterprise Cloud Services. As a trusted advisor, you'll enhance service delivery, drive continuous improvement, and ensure operat...

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$144K - $228K *

Empower the future of AI and HPC systems by leading digital ASIC design and strategic architecture for high-performance network interfaces, influencing product roadmaps and technology investments whil...

Today

  •   8 - 10 years exp.  •   Information Technology

$291K - $307K *

Innovate as you lead the Logistics product organization, shaping strategy and vision for sustainable growth while driving efficiencies that enhance the marketplace experience for customers, shoppers...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$231K - $244K *

Champion privacy initiatives by integrating compliance across product, engineering, and advertising teams. Ensure data protection measures are practical and actionable, positioning the organization as...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Consumer Technology

$149K - $157K *

Empower leaders by shaping talent strategies that connect business goals to people decisions. As a trusted advisor, drive organizational health and development while enhancing performance in a high-gr...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Consumer Technology

$98K - $157K *

Join us to source and close multi-location retail deals, building a new sales strategy for complex accounts. You'll navigate buyer dynamics, drive value-based selling, and collaborate with cross-funct...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Lead multi-discipline MEP projects, ensuring quality, budget, and timelines are met while fostering strong client relationships and managing internal teams effectively...

Today

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Lead innovative electrical design projects, ensuring quality and coordination across teams. Engage in all phases from concept to construction, leveraging your expertise to deliver exceptional results...

Today

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Drive technical excellence in aviation projects by leading system design and integration across telecom, IT, and security. Collaborate with stakeholders to ensure high-quality deliverables while mento...

Today

  •   8 - 10 years exp.  •   Business Services

$110K - $140K *

Shape the future of clinical research by ensuring compliance and quality in IVD studies. Collaborate with diverse teams to monitor sites, support patient safety, and uphold regulatory standards while...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Staffing

$140K - $150K *

Drive enterprise data architecture and cloud infrastructure strategies, enabling innovation and competitive advantage through advanced data solutions and emerging technologies. Collaborate with leader...

Today

  •   5 - 7 years exp.  •   Staffing

$90K - $110K *

Join a team that champions comprehensive pain management for Veterans, utilizing advanced clinical skills to assess, plan, and implement individualized care in a collaborative environment focused on i...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$137K - $154K *

Advance the future of healthcare coding by accurately assigning ICD-10 codes and MS-DRGs for inpatient records. Collaborate with clinical teams to ensure compliance and optimize reimbursement while ma...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$90K *

Elevate your career with a hands-on role in campaign operations and web management. Ensure timely campaign launches, accurate reporting, and effective audience targeting while collaborating with cross...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$210K - $275K *

Transform regulatory affairs in oncology by leading strategic submission initiatives and cross-functional collaborations, ensuring compliance and quality for impactful development programs. Drive regu...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$70K - $120K *

Grow your career with a dynamic sales role, engaging clients to deliver innovative pest solutions. Build relationships, achieve sales goals, and ensure safety while working independently in diverse en...

Today

  •   Less than 5 years exp.  •   Staffing

$206K - $277K *

Champion clinical trial success by leading operations and financial oversight for early-phase oncology studies. Drive process improvements and ensure compliance while collaborating with cross-function...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Shape the future of AI observability by leading product strategy, collaborating across teams, and driving the development of innovative solutions that empower engineers to enhance and optimize AI syst...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$150K *

Join our team to excel in consultative sales, meeting homeowners and providing tailored water treatment solutions. Leverage pre-qualified leads to build trust and deliver exceptional customer experien...

Today

  •   Less than 5 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.