Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.
Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.
Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.
Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.
Average Salary: $121,442
Senior Director, Commercial Analytics & Decision Science
$219K - $285K *
Shape and lead a centralized commercial analytics function, transforming complex data into actionable insights. Drive performance measurement, growth identification, and strategic decision-making acro...
1 week ago
Distinguished Engineer, AI Security Systems (Remote)
$235K - $350K *
Transform the future of cyber defense by architecting cutting-edge AI systems that autonomously protect against real-world threats. Lead technical direction, mentor teams, and drive innovation from re...
1 week ago
Engineer II - Site Reliability, Kubernetes (Remote, EST)
$100K - $145K *
Elevate your career by managing Kubernetes clusters across diverse environments. Collaborate with senior engineers to automate processes, troubleshoot issues, and enhance platform performance while de...
1 week ago
Sr. Manager, Application Engineering, WSS, Capital Solutions
$130K - $160K *
Play a key role in managing a team of engineers, fostering collaboration, and driving technical excellence in innovative chemical solutions while ensuring project efficiency and quality compliance...
Reposted 1 week ago
Associate Counsel, Employment and Commercial
$110K - $130K *
Collaborate with HR and legal teams to provide comprehensive employment law support, drafting and negotiating contracts while ensuring compliance with regulations. Balance legal risks with business ob...
1 week ago
Director, Field Analytics, Hematology
$174K - $234K *
Shape the future of Hematology analytics by leading strategic insights and performance initiatives. Collaborate with cross-functional teams to enhance field execution and drive commercial success thro...
1 week ago
Senior Clinical Research Associate - Oncology
$105K - $140K *
Lead the charge in monitoring clinical study sites, ensuring data integrity and patient safety while collaborating with diverse teams to enhance study delivery and compliance with regulatory standards...
Reposted 1 week ago
$74K - $124K *
Elevate compensation strategies by transforming complex data into actionable insights. Collaborate with stakeholders to manage compensation programs, analyze trends, and recommend solutions that ensur...
1 week ago
Vice President, Franchise Sales Development - Extended Stay
$485K *
Transform franchise growth in the Extended Stay sector by leading strategic initiatives, managing a team of Regional Vice Presidents, and building key relationships to enhance development opportunitie...
1 week ago
$162K - $207K *
Lead the charge in implementing and optimizing SAP Vistex solutions, translating business strategies into technical architecture while managing cross-functional teams and project deliverables for enha...
1 week ago
CIAM & IDAM Services & Enablement Lead
$129K - $185K *
Unlock potential by leading the Customer Identity & Access Management function, overseeing CIAM platform operations, and driving identity strategy across global digital ecosystems while collaborating...
1 week ago
Product Manager, Email Marketing
$120K - $135K *
Unlock potential by leading the technical architecture and roadmap for email marketing. Collaborate across teams to enhance platform capabilities, ensuring effective audience targeting and reliable de...
1 week ago
Professional (Senior) Sales Representative, Pain - New Orleans W, LA
$100K - $162K *
Unlock potential by developing effective strategies and relationships to drive sales growth in the territory, ensuring compliance with regulations and high levels of customer engagement through effect...
Reposted 1 week ago
$75K - $105K *
Lead and elevate the customer experience while managing daily operations of the Collision Center. Drive performance through effective coaching, budget management, and adherence to quality standards, e...
1 week ago
Senior Credit Workout Officer IV
$115K - $135K *
Lead the charge in managing complex credit workouts, evaluating borrower plans, and negotiating exit strategies while ensuring compliance and integrity in loan documentation and processes...
1 week ago
Product Builder, Merchant Portal
$104K - $145K *
Elevate product development by defining, designing, and prototyping features for a merchant portal, leveraging AI tools and user feedback to enhance payment processing solutions rapidly and effectivel...
1 week ago
Sr. Analyst, Pricing Analytics
$89K - $134K *
Explore your potential as a key analytical consultant, leveraging data to optimize drug pricing and enhance pharmacy relationships while collaborating across multiple functions to drive strategic grow...
1 week ago
Manager, IT Delivery – IAM/IGA Engineering
$120K - $145K *
Engage in leading a dynamic team to enhance IAM/IGA capabilities, ensuring secure access and operational excellence while driving automation and collaboration across technology and business stakeholde...
1 week ago
$110K - $130K *
Drive innovative digital financial solutions by leading product management efforts, collaborating with cross-functional teams, and enhancing user experiences to empower participants in their financial...
1 week ago
Director, AI Platforms & Engineering
$105K - $165K *
Shape the future of AI platforms by leading strategy, architecture, and engineering for scalable, secure solutions. Drive innovation while ensuring compliance and operational excellence across enterpr...
1 week ago
Neurology Territory Business Manager (Overlay), Philadelphia
$140K - $192K *
Drive your career with a dynamic team focused on neurology sales. Collaborate with healthcare professionals and internal partners to exceed launch objectives and enhance patient care in your territory...
1 week ago
Neurology Territory Business Manager (Overlay), Philadelphia
$140K - $192K *
Shape the future of neurology sales by collaborating with healthcare professionals and driving demand generation. Leverage your expertise to meet launch objectives and enhance patient care through str...
1 week ago
$136K - $187K *
Lead patient education and support initiatives for individuals affected by generalized Myasthenia Gravis. Collaborate with caregivers and healthcare teams to enhance treatment coordination and empower...
1 week ago
$136K - $187K *
Join a team that's dedicated to empowering patients with generalized Myasthenia Gravis through education and support. As a key point of contact, you'll coordinate care, provide resources, and ensure c...
1 week ago
Neurology Territory Business Manager (Overlay), Philadelphia
$140K - $192K *
Empower healthcare professionals by driving demand in the Neurology Franchise. Collaborate with local teams to execute strategies, support launches, and exceed sales objectives while maintaining a pat...
1 week ago
What types of $100K+ jobs can I find in Pennsylvania?
Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.
Are these Pennsylvania jobs vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.
Can I find remote or hybrid jobs in Pennsylvania?
Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.