Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.
Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.
Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.
Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.
Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.
Average Salary: $121,459
Principal Scientist/Associate Director, Translational Medicine
$190K - $210K *
Collaborate with cross-functional teams to drive clinical biomarker strategy and execution, translating discovery insights into actionable approaches that enhance patient outcomes in early neuroscienc...
1 week ago
$80K - $95K *
Take ownership of payroll operations, ensuring accuracy and compliance while leading a team to deliver timely wage payments and manage tax obligations effectively across the organization...
1 week ago
Business Technology Solutions Manager
$120K - $145K *
Accelerate progress at the forefront of digital transformation by leading high-impact Microsoft initiatives. Drive adoption of AI and low-code solutions, manage cross-functional teams, and shape strat...
1 week ago
Life Sciences Data Management, Senior (MDM/DGov)
$116K - $229K *
Transform commercial operations by leveraging AI and analytics to drive innovative solutions for Life Sciences clients. Collaborate with high-performing teams to enhance data-driven decision-making an...
1 week ago
Life Sciences Data Management, Senior (MDM/DGov)
$116K - $229K *
Innovate data-driven solutions for Life Sciences, leveraging AI and analytics to transform commercial operations. Collaborate with teams to deliver insights and optimize strategies for pharma clients...
1 week ago
$126K - $158K *
Lead sales operations to drive revenue growth and optimize team performance. Oversee planning, forecasting, and reporting while ensuring alignment with organizational goals. Collaborate with cross-fun...
1 week ago
$90K - $130K *
Manage visual inspection operations, ensuring compliance with safety and quality standards while driving efficiency and team performance. Lead investigations and audits, fostering a culture of continu...
1 week ago
$126K - $158K *
Unlock potential by leading sales operations to drive revenue growth and team productivity. Collaborate with cross-functional leaders to optimize strategies, enhance performance, and ensure alignment...
1 week ago
Bilingual Strategic Cuisines Flex Account Executive (Thai)
$128K - $205K *
Engage with Thai Cuisine restaurants to drive growth through consultative sales. Utilize your bilingual skills to convert leads, conduct demos, and build relationships, ensuring a tailored experience...
1 week ago
Principal SAP Retail POS Consultant
$145K - $180K *
Transform retail operations by serving as the primary SAP POS expert for DoD S/4HANA implementations, ensuring alignment with operational goals and financial reporting while bridging technical teams a...
1 week ago
Communication Evaluation Research Project Director
$160K - $185K *
Unlock your potential as a Project Director, leading innovative health research initiatives. Drive strategic planning and capture opportunities while managing a dynamic team to tackle complex public h...
1 week ago
Hematology Oncology Pharmacy Manager
$110K - $130K *
Redefine pharmaceutical care by managing staff and overseeing medication processes. Ensure quality, safety, and cost-effectiveness in drug therapy while collaborating with healthcare professionals to...
1 week ago
Utilities Vulnerability Assessment Engineer
$63K - $111K *
Empower mission success by assessing utility vulnerabilities and enhancing infrastructure resilience against diverse threats. Collaborate with a multidisciplinary team to ensure operational continuity...
1 week ago
Associate Director / Senior Managing Consultant - Financial Services Operations & Technology
$150K - $250K *
Transform financial services by leading complex banking operations and technology projects. Collaborate with clients to enhance performance, drive innovation, and shape a new practice within a dynamic...
1 week ago
$99K - $165K *
Transform sourcing strategies by leading initiatives across key spend categories, collaborating with stakeholders to optimize supplier performance, mitigate risks, and drive cost savings while ensurin...
1 week ago
$137K - $245K *
Shape the future of physical operations by driving AI-powered product innovation. Collaborate across teams to identify customer needs, prototype solutions, and deliver impactful products that enhance...
1 week ago
NG, NGLs, and Specialties Optimization Modeling & Technology Manager
$162K - $243K *
Elevate your career by leading the development of optimization models and digital tools that enhance decision-making across the NG & NGL value chain, collaborating with cross-functional teams to drive...
1 week ago
$65K - $99K *
Execute geotechnical field and lab testing for infrastructure projects, ensuring compliance with safety and quality standards. Collaborate with senior technicians and engineers to support drilling ope...
1 week ago
$110K - $130K *
Shape the future of healthcare by leading complex implementations across provider and payor organizations. Drive project success through collaboration, strategic planning, and innovative solutions whi...
1 week ago
Medical Safety Manager, Ambulatory Monitoring & Diagnostics
$133K - $237K *
Contribute to patient safety by overseeing medical product surveillance, analyzing data, and ensuring compliance with regulations. Collaborate on risk management and support clinical studies to enhanc...
1 week ago
$102K - $184K *
Elevate your career by leading market-level financial reporting and performance management in value-based healthcare. Collaborate with stakeholders to drive insights and outcomes, ensuring disciplined...
1 week ago
$95K - $115K *
Shape the future of manufacturing operations by leading cross-departmental initiatives, optimizing processes, and driving efficiency. Collaborate with teams to implement policies and achieve organizat...
1 week ago
Director - Private Pay Business
$110K - $130K *
Lead and coordinate business development, customer relations, and quality management activities to enhance private pay services, ensuring operational excellence and growth in a dynamic healthcare envi...
1 week ago
$110K - $130K *
Champion privacy solutions by engaging with clients, delivering tailored demos, and driving sales success. Leverage your expertise to influence product development and navigate the intersection of AI...
1 week ago
Director ( Commercial Due Diligence)
$230K - $300K *
Elevate your career by leading commercial due diligence engagements, partnering with corporate and private equity clients to assess growth potential and risks. Drive insights that influence strategic...
1 week ago
What kinds of high-paying jobs can I find in Pennsylvania?
Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.
Do Pennsylvania jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.
How can I narrow my search for jobs in Pennsylvania?
Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.
Are remote or hybrid jobs available in Pennsylvania?
Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.