Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$115K - $140K *

Drive operational excellence in commercial readiness and support cross-functional teams to ensure effective execution of launch strategies and operational priorities in a dynamic biotech environment...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$225K - $275K *

Optimize quality assurance processes to ensure compliance with regulatory standards and drive improvements across all operations. Lead a talented team to establish and maintain an effective Quality Ma...

United StatesRemote

Reposted 6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$132K - $207K *

Elevate your career by driving growth in the mortgage industry, partnering with top lenders to enhance FICO's analytics solutions. Lead strategic initiatives, foster client relationships, and deliver...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$200K - $225K *

Transform marketing strategies to drive growth and engagement across public and private sectors. Lead integrated marketing efforts, brand positioning, and customer marketing services while leveraging...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$157K - $256K *

Shape strategic pricing and channel strategies for innovative therapies, ensuring patient access and affordability. Lead cross-functional initiatives, optimize distribution models, and drive market in...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive strategic sourcing initiatives by leading supplier negotiations and managing relationships globally. Shape category strategies to optimize cost, quality, and delivery performance while ensuring...

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Empower decision-making by transforming spend data into actionable insights. In this role, you'll develop dashboards, analyze procurement data, and collaborate with teams to enhance visibility and dri...

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Transform sourcing operations by leveraging AI and automation tools. Collaborate with teams to enhance workflows, enforce governance, and drive efficiency through innovative solutions, ensuring compli...

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $182K *

Accelerate growth by driving new software sales, building client relationships, and tailoring solutions to meet unique business needs. Collaborate with cross-functional teams to ensure a seamless cust...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Accelerate project delivery by managing construction activities, ensuring budget adherence, and maintaining client communication. Oversee multiple commercial refrigeration projects while fostering tea...

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$90K - $119K *

Lead the evaluation, design, and rehabilitation of bridge structures, ensuring compliance with design codes while collaborating with a dynamic team to deliver innovative solutions and enhance transpor...

6 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$85K - $105K *

Optimize regulatory compliance processes for a multi-state transportation network. Collaborate cross-functionally to ensure operational readiness and manage ongoing compliance across diverse markets...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$152K - $221K *

Shape the future of product innovation by leading cross-functional teams to develop and enhance solutions that meet customer needs, drive satisfaction, and align with organizational goals in a dynamic...

6 days ago

  •   5 - 7 years exp.  •   Business Services

$168K - $210K *

Transform pricing strategies by leading cross-functional teams to enhance decision-making and model deployment. Drive the evolution of pricing platforms, integrating advanced AI to streamline workflow...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $150K *

Elevate your career by driving enterprise sales for innovative solutions. Engage with multinational accounts, build strategic relationships, and lead complex negotiations to unlock growth opportunitie...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Join a team that's dedicated to delivering exceptional project implementations and enhancements for restaurant brands. Lead cross-functional efforts, ensuring customer satisfaction while managing time...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$150K - $180K *

Shape strategic sales initiatives targeting Fortune 2000 accounts. Drive complex sales cycles, engage with C-suite leaders, and leverage AI solutions to meet revenue goals while building a robust pipe...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Unlock potential by collaborating with public safety agencies to design and implement solutions that enhance operational efficiency. Join a dynamic team focused on delivering impactful software config...

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Lead quality assurance initiatives and drive continuous improvement in a hands-on manufacturing environment. Collaborate with production teams to ensure compliance with quality standards and enhance o...

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Empower quality assurance by developing AI-assisted automated tests, integrating them into CI/CD pipelines, and collaborating with cross-functional teams to enhance software reliability and release ef...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$59K - $118K *

Drive revenue growth by managing customer accounts and pursuing new sales opportunities. Utilize consultative strategies to build relationships and meet sales quotas while serving as a trusted advisor...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Lead a dynamic team as a Clinic Director, driving clinical excellence and operational success while enhancing patient outcomes and fostering a culture of growth in a collaborative environment...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$114K - $167K *

Engineer innovative ERP solutions by analyzing complex business processes, defining architecture, and leading integration efforts to optimize performance and ensure compliance. Drive impactful customi...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$76K - $129K *

Join us to build strong relationships with key policyholders through proactive communication and skilled negotiation. You'll bridge clients and the home office, tackling concerns and driving improveme...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Empower project success by coordinating engineering activities across diverse construction sites. Collaborate with teams to ensure safety, quality, and timely execution of projects in energy and aeros...

6 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.