Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$77K - $202K *

Engage in enterprise risk management as a Senior Associate, supporting internal audits and controls. Build client relationships, mentor juniors, and leverage technology to enhance governance and risk...

6 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$140K - $180K *

Elevate customer insights by translating data into actionable product capabilities. Collaborate with cross-functional teams to prioritize initiatives, enhance marketing performance, and leverage AI fo...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$94K - $122K *

Join a dynamic finance team to drive strategic planning, oversee operations, and influence key business decisions. Leverage your expertise to enhance financial performance and lead high-performing tea...

6 days ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$168K - $240K *

Lead the charge in optimizing business operations through innovative solutions, driving efficiency and productivity while fostering cross-functional collaboration and data-driven decision-making to en...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Information Technology

$207K - $300K *

Drive reliability and performance in large-scale systems by leading innovative infrastructure projects and collaborating with development teams to enhance Google Ads services and ensure optimal uptime...

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Engineer robust security solutions by assessing web applications and APIs. Leverage your expertise in OWASP and SANS frameworks to identify vulnerabilities, conduct thorough testing, and enhance secur...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$93K - $155K *

Transform the future of Federal contract administration by advising account teams, managing high-value subcontracts, and driving strategic negotiations. Leverage your expertise to enhance compliance a...

6 days ago

  •   8 - 10 years exp.  •   Business Services

$100K - $120K *

Unlock potential by partnering with ABA practice owners to enhance operations, drive growth, and improve performance. Collaborate closely with providers to navigate challenges and implement strategic...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$93K - $155K *

Lead strategic subcontract management efforts, advising teams on Federal contract administration. Handle complex subcontracts impacting revenue, ensuring compliance and accuracy while fostering collab...

6 days ago

  •   8 - 10 years exp.  •   Business Services

$85K - $105K *

Join us to analyze and adjudicate complex workers compensation claims, delivering innovative solutions in a dynamic environment. Collaborate with clients across industries while enjoying professional...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $108K *

Champion innovative solutions by configuring Salesforce Marketing Cloud, automating customer processes, and collaborating with teams to enhance client engagement through data-driven insights and effec...

6 days ago

  •   Less than 5 years exp.  •   Business Services

$90K - $132K *

Lead the charge in managing and expanding customer relationships across diverse industries, driving new business opportunities and delivering tailored solutions that enhance operational efficiency and...

Pennsylvania, USRemote

6 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$150K - $180K *

Drive product strategy and execution for a critical portfolio area, leading cross-functional teams to transform user insights into impactful software solutions while mentoring others and shaping platf...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Lead the charge in shaping product marketing strategies that drive adoption and pipeline. Collaborate with cross-functional teams to craft compelling narratives and ensure our differentiated value res...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$80K - $95K *

Lead the charge in neurodiagnostic services, overseeing operations, guiding staff, and ensuring high-quality patient care while collaborating with healthcare professionals to enhance service delivery...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Optimize patient outcomes by collaborating with healthcare teams to provide expert oncology pharmacotherapy, ensuring safe medication management and education across multiple pharmacy locations with a...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$130K - $140K *

Elevate your career by joining a dynamic team to design and implement innovative cloud solutions in a multi-cloud environment, ensuring scalability, security, and alignment with business objectives wh...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$162K - $203K *

Champion scientific engagement by building relationships with key opinion leaders in Urology and Women's Health. Leverage expertise to support medical strategies and enhance product knowledge across t...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Elevate employee experiences by designing and implementing HR solutions. Lead technical projects, optimize integrations with Microsoft 365, and mentor developers to enhance ServiceNow capabilities and...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$85K - $95K *

Accelerate progress at drug development by leading bioanalytical studies, optimizing methods, interpreting data, and collaborating with teams to enhance innovative therapies for patients...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Empower patient care by ensuring safe and effective drug therapy through accurate dispensing, monitoring, and education, while collaborating with healthcare providers to enhance pharmacotherapy practi...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Champion the growth of our commercial engine by leading business development efforts, forging strategic partnerships, and driving revenue as quantum computing transitions to enterprise applications. C...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $185K *

Architect comprehensive clinical supply strategies for global trials. Collaborate across functional teams to secure timely, compliant drug supply while managing risks and inventory effectively, ensuri...

United StatesRemote

Reposted 6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$115K - $140K *

Drive operational excellence in commercial readiness and support cross-functional teams to ensure effective execution of launch strategies and operational priorities in a dynamic biotech environment...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$225K - $275K *

Optimize quality assurance processes to ensure compliance with regulatory standards and drive improvements across all operations. Lead a talented team to establish and maintain an effective Quality Ma...

United StatesRemote

Reposted 6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.