Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$120K - $145K *

Optimize financial leadership and performance management across Consulting and Supply Chain. Collaborate with teams to drive budgeting, forecasting, and profitability analysis while ensuring complianc...

6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Join a dynamic team to architect and implement a next-gen Design System, ensuring consistent, accessible experiences across products. Collaborate with cross-functional teams to drive technical alignme...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$110K - $130K *

Grow your career with a leadership role focused on pharmacy operations, team management, and clinical safety. Drive performance and operational excellence while ensuring compliance in a dynamic, fast...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$103K - $146K *

Join a team that's dedicated to delivering exceptional patient care through precise prescription management and clinical consultations, ensuring compliance with regulations while optimizing pharmacy o...

6 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$201K - $251K *

Elevate access strategies and marketing initiatives for oncology products, focusing on non-clinical value propositions. Collaborate cross-functionally to ensure successful product launches and effecti...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Engineer and manage large capital equipment projects, ensuring effective budgeting, design, and team collaboration. Mentor junior engineers while maintaining safety and compliance standards in a dynam...

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$255K - $424K *

Lead the development and execution of Immunology access services strategy, ensuring seamless patient and provider experiences. Collaborate cross-functionally to enhance reimbursement initiatives and d...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$142K - $160K *

Champion privacy compliance in the Neurology therapeutic area, providing expert guidance on data protection, contract negotiation, and training. Collaborate with cross-functional teams to ensure adher...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $150K *

Drive growth in oral surgery practices by building relationships, pursuing new sales opportunities, and achieving targets. Leverage your sales expertise to deliver exceptional customer service and sup...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $500K *

Unlock potential by driving mortgage transactions with innovative technology and dedicated support. Leverage robust investor access for swift approvals and closings. Ideal for experienced professional...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$78K - $119K *

Help us shape the future of transportation in Pennsylvania by leading statewide planning initiatives. This role involves overseeing data integrity, managing programs, and guiding a team to enhance tra...

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$78K - $119K *

Lead the charge in managing energy and mineral resources on state lands. Oversee staff, guide contract negotiations, and conduct resource evaluations while collaborating with agency partners to ensure...

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$78K - $119K *

Join a dynamic team to oversee operations and development at a historic museum, ensuring preservation, education, and community engagement while managing staff and resources effectively for a sustaina...

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$69K - $104K *

Empower public health initiatives by leading organ donation programs, collaborating with partners, and enhancing community outreach. Drive program evaluation and policy development to improve health o...

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$69K - $104K *

Unlock potential by managing the Title IV-A grant program, ensuring compliance and effective resource allocation while supporting educational initiatives and providing training and technical assistanc...

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$69K - $104K *

Launch your career as an Audit Specialist 3, leading audit engagements to ensure compliance and accountability in public funds. Collaborate with teams, assess risks, and prepare reports that enhance f...

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $110K *

Design and develop advanced analytics solutions, transforming complex healthcare data into actionable insights using Azure Databricks and Power BI. Collaborate with cross-functional teams to enhance r...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$87K - $89K *

Elevate young learners by providing specialized instruction and support tailored to individual needs, fostering growth and development through collaboration with families and educational teams...

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Optimize production efficiency and safety across multiple manufacturing sites, leading teams to meet performance standards and compliance while driving continuous improvement and operational excellenc...

6 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$110K - $130K *

Join us to minimize access barriers for patients and providers, executing market access plans across multiple states. Collaborate with healthcare professionals to resolve reimbursement issues and enha...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $350K *

Join a team that's building scalable, high-performance backend systems using TypeScript. Collaborate across functions to optimize trading solutions and tackle complex challenges in the blockchain spac...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$76K - $119K *

Drive high-quality delivery of Data & AI products by leading cross-functional teams, ensuring alignment with strategic priorities, and optimizing execution processes for maximum business impact...

Conshohocken, PARemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$76K - $119K *

Lead cross-functional Data & AI product teams to ensure efficient delivery, risk management, and alignment with strategic priorities, driving targeted business value through effective execution and co...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Empower your career by leading the design and implementation of Oracle Field Service solutions for utility organizations. Collaborate with stakeholders to enhance operational performance and customer...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Staffing

$80K - $95K *

Drive excellence in field-based engineering services, ensuring optimal performance and reliability of industrial automation systems through maintenance, troubleshooting, and customer engagement...

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.