Find Your Next High-Paying Job in Pennsylvania

Are you a professional seeking $100K+ jobs in Pennsylvania? You've come to the right place. Ladders is your hub for high-paying Pennsylvania jobs across a broad range of industries, including Tech, Finance, Healthcare, and more.

Unlock Opportunities in Pennsylvania

Pennsylvania, known for its rich history and diverse job market, offers a plethora if opportunities for ambitious professionals seeking high-paying jobs.

How Ladders Can Help

Whether you're looking for jobs in Philadelphia, Pittsburgh, or smaller cities within Pennsylvania, Ladders has got you covered. Our selection of $100K+ jobs in Pennsylvania is carefully curated and regularly updated. Start your job searc on Ladders today!

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $120,902

Sort By: Relevance

$100K - $130K *

Empower clients by designing AI-driven data solutions that enhance government services, utilizing your expertise in data engineering, NLP, and machine learning to drive impactful mission outcomes and...

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$200K - $250K *

Lead a dynamic Pediatric Neurology Division committed to clinical excellence, education, and research. Collaborate with esteemed faculty and foster innovative approaches to enhance pediatric care, men...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$64K - $122K *

Partner with us to drive equipment finance solutions, enhance revenue growth, and manage complex transactions while collaborating across teams in a dynamic environment. Your efforts will influence out...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $110K *

Join a team that's dedicated to ensuring sales compensation accuracy and operational excellence. You'll collaborate with cross-functional teams to enhance processes, support Xactly implementation, and...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$105K - $155K *

Shape the future of data analytics by driving strategic initiatives and analyzing fraud vectors. Collaborate cross-functionally to deliver impactful solutions while using data-driven experimentation f...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$150K - $200K *

Lead the evolution of investment operations to create a resilient, high-performing environment. Oversee complex portfolios, drive strategic partnerships, and enhance operational strategies to ensure s...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $130K *

Lead and develop a high-performing accounting team, ensuring financial accuracy and compliance within a dynamic construction environment. Collaborate with senior leadership to drive strategic initiati...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$85K - $106K *

Advance fusion energy policy by conducting research, developing strategies, and engaging with key stakeholders across U.S. and European contexts. Collaborate with teams to drive advocacy efforts, ensu...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$70K - $90K *

Manage and enhance team performance by driving safety, quality, and customer satisfaction across processing workflows. Collaborate with key departments to ensure operational excellence while fostering...

1 week ago

  •   Less than 5 years exp.  •   Transportation

$60K - $120K *

Empower customers by driving sales through prospecting, demos, and account management. Collaborate within a team environment to grow revenue in the Automotive/Transportation industry while achieving s...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $110K *

Join a team that's dedicated to maintaining and optimizing SQL Server environments, ensuring security and performance. Collaborate with development teams on tasks like query optimization and provide c...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$91K - $185K *

Optimize application security by executing manual code reviews and vulnerability assessments, collaborating with development teams to enhance security practices and integrating SAST tools into CI/CD w...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$244K - $305K *

Tackle advanced machine learning innovations to enhance guest and host experiences. You will lead the development of scalable AI systems, driving impactful solutions in messaging and notifications whi...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Consumer Technology

$175K - $334K *

Unlock potential by leading the development of transformative digital solutions. Drive innovation and enhance user experiences across various platforms and channels, collaborating with cross-functiona...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$120K - $150K *

Transform data processes with your expertise in cloud data pipelines, bridging OT/IT systems, and driving efficiency in manufacturing environments. Leverage your advanced SQL and Python skills to enha...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$135K *

Join a high-impact trauma hospital team, operating Siemens equipment while ensuring patient safety and comfort during diagnostic imaging. Gain invaluable experience in a globally recognized organizati...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$117K - $201K *

Shape the future of Drug Product Development by leveraging data science to build AI-driven decision intelligence tools, driving strategic planning and operational efficiency across therapeutic develop...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $95K *

Shape the future of local business financing by forging relationships, analyzing lending opportunities, and driving growth in a dynamic commercial lending environment...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$106K - $177K *

Oversee and enhance customer success strategies by leading a high-performing team of Customer Success Managers. Drive customer satisfaction, retention, and operational excellence through effective coa...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$117K - $201K *

Pioneer advanced data science strategies to enhance decision-making in therapeutics development. Collaborate with cross-functional teams to create digital twin models and decision intelligence tools t...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $110K *

Explore a rewarding Senior Clinical Research Associate role managing relationships and ensuring quality in clinical trials across various therapeutic areas, with a strong focus on patient safety and c...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$104K - $156K *

Pioneer effective logistics management by leading teams to enhance operations, drive improvements, and ensure compliance. Utilize your expertise in financial oversight and workforce development to ach...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$107K - $166K *

Help us enhance healthcare engagement by providing expert support to HCPs, leveraging digital tools for outreach, and collaborating with teams to elevate patient care and insights, all while driving s...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$149K - $199K *

Lead the charge in optimizing enterprise content platforms, enhancing scalability and compliance. Drive strategic initiatives for content automation, modular adoption, and PRC/MRC process improvements...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Unlock potential by defining and leading global equity services, enhancing operational efficiency, and ensuring scalable, resilient support for investment strategies while driving transformational ini...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What industries in Pennsylvania offer the most $100K+ jobs?question toggle

    There are numerous industries in Pennsylvania offering $100K+ jobs, including Tech, Finance, Healthcare, and more.

  • Can I find $100K+ jobs all over Pennsylvania on Ladders?question toggle

    Yes, Ladders list high-paying jobs in all areas of Pennsylvania including in big cities like Philadelphia and Pittsburgh, as well as smaller cities.

  • How often are the $100K+ job listings in Pennsylvania updated on Ladders?question toggle

    The $100K+ job listings in Pennsylvania are updated regularly to ensure that our users have access to the most current opportunities.