Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$225K - $275K *

Champion investment product distribution strategies and manage key relationships. Lead a team to develop tailored solutions, drive business growth, and ensure compliance with industry regulations whil...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$95K - $115K *

Lead and manage bridge inspection operations across Central and Eastern PA, driving business development, staff mentorship, and financial success while fostering client relationships and ensuring comp...

5 days ago

  •   8 - 10 years exp.  •   Technical Services

$218K - $256K *

Elevate compliance operations by architecting AI systems that automate workflows, ensuring accuracy and regulatory adherence while mentoring engineers and driving technical excellence in machine learn...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $172K *

Join a dynamic Sales team to develop key relationships and strategic account plans. Engage with C-suite executives, drive solutions to meet clients' goals, and leverage your problem-solving skills for...

RemoteRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Information Technology

$210K - $250K *

Join a team that's dedicated to providing comprehensive medical care, ensuring high-quality, cost-effective treatment for patients in both practice and hospital settings while participating in quality...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $140K *

Transform your career by leading Business Central ERP implementations. Collaborate with clients and teams to deliver tailored solutions, ensuring project success from kickoff to go-live. Drive innovat...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$171K - $246K *

Shape the future of mental health care by providing remote psychiatric assessments and treatments. Deliver compassionate support to diverse clients, focusing on adults and adolescents, while collabora...

RemoteRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $150K *

Advance innovative therapeutic programs targeting genetically driven diseases through strategic sourcing, relationship building, and cross-functional collaboration, ensuring a patient-first approach i...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$137K - $235K *

Elevate decision-making by leading the development of Operations Research and Decision Intelligence solutions. Collaborate with senior stakeholders to enhance forecasting, optimization, and simulation...

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$137K - $235K *

Join a team that's redefining decision intelligence in pharmaceutical R&D. Lead the development of advanced modeling solutions, collaborating with senior stakeholders to enhance operational efficiency...

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$137K - $235K *

Drive innovation in data science by developing advanced decision-support models that enhance operational efficiency and strategic planning across therapeutic development and supply chains, collaborati...

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Empower our team by ensuring the operational excellence of a cloud-based application platform. Collaborate with cross-functional teams to monitor performance, troubleshoot issues, and support software...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $150K *

Lead the charge in advancing our mission through strategic fundraising and resource development. Collaborate with leadership to foster a culture of philanthropy, ensuring sustainable funding and impac...

5 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$90K *

Unlock your potential as a Board Certified Behavior Analyst, leading clinical initiatives and shaping innovative programming for children. Collaborate with a dedicated team to enhance service delivery...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$105K - $160K *

Empower channel partners by providing technical leadership and solution architecture expertise focused on HPE Aruba technologies. Drive sales engagement and architect resilient infrastructure solution...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$138K - $240K *

Join a team that's driving supplier program execution and partner growth. Lead sales strategies, manage a high-performing team, and cultivate key relationships to achieve ambitious sales goals in the...

RemoteRemote

5 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$102K - $187K *

Lead the charge in strategic supplier management, driving growth and operational excellence through executive engagement, market development, and partner ecosystem initiatives while mentoring teams an...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$78K - $125K *

Accelerate progress at developing new accounts in the Aerospace & Defense sector. Engage with venture-capital-backed companies, convert leads, and build strategic relationships to drive sales and maxi...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$280K - $400K *

Empower engineering excellence by leading a growing team to deliver high-quality software solutions while fostering collaboration across teams and ensuring operational scalability...

United StatesRemote

Reposted 5 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Lead the charge in developing impactful learning strategies that enhance employee skills and drive business outcomes. Collaborate with stakeholders to identify needs, implement solutions, and ensure c...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$80K - $95K *

Champion growth by developing and maintaining dealer partnerships, driving sales, and enhancing customer satisfaction in the auto finance sector. Leverage market insights to optimize performance and e...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$132K - $245K *

Transform Sales Operations by leading strategic initiatives that enhance efficiency, drive automation, and leverage AI. Collaborate with clients to redefine their operational models, ensuring improved...

5 days ago

  •   8 - 10 years exp.  •   Business Services

$132K - $245K *

Lead the charge in transforming Sales Operations through innovative strategies, automation, and AI. Collaborate with clients to enhance efficiency, drive revenue, and redefine operational models for a...

5 days ago

  •   8 - 10 years exp.  •   Business Services

$76K - $91K *

Help us enhance lives by providing compassionate nursing care in a supportive community. Join our dedicated team to ensure residents receive exceptional care and support, fostering a safe and enrichin...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$157K - $283K *

Elevate your career by managing complex R&D projects in wireless communication, focusing on 6G security for military applications. Collaborate with multidisciplinary teams to deliver innovative soluti...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.