Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,442

Sort By: Relevance

$80K - $95K *

Empower the design and implementation of automation systems while leading smaller projects, providing technical guidance, and ensuring project alignment with client expectations under general supervis...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $130K *

Develop and optimize a scalable, geo-distributed database solution while leading a skilled team. Engage in deep technical challenges to enhance performance and reliability across diverse environments...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Join a team that's dedicated to ensuring timely delivery of critical data center capacity. Collaborate cross-functionally to manage equipment logistics and resolve delivery challenges across a regiona...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$140K - $180K *

Transform enterprise relationships by driving sales, managing pipelines, and exceeding quotas with existing and new MariaDB services. Collaborate across teams to deliver tailored solutions in a fast-p...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$500K+*

Explore a rewarding opportunity as a fellowship-trained Interventional Radiologist, supporting growth in a well-respected practice. Enjoy modern technology, competitive compensation, and a collaborati...

Today

  •   Less than 5 years exp.  •   Healthcare

$121K - $154K *

Join a team that's dedicated to delivering exceptional financial due diligence services, empowering clients through middle-market transactions while optimizing value and ensuring comprehensive support...

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$170K - $190K *

Drive cloud engineering excellence by designing Azure environments, leading enterprise cloud adoption, and shaping standards for a high-impact team focused on hybrid infrastructure and transformation...

Reposted today

  •   Less than 5 years exp.  •   Staffing

$110K - $130K *

Transform your career by leading hotel operations across a diverse portfolio. Drive performance, enhance guest satisfaction, and develop leadership talent while ensuring operational excellence and bra...

Today

  •   5 - 7 years exp.  •   Hospitality & Recreation

$92K - $167K *

Unlock potential by developing and maintaining scalable applications, integrating new technologies, and participating in Agile methodologies to enhance product features and client solutions...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$121K - $231K *

Deliver innovative signal processing solutions by developing and validating sonar algorithms. Collaborate with experts to enhance military applications, analyze performance, and support field testing...

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$121K - $231K *

Engage in the development and analysis of sonar signal processing algorithms, collaborating with experts to innovate solutions for military applications. Contribute to technical documentation and supp...

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$99K - $120K *

Join our innovative team to architect and deliver cutting-edge IoT systems for special projects. You'll drive initiatives from concept to field pilot, integrating advanced technologies in a dynamic, c...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Technical Services

$158K - $166K *

Join a team that's optimizing product data infrastructure to enhance customer trust and accessibility. You'll lead cross-functional initiatives that drive the strategy for catalog attributes, ensuring...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Consumer Technology

$102K - $204K *

Bring your expertise to optimize procurement processes, enabling scalable and compliant operations. Collaborate across departments and lead digital transformations to enhance efficiency and user adopt...

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$128K - $135K *

Champion data-driven decisions as you build reporting infrastructure and analytical frameworks that empower GTM leaders and external partners with timely insights and actionable strategies to fuel bus...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Consumer Technology

$125K - $150K *

Elevate your career by leading security intelligence across the Americas. Shape strategic insights, guide crisis responses, and mentor a high-performing team while collaborating with global experts to...

Today

  •   11 - 15 years exp.  •   Healthcare

$80K - $95K *

Elevate culinary excellence by leading a dynamic team, managing budgets, and enhancing guest experiences across multiple dining venues in a fast-paced resort environment. Drive innovation and foster c...

Today

  •   5 - 7 years exp.  •   Hospitality & Recreation

$132K - $338K *

Shape your career by leading cybersecurity innovation in the Utilities sector, driving strategic transformation that enhances operational resilience and maintains compliance across diverse utility env...

Reposted today

  •   8 - 10 years exp.  •   Business Services

$77K - $95K *

Lead the charge in optimizing client websites through strategic SEO initiatives, fostering client relationships, and driving growth opportunities while mentoring junior staff and collaborating with a...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$230K - $368K *

Grow your career with a dynamic team that builds innovative solutions across full stack, focusing on customer needs and delivering impactful results in a fast-paced, startup-like environment...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$190K - $304K *

Champion product growth by guiding strategy and development from MVP to scale. Collaborate with cross-functional teams to deliver clear, impactful solutions, while continuously refining based on custo...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$183K - $293K *

Contribute to a cutting-edge global privacy program, ensuring compliance with regulations while driving innovative privacy solutions. Collaborate across teams to manage risk and enhance privacy practi...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Enterprise Technology

$190K - $304K *

Lead the charge in shaping a dynamic consumer brand experience that resonates across all touchpoints. Collaborate with cross-functional teams to create a cohesive identity that engages millions of din...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Enterprise Technology

$132K - $302K *

Transform the future of Financial Services by architecting enterprise-scale Data 360 and AI solutions. Lead technical design, governance, and client engagement across Banking, Capital Markets, and Ins...

Today

  •   8 - 10 years exp.  •   Business Services

$140K - $200K *

Join a dynamic team and lead safety compliance for autonomous vehicles. This senior role requires expertise in regulatory engagement, documentation, and safety assurance. Drive industry standards, ens...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.