Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,521

Sort By: Relevance

$147K - $220K *

Optimize project delivery by leading clinical study initiatives, ensuring quality, budget, and timelines are met. Collaborate with teams and clients to drive success in complex global trials while man...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $140K *

Unlock potential by translating complex scientific data into clear, impactful communication. Collaborate across teams to shape strategy and elevate medical communications that enhance patient outcomes...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$68K - $103K *

Champion contract negotiation and management, ensuring timely delivery of legal agreements and compliance with project timelines. Collaborate closely with clinical teams across North America and Europ...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$76K - $119K *

Deliver impactful category strategies and sourcing initiatives for technology spend, driving savings and supplier performance while collaborating with cross-functional teams to optimize value and mana...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$204K - $254K *

Engage as a key member of a high-growth team, driving technical solutions and customer success through expert presentations, collaboration, and innovative problem-solving in a dynamic startup environm...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Unlock potential by enhancing our transaction monitoring program. In this hands-on role, you'll design rules, analyze payment activities, and investigate alerts, ensuring compliance and risk managemen...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $130K *

Elevate clinical research by managing trials that showcase AI-enabled care pathways. Lead study execution, ensure compliance, and collaborate across teams to optimize project outcomes while enhancing...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Advance your career by ensuring quality compliance and driving continuous improvement in engineering processes. Collaborate with cross-functional teams to implement effective quality assurance methods...

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$107K - $161K *

Innovate in R&D as a Senior Systems Engineer, bridging early-stage tech and production. Drive feasibility studies, prototype emerging features, and collaborate with partners to advance next-gen archit...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $140K *

Lead operational procurement for network infrastructure and data-center projects. Collaborate with cross-functional teams to source suppliers, negotiate contracts, and ensure compliance with procureme...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $172K *

Transform your career by leading the administration and optimization of key SaaS collaboration and endpoint management platforms, ensuring security and efficiency across the organization while collabo...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$100K - $146K *

Innovate community engagement and operational excellence by overseeing HR processes, vendor management, and local partnerships. Lead the launch of a new office while ensuring compliance and a welcomin...

RemoteRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$75K - $91K *

Unlock potential by managing auto damage claims from inspection to resolution. Collaborate with body shops, negotiate repairs, and ensure customer satisfaction while maintaining compliance with claims...

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $211K *

Lead a dynamic team of Deployment Specialists, overseeing field service operations from deployment to ongoing support, ensuring reliability and customer success with advanced robotic systems in divers...

5 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$135K - $211K *

Optimize field service operations by leading a team of Deployment Specialists, ensuring safe and reliable deployment of robotic systems while enhancing customer satisfaction and operational efficiency...

Pittsburgh, PARemote

5 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Drive incremental sales revenue by prospecting and closing new business. Engage with key decision-makers, manage customer relationships, and leverage channel partners to maximize pipeline success acro...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$88K - $105K *

Elevate quality standards in manufacturing by managing systems and teams to ensure compliance with specifications and production goals. Collaborate with inspectors and lead audits to drive continuous...

5 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $125K *

Join a team that's dedicated to providing comprehensive women's health services. You'll deliver patient-centered care, collaborate in a supportive environment, and make a meaningful impact across dive...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $130K *

Elevate security practices by architecting innovative Python tools for scalable cloud infrastructure. Drive automation and empower teams with self-service solutions while enhancing security across glo...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $171K *

Lead the charge in building and executing a comprehensive commissioning program for Modular Data Centers, ensuring optimal performance from factory testing to operational handover while collaborating...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $140K *

Develop and execute strategic business initiatives, cultivating partnerships and driving revenue growth through market analysis and relationship management. Collaborate with cross-functional teams to...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$193K - $309K *

Lead the charge in delivering impactful GTM solutions by managing a skilled engineering team, overseeing technical operations, and fostering collaboration with stakeholders to drive innovation and qua...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$86K - $176K *

Unlock potential by leveraging data science to drive strategic insights and performance across sales and finance. Collaborate with teams to enhance decision-making through advanced analytics, machine...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Lead the charge in establishing a robust BIM infrastructure, driving digital transformation and AI integration across projects. Oversee standards, mentor teams, and enhance collaboration to elevate de...

5 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$95K - $115K *

Lead the charge in overseeing financial operations, ensuring accuracy and compliance in accounts payable, vendor management, and budgeting. Collaborate with stakeholders to enhance financial processes...

5 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.