Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,521

Sort By: Relevance

$91K - $121K *

Optimize the commercialization process by owning end-to-end management, collaborating across functions, and leveraging AI tools to enhance efficiency and scalability, ultimately driving data integrity...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $140K *

Transform user experiences by building and enhancing robust software solutions across frontend and backend layers, focusing on customer-facing AI products to ensure quality and safety in delivery...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Information Technology

$180K - $220K *

Drive the end-to-end ML and LLM lifecycle, optimizing AI workflows and automations. Collaborate with cross-functional teams to ensure scalable, reliable production of AI-driven solutions while impleme...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Join a team that's redefining growth through innovative design. Collaborate across functions to create impactful user experiences that drive client acquisition and engagement, shaping the future of fi...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$115K - $192K *

Unlock potential as a Pharmacy Value Stream Release Train Engineer, facilitating alignment and execution across teams. Drive continuous improvement and enhance delivery outcomes within a dynamic, Agil...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$132K - $165K *

Join a team that's dedicated to enhancing partner relationships and driving strategic initiatives. Utilize your project management skills to support account growth and ensure partner satisfaction in a...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Advance your career by providing technical leadership in geotechnical engineering. Oversee project quality, mentor emerging leaders, and drive business development while ensuring strategic execution a...

5 days ago

  •   11 - 15 years exp.  •   Business Services

$92K - $130K *

Shape the future of pharmacy benefits by managing key client relationships, ensuring operational excellence, and driving satisfaction through effective communication and problem-solving in a dynamic P...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Champion high-quality software releases by troubleshooting E2E issues, optimizing performance, and leveraging AWS technologies to drive operational efficiency across diverse broadband devices...

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Join a team that's redefining software development by leveraging Java and modern frameworks to create scalable solutions. Collaborate with cross-functional teams to enhance API standards and deliver h...

5 days ago

  •   5 - 7 years exp.  •   Staffing

$95K - $130K *

Join a dynamic team to lead innovative land development projects, driving excellence from design to execution while cultivating client relationships and mentoring junior staff. Elevate your career in...

5 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$200K - $270K *

Shape the future of immunotherapy by leading access strategies for a groundbreaking T-cell therapy. Collaborate with cross-functional teams to ensure timely payer engagement and coverage decisions, ma...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$101K *

Elevate customer engagement by guiding inquiries through quotes and orders. Drive sales growth through proactive outreach and relationship building in a dynamic e-commerce and distribution environment...

5 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$238K - $280K *

Shape the future of AI/LLM security by leading innovative offensive strategies, defining technical vision, and driving cross-company initiatives to enhance NodeZero's capabilities in identifying and e...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$93K - $137K *

Join a dynamic team to enhance partner relationships, drive operational excellence, and foster business growth through strategic onboarding and support initiatives. Leverage your insurance expertise t...

RemoteRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$78K - $100K *

Lead the end-to-end program management for enterprise clients in financial services, driving alignment and execution across cross-functional teams to achieve measurable business outcomes and ensure se...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Media

$84K - $108K *

Drive operational excellence at a major water filtration facility by supervising skilled trades, ensuring maintenance, and fostering a safe work environment. Lead a dedicated team to enhance performan...

5 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$135K - $175K *

Shape the future of engineering projects by leading a talented team. Drive high-quality solutions from concept to completion while managing budgets and schedules. Your expertise will foster collaborat...

5 days ago

  •   8 - 10 years exp.  •   Technical Services

$110K - $130K *

Deliver innovative engineering solutions as a Senior Engineer, leading complex projects, ensuring quality and adherence to schedules and budgets, while mentor junior team members and maintaining stron...

Reposted 5 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$170K - $200K *

Join a team that's dedicated to advancing adolescent health through comprehensive care, research, and education. Collaborate with faculty in a supportive environment focused on quality patient outcome...

5 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$138K - $165K *

Champion the development of LLM-powered applications and agentic systems. Drive complex use cases from ambiguous problems to production, ensuring high-quality and scalable AI solutions that address us...

RemoteRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Information Technology

$236K - $325K *

Lead the charge in global security investigations and incident response, guiding complex incidents while building operational practices and technical capabilities to ensure effective responses across...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $96K *

Transform the lives of elderly residents by providing compassionate care and leadership. Collaborate with a dedicated team to uphold nursing standards and ensure a supportive environment, all while en...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $150K *

Drive underwriting excellence by managing property risks and building strong broker relationships. Collaborate with a dynamic team to deliver innovative solutions in a fully remote environment, focusi...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K *

Drive innovation in healthcare technology by leading product management efforts, connecting cross-functional teams, and shaping the product roadmap to enhance value-based care solutions. Engage hands...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.