Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,521

Sort By: Relevance

$77K - $116K *

Transform data into actionable insights by leading BI application development, collaborating across teams, and ensuring quality reporting solutions that support strategic goals and enhance decision-ma...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$96K - $132K *

Join a team that's dedicated to transforming healthcare through innovative solutions. Collaborate with clients and experts to implement cutting-edge products, ensuring optimal workflows and exceptiona...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$106K - $145K *

Transform the future of healthcare AI by leading quality benchmarks and data analysis for innovative NLP products. Collaborate globally to enhance automated medical note evaluation and deliver actiona...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Lead the development of AI-driven data solutions to optimize business operations. Collaborate with stakeholders to enhance digital transformation initiatives in underwriting and claims functions, driv...

RemoteRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $166K *

Champion integrated workplace strategies that align business goals with real estate solutions. Collaborate across functions to enhance employee experience and operational efficiency while navigating c...

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Shape the future of enterprise infrastructure by designing and supporting critical directory services like Active Directory and DNS, ensuring reliable access across a global landscape while leading pr...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$111K - $185K *

Shape the future of talent strategies in a dynamic organization. Collaborate with leaders to enhance workforce performance, drive organizational change, and support growth initiatives across multiple...

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$223K - $334K *

Lead the charge in establishing investigation excellence and reliability engineering capabilities. Collaborate globally to enhance quality outcomes, drive data-driven decisions, and mentor technical e...

RemoteRemote

5 days ago

  •   11 - 15 years exp.  •   Healthcare

$105K - $158K *

Empower clinical research by overseeing global studies, managing projects, and collaborating with stakeholders to ensure compliance and success from design to implementation. Bring your expertise to d...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K *

Advance clinical expertise in endoscopy solutions by training healthcare providers on innovative technologies, enhancing patient care, and driving product utilization across a multi-state region throu...

Philadelphia, PARemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $165K *

Drive growth by leading consultative sales for women's health benefits. Build relationships, tailor solutions, and close deals while managing a strong sales pipeline and collaborating with internal te...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$96K - $150K *

Lead data analytics initiatives by processing and analyzing aircraft data to enhance C-17 performance. Collaborate with cross-functional teams to troubleshoot issues and develop algorithms for efficie...

5 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$148K - $215K *

Unlock potential by leading the design and optimization of enterprise load balancing solutions. Collaborate with cross-functional teams to enhance application delivery, ensuring high availability and...

5 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$126K - $171K *

Elevate your career by leading integrated planning and scheduling efforts, ensuring alignment across teams and driving best practices in project management for complex development programs...

5 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$157K - $227K *

Champion the transformation of ERP processes by leading employee engagement and training initiatives, ensuring effective adoption of SAP S4/HANA across functional teams while enhancing operational rea...

5 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$75K - $144K *

Transform supply chain operations by serving as a key contact for IT COTS products, enhancing customer service, and driving improvements through technical expertise and collaboration in a dynamic envi...

5 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$57K - $108K *

Join a dynamic team to support aircraft systems integration and testing. Collaborate with global engineers on mechanical, electro-mechanical, and electronic systems for Safety, Cargo, and Lighting, en...

5 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$145K - $276K *

Drive production and sustainment efforts for critical defense contracts, ensuring strategic execution and collaboration across teams. Engage with stakeholders to enhance product integrity and deliver...

5 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$68K - $131K *

Join a dynamic team as you support program management through financial reporting, analysis, and collaboration. This role offers opportunities for growth while ensuring efficiency and quality in progr...

5 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$107K - $204K *

Reimagine systems engineering by leveraging your expertise in requirements development, architecture, and integration. Collaborate with teams to enhance system design and verification processes, ensur...

5 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$107K - $204K *

Drive innovative sourcing strategies for new product development, collaborating with cross-functional teams to ensure supply chain readiness, cost efficiency, and quality standards are met throughout...

5 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$80K - $95K *

Join us to manage and enhance our consumer purchase data assets, collaborating with vendors and internal teams to ensure high-quality data acquisition and compliance, driving insights and analytics fo...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$144K - $288K *

Lead the charge in developing cutting-edge digital applications leveraging AI, optimizing performance across major cloud platforms while driving excellence in software engineering practices and collab...

RemoteRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$124K - $158K *

Advance your career by delivering excellent patient care, managing pharmacy operations, and supporting your team. Be a trusted partner in improving health outcomes while fostering a culture of safety...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$146K - $169K *

Join a leading healthcare provider to deliver high-quality, patient-centered care in a collaborative clinic environment. Empower patients through both in-person and virtual visits, ensuring comprehens...

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.