Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,442

Sort By: Relevance

$170K - $184K *

Champion the delivery and strategic growth of government programs, leading cross-functional teams to drive excellence and innovation. Collaborate with stakeholders to enhance service quality and finan...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Develop and oversee power plant thermal performance analysis, modeling, and testing. Collaborate with teams to ensure accurate data collection and reporting, while supporting project design efforts an...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$145K - $215K *

Lead the charge in shaping a robust talent acquisition strategy to drive growth. Oversee full-cycle recruiting for commercial roles, collaborating with executives to build high-performing teams across...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Unlock potential by leading client relationships and driving strategic measurement initiatives. Manage a diverse portfolio, ensuring retention and growth while guiding teams to deliver impactful marke...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Enterprise Technology

$116K - $124K *

Unlock potential by providing essential medical care and support to donors, ensuring safety and satisfaction while adhering to regulatory standards. Collaborate with a dedicated team to enhance donor...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $150K *

Drive growth by building strategic partnerships and closing new business opportunities. Utilize a consultative approach to address client needs with innovative out-of-home solutions, while managing yo...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Media

$95K - $115K *

Lead financial and regulatory reporting engagements, manage teams, and ensure compliance with US GAAP and IFRS. Foster client relationships and enhance service offerings while guiding staff in a dynam...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Tackle critical cybersecurity challenges as an Information Assurance Analyst, ensuring compliance and security for key Army systems. Collaborate with technical teams to conduct vulnerability assessmen...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Partner with us to drive data-informed marketing strategies and optimize measurement practices. Leverage your analytics skills to guide clients, enhance performance, and manage a talented team while f...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$75K - $125K *

Shape the future of strategic initiatives by analyzing business needs, managing stakeholder partnerships, and delivering impactful solutions that drive transformation and enhance operational efficienc...

Reposted today

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $155K *

Shape the future of enterprise networking by leading integration strategies for mergers and acquisitions. Drive technical assessments, develop migration roadmaps, and collaborate across teams to ensur...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Engage with clients to develop tailored investment and insurance strategies. Drive relationship growth, provide exceptional service, and collaborate with internal partners to enhance client experience...

Reposted today

  •   Less than 5 years exp.  •   Finance & Insurance

$106K - $264K *

Lead growth by generating new business and driving revenue through extensive relationship building and sales strategies. Engage with C-level executives in a dynamic, remote environment to exceed quart...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$150K - $197K *

Lead the charge in optimizing operations within a federal acquisition service, providing strategic direction and oversight for service centers. Drive efficiency, cultivate partnerships, and ensure ali...

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Transform infrastructure projects by leading Civil BIM initiatives, optimizing workflows, and advancing digital delivery practices. Collaborate with teams to enhance modeling standards and integrate e...

Today

  •   5 - 7 years exp.  •   Technical Services

$145K - $150K *

Drive sales success as a Territory Sales Manager, expanding customer relationships and achieving targets across Pennsylvania, New Jersey, and Delaware. Collaborate with teams to enhance business growt...

Today

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Engage in strategic leadership for clinical documentation integrity and post-discharge review. Drive initiatives that enhance quality outcomes, compliance, and reimbursement accuracy while fostering c...

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$250K - $300K *

Join a dynamic team of Gastroenterologists focused on delivering exceptional patient care, diagnosing GI disorders, and performing advanced endoscopic procedures in a collaborative healthcare environm...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$85K - $102K *

Join a team that's dedicated to enhancing internal audit processes. Leverage your expertise in auditing standards and healthcare to drive compliance and efficiency while collaborating across all organ...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead a dynamic payroll services team, overseeing multi-client payroll processing, ensuring compliance, and advising clients across diverse industries while fostering team development and process impro...

Today

  •   8 - 10 years exp.  •   Legal & Accounting

$121K - $174K *

Shape the future of client relationships by leading strategic initiatives, mentoring teams, and driving innovative marketing solutions. Collaborate with senior leadership to deliver impactful results...

Today

  •   8 - 10 years exp.  •   Media

$145K - $181K *

Transform complex thermal simulations to optimize designs and manufacturing processes. Collaborate with cross-functional teams to enhance product performance and validate concepts through advanced ana...

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Champion customer success by building strong relationships, ensuring seamless contract processing, and delivering top-notch service. Collaborate with diverse stakeholders to resolve issues and enhance...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$180K - $220K *

Lead the development and execution of a commercial growth strategy, focusing on market discovery, customer acquisition, and scalable offerings to drive robotics and AI adoption in manufacturing sector...

Today

  •   15+ years exp.  •   Manufacturing & Automotive

$120K - $145K *

Deliver innovative solutions as a Senior C++ Engineer, driving development in the gaming industry. Collaborate in a dynamic, remote environment, leveraging your expertise in C++ and Windows systems to...

Reposted today

  •   8 - 10 years exp.  •   Staffing

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.