Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,521

Sort By: Relevance

$170K - $200K *

Champion operational excellence by leading business unit strategies, enhancing performance management, and driving cross-functional collaboration to achieve enterprise goals and scalable solutions...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Unlock potential by leading quality assurance initiatives in a dynamic pharmaceutical environment. Drive compliance, manage audits, and enhance supplier qualifications to ensure operational excellence...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Champion customer success by leading enterprise deployments and integrations. Drive technical direction and enhance automation for cloud services, ensuring seamless operations and improved customer ex...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$71K - $125K *

Transform client relationships by supporting sales and credit functions, managing lending processes under $10M, and ensuring data integrity. Collaborate with teams to create impactful pitch materials...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $110K *

Champion data integrity and reporting readiness by managing data ingestion, ensuring quality, and collaborating across teams to support healthcare marketing analytics and decision-making processes...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion operational excellence by leading strategic initiatives that enhance guest satisfaction, drive revenue growth, and foster employee development while ensuring alignment with brand standards an...

3 days ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$102K - $184K *

Unlock potential by leading high-impact engagements in digital assets, guiding clients through evolving risks and regulatory landscapes while enhancing internal controls and operational strategies in...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$111K - $183K *

Empower your career by leading enterprise architecture initiatives, guiding technology direction, and driving modernization efforts across systems, cloud, and O365. Collaborate with cross-functional t...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$170K - $200K *

Lead the charge in shaping our AI strategy and governance, driving innovation across teams. Collaborate with technology and business leaders to embed AI into operations, ensuring responsible use and m...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$99K - $164K *

Drive impactful data-driven projects by leading a diverse team in fraud detection and prevention. Manage contract delivery, timelines, and client relationships while ensuring effective communication a...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$107K - $204K *

Join a dynamic team to oversee end-to-end delivery of digital products, leading requirements, functional design, and testing. Collaborate with cross-functional teams to drive quality initiatives and e...

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$250K - $500K *

Champion innovative wound care solutions while collaborating with skilled nursing facilities. Utilize your clinical expertise to evaluate and treat complex wounds, ensuring optimal patient outcomes in...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $300K *

Inspire excellence in patient care by joining a dynamic team of dermatology professionals. Collaborate with top experts and leverage advanced technologies to provide exceptional medical and cosmetic s...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$132K - $271K *

Transform software sales by originating and advancing opportunities within assigned territories. Collaborate with client teams, manage pipelines, and support partners while guiding junior members to a...

3 days ago

  •   8 - 10 years exp.  •   Business Services

$132K - $271K *

Champion the future of software sales by driving pipeline growth and executing deals. Collaborate with clients and partners to deliver tailored solutions, while mentoring junior team members and navig...

3 days ago

  •   8 - 10 years exp.  •   Business Services

$132K - $271K *

Join a team that's redefining pre-sales excellence by delivering tailored software solutions, engaging clients through compelling demos, and driving strategic partnerships to enhance business outcomes...

3 days ago

  •   8 - 10 years exp.  •   Business Services

$132K - $271K *

Champion your career by driving pre-sales excellence in complex software solutions. Leverage your expertise to deliver impactful demos, engage clients, and develop strategic assets that enhance sales...

3 days ago

  •   8 - 10 years exp.  •   Business Services

$146K - $243K *

Drive impactful sales strategies in the Bone Marrow Transplant space, fostering relationships with healthcare providers and key opinion leaders to enhance patient outcomes and achieve territory goals...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $149K *

Lead complex K-12 capital projects as an owner's representative, managing MEP systems from planning to closeout. Drive project success through effective stakeholder coordination, risk management, and...

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Optimize enterprise solutions by developing and integrating AI-powered agents using Microsoft Power Platform. Ensure secure, maintainable, and production-ready applications that enhance business proce...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $149K *

Seeking an experienced MEP Manager to oversee K-12 capital projects, ensuring successful delivery through all phases. Collaborate with multidisciplinary teams to manage scope, budget, and quality whil...

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$90K - $115K *

Join a dynamic team to enhance cybersecurity for critical DOD systems. Support compliance, risk management, and technical documentation efforts while collaborating with engineers and program managers...

3 days ago

  •   Less than 5 years exp.  •   Technical Services

$140K - $165K *

Empower your career by proactively identifying and mitigating insider threats. This role involves advanced investigations, threat detection, and collaboration to protect critical data and intellectual...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Staffing

$73K - $110K *

Analyze coding quality data and support compliance initiatives to enhance hospital coding accuracy. Collaborate with teams to develop guidance and conduct audits, ensuring adherence to regulatory stan...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $170K *

Lead strategic contracts management, overseeing development and negotiation of federal contracts. Collaborate cross-functionally to ensure compliance and risk management while driving organizational g...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.