Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.
Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.
Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.
Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.
Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.
Average Salary: $122,521
Deals Delivering Deal Value HR Due Diligence Senior Associate
$77K - $202K *
Shape impactful HR due diligence for transactions, analyzing workforce implications and guiding clients through mergers and acquisitions. Mentor junior team members while delivering actionable insight...
3 days ago
Clinical Theranostic Specialist
$134K - $162K *
Lead the charge in advancing clinical adoption and workflow optimization for radiopharmaceutical products. Collaborate cross-functionally to ensure safe, compliant practices while building strategic r...
3 days ago
Senior Director, Business Management & Execution Lead
$170K - $200K *
Champion operational excellence by leading business unit strategies, enhancing performance management, and driving cross-functional collaboration to achieve enterprise goals and scalable solutions...
3 days ago
Sr. Quality Specialist, QMS & Compliance
$95K - $115K *
Unlock potential by leading quality assurance initiatives in a dynamic pharmaceutical environment. Drive compliance, manage audits, and enhance supplier qualifications to ensure operational excellence...
3 days ago
Senior/Staff Platform Engineer, Enterprise Deployments
$135K - $160K *
Champion customer success by leading enterprise deployments and integrations. Drive technical direction and enhance automation for cloud services, ensuring seamless operations and improved customer ex...
3 days ago
$71K - $125K *
Transform client relationships by supporting sales and credit functions, managing lending processes under $10M, and ensuring data integrity. Collaborate with teams to create impactful pitch materials...
3 days ago
Business Intelligence Solution Developer
$90K - $110K *
Champion data integrity and reporting readiness by managing data ingestion, ensuring quality, and collaborating across teams to support healthcare marketing analytics and decision-making processes...
3 days ago
General Manager, The Ritz-Carlton St. Thomas
$110K - $130K *
Champion operational excellence by leading strategic initiatives that enhance guest satisfaction, drive revenue growth, and foster employee development while ensuring alignment with brand standards an...
3 days ago
Risk Advisory Manager (Digital Assets)
$102K - $184K *
Unlock potential by leading high-impact engagements in digital assets, guiding clients through evolving risks and regulatory landscapes while enhancing internal controls and operational strategies in...
3 days ago
Enterprise and Solutions Architect III
$111K - $183K *
Empower your career by leading enterprise architecture initiatives, guiding technology direction, and driving modernization efforts across systems, cloud, and O365. Collaborate with cross-functional t...
3 days ago
Sr. Director, AI Strategy & Enablement
$170K - $200K *
Lead the charge in shaping our AI strategy and governance, driving innovation across teams. Collaborate with technology and business leaders to embed AI into operations, ensuring responsible use and m...
3 days ago
$99K - $164K *
Drive impactful data-driven projects by leading a diverse team in fraud detection and prevention. Manage contract delivery, timelines, and client relationships while ensuring effective communication a...
Reposted 3 days ago
Quality System Manager (Onsite)
$107K - $204K *
Join a dynamic team to oversee end-to-end delivery of digital products, leading requirements, functional design, and testing. Collaborate with cross-functional teams to drive quality initiatives and e...
3 days ago
$250K - $500K *
Champion innovative wound care solutions while collaborating with skilled nursing facilities. Utilize your clinical expertise to evaluate and treat complex wounds, ensuring optimal patient outcomes in...
3 days ago
Dermatologist - King of Prussia, PA
$250K - $300K *
Inspire excellence in patient care by joining a dynamic team of dermatology professionals. Collaborate with top experts and leverage advanced technologies to provide exceptional medical and cosmetic s...
3 days ago
Software Sales Senior Manager - Manufacturing Software
$132K - $271K *
Transform software sales by originating and advancing opportunities within assigned territories. Collaborate with client teams, manage pipelines, and support partners while guiding junior members to a...
3 days ago
Software Sales Senior Manager - Manufacturing Software
$132K - $271K *
Champion the future of software sales by driving pipeline growth and executing deals. Collaborate with clients and partners to deliver tailored solutions, while mentoring junior team members and navig...
3 days ago
Software Product Management Pre Sales Senior Manager - Marketing Analytics Software
$132K - $271K *
Join a team that's redefining pre-sales excellence by delivering tailored software solutions, engaging clients through compelling demos, and driving strategic partnerships to enhance business outcomes...
3 days ago
Software Product Management Pre Sales Senior Manager - Marketing Analytics Software
$132K - $271K *
Champion your career by driving pre-sales excellence in complex software solutions. Leverage your expertise to deliver impactful demos, engage clients, and develop strategic assets that enhance sales...
3 days ago
Therapeutic Area Lead, Bone Marrow Transplant, New York
$146K - $243K *
Drive impactful sales strategies in the Bone Marrow Transplant space, fostering relationships with healthcare providers and key opinion leaders to enhance patient outcomes and achieve territory goals...
3 days ago
$130K - $149K *
Lead complex K-12 capital projects as an owner's representative, managing MEP systems from planning to closeout. Drive project success through effective stakeholder coordination, risk management, and...
3 days ago
Senior Power Platform Developer/AI Automation Engineer
$110K - $130K *
Optimize enterprise solutions by developing and integrating AI-powered agents using Microsoft Power Platform. Ensure secure, maintainable, and production-ready applications that enhance business proce...
3 days ago
$130K - $149K *
Seeking an experienced MEP Manager to oversee K-12 capital projects, ensuring successful delivery through all phases. Collaborate with multidisciplinary teams to manage scope, budget, and quality whil...
3 days ago
Information Systems Security Engineer I
$90K - $115K *
Join a dynamic team to enhance cybersecurity for critical DOD systems. Support compliance, risk management, and technical documentation efforts while collaborating with engineers and program managers...
3 days ago
Threat Hunter Investigator - 177302 - 177697
$140K - $165K *
Empower your career by proactively identifying and mitigating insider threats. This role involves advanced investigations, threat detection, and collaboration to protect critical data and intellectual...
3 days ago
What kinds of high-paying jobs can I find in Pennsylvania?
Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.
Do Pennsylvania jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.
How can I narrow my search for jobs in Pennsylvania?
Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.
Are remote or hybrid jobs available in Pennsylvania?
Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.