Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,521

Sort By: Relevance

$83K - $117K *

Empower business growth by leading experimentation strategies and analytical initiatives. Utilize advanced statistical techniques to analyze complex datasets, influence decision-making, and drive impa...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $110K *

Join a team that's dedicated to enhancing software quality through innovative testing strategies. Collaborate with cross-functional teams to ensure reliable applications that support clinical research...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in nursing excellence by driving quality, safety, and growth initiatives. Collaborate with interdisciplinary teams to enhance patient care and operational effectiveness while fostering...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to sourcing top technical talent for innovative automation solutions. Leverage your recruiting expertise to engage candidates and support our mission of enhancing efficien...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Accelerate progress at enterprise-level accounts by driving new-logo acquisition and managing a strategic territory plan. Engage C-suite stakeholders and lead complex sales cycles to achieve significa...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$211K - $264K *

Transform learning experiences by leading the strategy and operations of our enterprise learning technology ecosystem, ensuring effective governance and seamless integration across platforms to enhanc...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$145K - $220K *

Drive the marketing strategy and pipeline generation for a high-growth B2B company. Lead a dynamic team to create demand, optimize engagement, and deliver measurable results while fostering a culture...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$179K - $293K *

Drive regulatory strategies for In Vitro Diagnostics and Digital Health, overseeing development, submissions, and commercialization. Collaborate with stakeholders and lead health authority meetings to...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $210K *

Drive success by leading a high-impact Cyber Security Sales team, achieving sales targets, and fostering strategic partnerships. Collaborate across functions to align technical and business strategies...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Transform the future of intelligent compiler technologies by designing and optimizing advanced systems that enhance developer productivity and system performance across software and hardware boundarie...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$140K - $167K *

Champion growth by driving Chainguard's SEO and developer marketing strategies. Collaborate cross-functionally to enhance visibility and user adoption, focusing on measurable outcomes and pipeline gro...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$108K - $251K *

Empower customer success by leading the design and implementation of AI and CCaaS solutions. Collaborate with cross-functional teams to create scalable architectures that enhance customer experience a...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Consumer Technology

$110K - $130K *

Drive global hazard communication strategies to ensure compliance and support business growth. Lead a team in developing Safety Data Sheets and product labeling while optimizing processes for efficien...

3 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$265K - $290K *

Unlock growth by shaping our partner go-to-market strategy in the Western region. Collaborate with cross-functional teams to drive revenue through strategic partnerships, enhancing our channel ecosyst...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Lead the charge in securing enterprise applications by conducting thorough penetration tests, validating vulnerabilities, and collaborating with engineering teams to enhance security measures across d...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$124K - $280K *

Transform client operations by leading SAP application development and integration projects. As a Senior Manager, guide teams through complex challenges, ensuring alignment with business objectives wh...

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$124K - $280K *

Lead the charge in SAP application development and integration, guiding teams through complex projects while advising clients on finance technology solutions. Shape strategies that enhance operational...

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$110K - $130K *

Champion a high-performing sales team by driving revenue growth, coaching talent, and executing strategic initiatives. Leverage data insights to enhance performance and foster a culture of accountabil...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$85K - $90K *

Drive precision in CNC operations by setting up and managing equipment, ensuring quality and efficiency while mentoring junior operators and collaborating with teams to meet production goals...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$124K - $158K *

Join us to enhance patient care as a Staff Pharmacist, overseeing pharmacy operations, ensuring compliance, and leading a dedicated team. Your expertise will drive safe dispensing, patient counseling...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Unlock potential by leading Oracle Financials implementations, driving discovery, architecture, and hands-on configuration across multiple engagements. Collaborate with finance teams to deliver tailor...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$80K - $95K *

Empower the next generation of legal professionals by mentoring students, teaching clinical courses, and engaging in curriculum development within a collaborative academic environment focused on high...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$90K *

Lead the charge in delivering exceptional clinical support and training for patient monitoring systems. Collaborate with teams to ensure timely implementation and ongoing customer satisfaction across...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $200K *

Redefine healthcare leadership by managing operations across multiple hospitals, ensuring policy implementation, and fostering collaboration among stakeholders to achieve operational excellence and co...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Unlock your potential as an Oracle Data Migration Architect, leading complex data conversions from legacy systems to Oracle Fusion Cloud. Collaborate with cross-functional teams to ensure seamless exe...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.