Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,442

Sort By: Relevance

$85K - $100K *

Transform healthcare by driving sales of trauma products, engaging with surgeons and healthcare professionals. Leverage expertise to provide solutions in high-pressure environments, ensuring optimal p...

Today

  •   Less than 5 years exp.  •   Healthcare

$108K - $155K *

Empower patient care by joining a dedicated team that provides telephonic support, addresses diverse medical and psychological needs, and enhances patient experiences while ensuring documentation accu...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Shape the future of healthcare staffing by building strong client relationships, driving sales, and collaborating with a dedicated team to meet client needs and exceed targets in a dynamic environment...

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$150K - $190K *

Drive innovation by architecting scalable AI solutions that transform business processes across multiple domains. Collaborate with leaders to establish enterprise standards and governance frameworks f...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$69K - $104K *

Unlock your potential by collaborating with leaders to enhance payor performance, streamline revenue cycle operations, and drive innovation in healthcare. Your expertise will ensure impactful engageme...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $231K *

Transform healthcare outcomes by leading a team of Clinical Program Consultants to analyze data, optimize clinical programs, and drive strategic initiatives that enhance customer health and reduce cos...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Grow your career with a dynamic role in data science, where you'll analyze data, develop machine learning models, and create impactful visualizations to drive business insights and support decision-ma...

Today

  •   Less than 5 years exp.  •   Business Services

$99K - $232K *

Join a team that empowers clients to enhance operational performance through strategic analysis, lean manufacturing, and digital transformation methodologies in manufacturing excellence, driving susta...

Reposted today

  •   5 - 7 years exp.  •   Legal & Accounting

$99K - $232K *

Unlock potential by optimizing operational efficiency and driving lean manufacturing principles. Collaborate with clients to enhance product development lifecycles, improve quality, reduce costs, and...

Reposted today

  •   5 - 7 years exp.  •   Legal & Accounting

$125K - $150K *

Drive technical solutions as a client-facing architect, leveraging deep expertise in JavaScript, TypeScript, and Python to guide enterprise-level projects across multiple cloud environments and enhanc...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$90K - $143K *

Advance your career by supporting client data integration and automation. Collaborate with cross-functional teams to ensure reliable data movement and timely issue resolution, enhancing service delive...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $134K *

Optimize work scheduling and maintenance activities to enhance operational efficiency. Collaborate with cross-functional teams and manage work scopes to ensure timely project execution while minimizin...

Reposted today

  •   5 - 7 years exp.  •   Energy & Utilities

$95K - $143K *

Empower pricing strategies by bridging business needs with AI solutions. Collaborate with teams to prototype, validate, and scale AI-driven pricing automation, enhancing decision-making and operationa...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Explore a pivotal role in our Security Operations Center, leading investigations, mentoring junior analysts, and enhancing incident response strategies. Collaborate with teams to refine detection meth...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Join us to lead the strategy and development of private label fresh products, driving innovation across grocery and foodservice channels while collaborating with cross-functional teams to deliver winn...

Today

  •   5 - 7 years exp.  •   Food & Beverages

$85K *

Optimize preventive maintenance operations by supervising personnel and coordinating maintenance activities for power generation equipment, ensuring reliability and safety in a 24/7 service environmen...

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$100K *

Elevate your career by driving sales and building relationships in a dynamic insurance environment. Leverage your expertise to generate leads, close deals, and support clients while enjoying a flexibl...

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Unlock your potential by leading project procurement efforts, optimizing processes, and managing supplier relationships to enhance operational efficiency and profitability across diverse project categ...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Energy & Utilities

$120K - $160K *

Join a team that's redefining integrated marketing strategies, leading cross-channel campaigns that drive product narratives and customer engagement. Shape the future of marketing through collaboratio...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Lead the charge in materials and failure analysis, driving root-cause investigations and cross-functional collaboration to enhance battery performance, safety, and reliability. Utilize engineering exp...

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$80K - $95K *

Engage with clients to drive sales of advanced intralogistics solutions. Utilize your expertise to develop accounts within manufacturing and e-commerce sectors while exceeding customer expectations an...

Reposted today

  •   5 - 7 years exp.  •   Real Estate & Construction

$124K - $224K *

Unlock potential by leading revenue operations, bridging sales, finance, and analytics. Drive forecasting, pipeline management, and team development to enhance business performance and ensure data int...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Energy & Utilities

$75K - $90K *

Elevate your career by generating new loan opportunities, building strong relationships, and managing a dynamic loan pipeline. Drive success through strategic outreach and exceptional customer service...

Scranton, PARemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$151K - $248K *

Unlock your potential by driving product innovation and cross-functional alignment in a dynamic environment. Lead initiatives that shape lending solutions, enhance decision-making, and deliver impactf...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Join a dynamic engineering team to transform concepts into functional system components, ensuring integration and performance meet requirements while collaborating across disciplines to shape future p...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.