Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,477

Sort By: Relevance

$150K - $180K *

Grow enterprise SAP relationships by managing key accounts and driving new business. Leverage your expertise to expand client portfolios, develop strategic plans, and ensure client satisfaction while...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$92K - $109K *

Join a team that's driving enterprise-level marketing strategies across diverse client segments. As a key player, you'll lead high-visibility initiatives, collaborate with cross-functional teams, and...

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$163K - $224K *

Drive strategic planning and execution of acquisitions/divestitures, ensuring seamless integration and value creation across teams. Collaborate cross-functionally to manage milestones, risks, and comm...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$92K - $109K *

Unlock potential by leading national marketing initiatives and thought leadership programs. Collaborate with cross-functional teams to drive enterprise strategies and elevate brand presence through in...

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$118K - $196K *

Tackle the complexities of employee equity programs by leading stock plan operations, ensuring compliance, and collaborating with cross-functional teams to enhance financial controls and reporting for...

Today

  •   5 - 7 years exp.  •   Healthcare

$144K - $240K *

Transform healthcare delivery by leading strategic initiatives and optimizing infusion services. Drive client success through expert guidance, operational excellence, and innovative solutions, ensurin...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Take ownership of the Colleague Accounts Receivable solutions, collaborating with higher education clients to design, implement, and optimize systems while ensuring effective billing, payment processi...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Transform AI infrastructure by designing and maintaining production-grade systems across multiple cloud providers. Engage in hands-on architecture decisions, ensuring reliability, security, and automa...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Unlock potential by leading pre-sales technical strategies that align solutions with client needs, driving revenue growth and retention through collaboration with sales teams and delivering tailored p...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$63K - $108K *

Lead enterprise accounts with 75+ locations, driving SaaS adoption and maximizing business value. Utilize industry expertise to resolve challenges, enhance client relationships, and support strategic...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $110K *

Champion the operational excellence of Workday by overseeing daily support, configuration, and continuous improvement initiatives. Collaborate cross-functionally to resolve issues and enhance function...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $140K *

Champion product storytelling and market positioning to drive success for B2B SaaS solutions. Collaborate across teams to execute impactful launches and empower sales, ensuring alignment with customer...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$82K *

Contribute to our team by driving local routes, ensuring timely deliveries while enjoying a supportive work environment and modern fleet. Experience the benefits of returning home daily with competiti...

Today

  •   Less than 5 years exp.  •   Transportation

$80K - $95K *

Transform clinical operations by leading staff and managing resources to ensure quality patient care in general surgery and procedural settings. Collaborate with interdisciplinary teams to enhance pat...

Today

  •   Less than 5 years exp.  •   Healthcare

$189K - $235K *

Lead the marketing investment strategy, optimizing budget allocation between brand and performance. Collaborate with finance and executive teams to ensure effective spending and measurable returns, dr...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$95K - $115K *

Transform control systems in the field as you analyze PLC code, troubleshoot equipment, and ensure regulatory compliance. Collaborate with internal teams and clients while traveling extensively across...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$76K - $138K *

Empower your career by joining a dynamic team where you'll tackle complex technology projects, enhance your skills, and collaborate across functions to deliver innovative solutions in areas like softw...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$107K - $204K *

Lead the charge in ensuring test facilities are primed for military and commercial engine testing. Collaborate with diverse teams to enhance operations, troubleshoot issues, and advocate for safety in...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$128K - $192K *

The Workday Financials Integrations Senior Principal Consultant - Global AMS is a seasoned professional responsible for leading integration efforts and managing Workday financial services for clients...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Advance fleet business development by building relationships, driving sales, and implementing strategic initiatives to capture market share in the automotive fleet sector. Collaborate with teams to en...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Transform customer relationships by leveraging expertise in automotive technology and solutions. Drive product adoption, retention, and growth across dealer accounts to achieve measurable outcomes and...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Consumer Technology

$150K - $180K *

Lead clinical operations for Immunology, driving strategy and execution of complex studies. Manage teams, oversee budgets, and ensure compliance while fostering a collaborative culture focused on qual...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $140K *

Transform campus public safety through innovative drone solutions, managing full-cycle sales in a competitive market. Build relationships, drive consensus, and leverage AI tools to enhance safety prog...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Consumer Technology

$78K - $85K *

Lead the charge in executing influencer marketing projects from inception to completion, ensuring exceptional client service and strategic solutions while managing timelines, budgets, and cross-functi...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Media

$132K - $193K *

Lead the charge in portfolio strategy and governance, aligning enterprise initiatives with corporate priorities. Drive investment decisions and enhance execution across Product Infrastructure, ensurin...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Telecommunications & Hardware

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.