Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,521

Sort By: Relevance

$95K - $115K *

Champion the integration of acquired companies by managing cross-functional activities, timelines, and risks. Collaborate with leadership to ensure smooth transitions while maintaining operational con...

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$118K - $147K *

Unlock potential by leading cross-functional teams in mission-critical projects. Oversee deliverables, manage client relationships, and drive strategic business development while ensuring project obje...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$139K - $174K *

Join a team that's shaping the future of mission-critical projects. Lead cross-functional teams, oversee deliverables, and enhance client relationships while managing complex, large-scale projects in...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Optimize your skills as a .NET Developer, focusing on software development, testing, and maintenance. Collaborate with a team to deliver high-quality applications while keeping up with industry standa...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Drive partner success by managing a portfolio of consulting and technology partners, building joint pipelines, and enabling co-selling strategies to achieve revenue goals in a dynamic B2B SaaS environ...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Lead the development of innovative software solutions by mastering .NET technologies, collaborating with cross-functional teams, and delivering high-quality applications that transform client needs in...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$104K - $126K *

Lead the charge in managing a dynamic Financial Crimes Intelligence team, overseeing investigations, enhancing monitoring systems, and developing strategies to mitigate financial crime risks while ens...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate your career by developing innovative Salesforce solutions that enhance customer support and experience. Collaborate with cross-functional teams to design, implement, and optimize integrations...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Champion reliability analysis to support New Services Requests in the PJM Interconnection Process. Collaborate with teams to evaluate transmission reinforcements and provide recommendations while mana...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$107K - $147K *

Unlock potential by joining a dynamic team to build scalable applications, tackle distributed systems challenges, and leverage AI for smarter development. Collaborate closely with product management a...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$114K - $167K *

Lead the charge in optimizing ERP systems through advanced customizations, integration solutions, and data migration strategies. Collaborate with teams to enhance performance, ensure compliance, and d...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$75K - $104K *

Champion community health by assessing needs, developing initiatives, and providing education. Engage with partners to enhance public health actions and support case management, ensuring a healthier c...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$94K - $152K *

Lead cross-functional projects as a DMS IT Business Analyst, collaborating with stakeholders to gather requirements, optimize dealer systems, and implement technology solutions that enhance overall us...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$106K - $167K *

Champion complex ERP transformations by analyzing business processes, defining solution architecture, and leading data migrations to optimize finance operations and ensure compliance with industry sta...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $96K *

Engage clients in the aviation sector by driving software sales and solutions. Utilize your industry expertise to build relationships and exceed sales goals while collaborating with teams to enhance s...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Oversee aseptic manufacturing processes, ensuring compliance with cGMP standards while developing staff and enhancing operational efficiency. Lead a team in a dynamic environment, focusing on quality...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$196K - $240K *

Join a team that's driving drug substance technology transfer and operational excellence across CDMO sites. Lead manufacturing oversight, ensure compliance, and foster cross-functional partnerships to...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$241K - $295K *

Drive drug substance commercial manufacturing excellence by leading technology transfer, operational oversight, and continuous improvement initiatives across multiple CDMO sites, ensuring alignment wi...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Empower growth by owning strategic partnerships, driving go-to-market plans, and ensuring compliance. Collaborate across teams to enhance revenue and strengthen relationships, while managing budgets a...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Drive operational excellence by leading revenue operations strategy, optimizing processes, and enhancing cross-functional alignment to support scalable growth and measurable outcomes in a dynamic envi...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$85K - $105K *

Engineer innovative mechanical solutions for overhead cranes and industrial lifting systems. Lead projects from design to execution, ensuring safety, compliance, and customer satisfaction while managi...

2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$77K - $104K *

Engage with federal stakeholders to advance the University’s mission through strategic advocacy, policy analysis, and collaboration. Support key initiatives and facilitate impactful events that align...

2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Drive investment research and portfolio management by conducting due diligence, developing strategies, and presenting insights to enhance multi-asset portfolios and client solutions. Collaborate with...

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$140K - $167K *

Join a team that's redefining growth operations by architecting systems and workflows that drive our go-to-market engine. Lead initiatives, collaborate across functions, and innovate with data to enha...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a team that's driving revenue recognition and cash conversion processes. As a key contributor, you'll optimize practices, enhance systems, and ensure compliance with ASC 606 while collaborating w...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.