Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,442

Sort By: Relevance

$128K - $205K *

Join us to transform the retail landscape by building relationships with convenience stores and grocery outlets. Utilize your sales expertise to drive our innovative solutions, ensuring success for ne...

Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $200K *

Lead the charge in optimizing clinical documentation processes, enhancing provider education, and fostering collaboration with service line leaders to improve documentation integrity and reduce admini...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$157K - $196K *

Drive safety evaluation and risk management for assigned programs, collaborating with cross-functional teams to ensure compliance and effective governance in pharmacovigilance activities, while suppor...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$86K - $124K *

Lead the charge in transforming lives as a Board-Certified Behavior Analyst, providing tailored ABA services to children and adolescents. Collaborate with a multidisciplinary team to foster growth and...

Today

  •   Less than 5 years exp.  •   Healthcare

$125K - $165K *

Empower public housing clients by leading Yardi software implementations, optimizing workflows, and enhancing operational efficiency. Collaborate with stakeholders to resolve issues and drive value in...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$125K - $165K *

Deliver exceptional Yardi software solutions for public housing clients, optimizing implementations and configurations. Collaborate with stakeholders to enhance workflows, troubleshoot issues, and ens...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$110K - $130K *

Lead the charge in building a robust outsourced finance practice, delivering exceptional client service while mentoring team members. Manage client relationships, develop new business, and ensure fina...

Today

  •   8 - 10 years exp.  •   Legal & Accounting

$80K - $95K *

Contribute to dental practice success by delivering impactful, in-person training on digital workflows and intraoral scanning. Collaborate with clinicians and staff to enhance clinical performance and...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$156K - $247K *

Lead the charge in defining media strategies and optimizing promotional efforts for Oncology assets. Collaborate with cross-functional teams to maximize business impact through data-driven insights an...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $225K *

Join a team that's driving innovation in AI by developing scalable backend systems in Go, Python, and Java. Tackle complex challenges while enhancing distributed architectures to empower high-performa...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$120K - $151K *

Shape the product roadmap and drive delivery from discovery to launch, collaborating with cross-functional teams to ensure customer-centric solutions and measurable business outcomes in a dynamic B2B...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $145K *

Join a team that's leading the deployment of Manufacturing Execution Systems (MES) for biologics facilities. Collaborate across engineering, manufacturing, and quality teams to enhance production effi...

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$83K - $93K *

Transform the nursing experience by leading a dedicated team in providing exceptional care, ensuring safety and dignity for residents while managing personnel and fostering a collaborative environment...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$71K - $113K *

Contribute to project success by managing cost and schedule for plant outages. Collaborate with project teams to analyze budgets, track progress, and ensure timely reporting, all while adhering to pro...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Energy & Utilities

$85K - $135K *

Collaborate to drive technical issue resolution and enhance support systems while serving enterprise clients across our AI platform, ensuring seamless communication and operational excellence in a fas...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Finance & Insurance

$144K - $211K *

Lead the charge in managing complex Industrial Controls workstreams, ensuring seamless execution of NPI programs. Collaborate across teams to deliver innovative automation solutions on time and within...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$76K - $95K *

Join a team that's dedicated to enhancing workplace safety and compliance. As a Senior EHS Specialist, you'll develop policies, conduct audits, and collaborate with engineers to mitigate risks and pro...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$72K - $116K *

Drive optimal health outcomes by managing comprehensive case management services. Assess member needs, develop care plans, coordinate services, and monitor progress to ensure quality, cost-effective h...

Pennsylvania, USRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$142K - $235K *

Deliver strategic leadership in driving sales growth across non-commercial channels. Manage a team to implement innovative strategies, enhance customer partnerships, and achieve financial goals while...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Food & Beverages

$116K - $194K *

Elevate your career by joining a dynamic engineering team focused on ATM and TCR technologies. As a key technical specialist, you'll enhance customer-facing banking services through innovative solutio...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Grow your career with a dynamic role focused on driving sales growth and building strong retail partnerships in the home appliances sector, leveraging your insights and relationships to enhance produc...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $167K *

Join a team that's driving impactful earned media strategies in a dynamic, fast-paced environment. Lead media relations, secure placements, and maintain brand consistency while leveraging AI tools for...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Grow your career with a dynamic role in Optometry, providing comprehensive eye care and leading a dedicated team in a community-focused environment. Enjoy a fulfilling practice without weekend hours w...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $125K *

Join us as an EP Mapping Specialist, where you'll provide clinical and technical support for cardiac mapping solutions, collaborating with healthcare professionals to enhance patient outcomes and driv...

Philadelphia, PARemote

Today

  •   5 - 7 years exp.  •   Healthcare

$120K - $125K *

Lead the charge in transforming cardiac care by providing expert clinical and technical support for mapping and navigation systems, driving innovation and enhancing patient outcomes across multiple ac...

Reposted today

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.