Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,521

Sort By: Relevance

$100K - $120K *

Partner with us to lead financial operations in pharmacy and vaccine programs, ensuring reimbursement accuracy and operational efficiency while collaborating with various departments and external stak...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$185K - $205K *

Shape the future of economic development by leading initiatives that foster a thriving business environment. Collaborate with stakeholders to implement policies that support both small businesses and...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$180K - $220K *

Lead the charge in delivering compassionate psychiatric care through comprehensive evaluation, diagnosis, and treatment, while collaborating with healthcare professionals and supervising psychiatric n...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $375K *

Lead a team that drives operational excellence in Central Processing and High-Level Disinfection Services, ensuring compliance and quality outcomes across a multi-campus healthcare enterprise. Collabo...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Empower forensic laboratories globally by validating cutting-edge DNA technologies. Collaborate with teams to ensure seamless integration of new systems, providing expert training and support to enhan...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Transform complex systems through design, development, and support. Lead innovative projects while ensuring high availability and scalability. Collaborate to enhance technology solutions in a dynamic...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Staffing

$110K - $130K *

Optimize cybersecurity operations by designing and implementing integrations and automation solutions. Collaborate with cross-functional teams to enhance security platforms, improve incident response...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $120K *

Pioneer innovative actuarial solutions that drive profitable growth for clients across key markets. Collaborate on advanced analytics and cutting-edge technology to enhance decision-making and transfo...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Optimize service operations by leading a high-performing team to enhance customer satisfaction, drive efficiency, and achieve departmental goals in a dynamic automotive retail environment...

2 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$85K - $90K *

Join a team that's dedicated to delivering excellence daily, ensuring timely and safe transport of goods while enjoying competitive pay and a supportive work environment with flexible scheduling optio...

2 days ago

  •   Less than 5 years exp.  •   Transportation

$80K - $95K *

Join a team that's dedicated to enhancing operational standards and driving continuous improvement initiatives through lean methodologies and cross-functional collaboration to optimize efficiency and...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform operational standards and procedures by leading continuous improvement initiatives, utilizing lean/Six Sigma methodologies to enhance efficiency, reduce costs, and optimize manufacturing pro...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead the charge in driving growth through strategic partnerships, M&A, and de novo developments. Manage the full business development lifecycle while cultivating relationships with key stakeholders to...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $110K *

Reimagine health plan payment integrity by leading operational projects, analyzing claims data, and collaborating across teams to enhance compliance and financial outcomes. Drive strategic initiatives...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$148K - $214K *

Join a team that's redefining marketing technology strategy and execution. Lead global initiatives, drive innovation with AI, and enhance customer experiences while building a high-performing technica...

2 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$68K - $110K *

Join a dynamic team to coordinate large-engine service projects, ensuring efficient execution and financial tracking. Collaborate with cross-functional teams to enhance service excellence and meet cus...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$200K - $240K *

Lead the charge in Oncology market research, overseeing strategic initiatives, managing a team, and driving business development. Collaborate with clients to deliver insights and foster growth in a fa...

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $100K *

Drive new client acquisition and expansion by building strong relationships, identifying opportunities, and leveraging consultative sales techniques to increase revenue through corporate gifting solut...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$90K - $143K *

Advance your career by supporting client data integration and automation. Collaborate with cross-functional teams to ensure reliable data movement and timely issue resolution, enhancing service delive...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$88K - $105K *

Drive operational excellence in Behavioral Health by overseeing service, product, billing, and vendor management. Collaborate cross-functionally to resolve escalations, ensure compliance, and enhance...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Explore a pivotal role in our Security Operations Center, leading investigations, mentoring junior analysts, and enhancing incident response strategies. Collaborate with teams to refine detection meth...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$138K - $165K *

Lead the charge in driving complex integration programs that connect products and platforms at scale. Collaborate across teams to ensure seamless interoperability and operational excellence, shaping t...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Deliver innovative engineering solutions for power distribution systems, ensuring compliance with standards and regulations. Mentor junior engineers while managing complex projects and collaborating w...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead and oversee substation protection & control engineering for high-voltage projects, ensuring technical quality, compliance with standards, and effective stakeholder collaboration to meet project m...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Transform power distribution systems by leading innovative engineering solutions, mentoring teams, and ensuring compliance with industry standards. Collaborate across functions to deliver projects tha...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.