Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,521

Sort By: Relevance

$120K - $145K *

Lead the charge in transforming complex revenue-cycle challenges into robust, production-ready AI models, ensuring statistical integrity and operational reliability while managing end-to-end data pipe...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Champion client success by driving account growth, managing key relationships, and ensuring satisfaction in the Banking sector. Utilize your IT services expertise and communication skills to achieve s...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Contribute to software solutions by engaging in design discussions, coding, and testing. Collaborate with cross-functional teams to ensure system stability and quality, while maintaining documentation...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Shape innovative HVAC engineering solutions by collaborating with clients and project teams. Apply your expertise to deliver high-quality designs that meet industry standards and enhance efficiency in...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Technical Services

$88K - $105K *

Unlock potential by leading innovative laboratory research and trials to enhance product properties. Collaborate across functions to apply expertise and support continuous improvement within operation...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Lead the growth of strategic partner relationships, driving revenue through effective collaboration and pipeline management. Own a portfolio of partners, ensuring alignment and execution of joint busi...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Develop and execute pharmacy sourcing strategies to optimize supply chain performance, enhance patient care, and reduce costs. Collaborate with teams to manage supplier negotiations, compliance, and a...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Engage in comprehensive psychiatric care as a CRNP, providing evaluations, medication management, and patient education. Collaborate with a multidisciplinary team to enhance mental health outcomes for...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Partner with us to lead financial operations in pharmacy and vaccine programs, ensuring reimbursement accuracy and operational efficiency while collaborating with various departments and external stak...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$185K - $205K *

Shape the future of economic development by leading initiatives that foster a thriving business environment. Collaborate with stakeholders to implement policies that support both small businesses and...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$180K - $220K *

Lead the charge in delivering compassionate psychiatric care through comprehensive evaluation, diagnosis, and treatment, while collaborating with healthcare professionals and supervising psychiatric n...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $375K *

Lead a team that drives operational excellence in Central Processing and High-Level Disinfection Services, ensuring compliance and quality outcomes across a multi-campus healthcare enterprise. Collabo...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Empower forensic laboratories globally by validating cutting-edge DNA technologies. Collaborate with teams to ensure seamless integration of new systems, providing expert training and support to enhan...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Transform complex systems through design, development, and support. Lead innovative projects while ensuring high availability and scalability. Collaborate to enhance technology solutions in a dynamic...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Staffing

$110K - $130K *

Advance data solutions by building and maintaining pipelines, optimizing performance, and ensuring data integrity. Collaborate with cross-functional teams to deliver analytics and reporting data that...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Optimize cybersecurity operations by designing and implementing integrations and automation solutions. Collaborate with cross-functional teams to enhance security platforms, improve incident response...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $120K *

Pioneer innovative actuarial solutions that drive profitable growth for clients across key markets. Collaborate on advanced analytics and cutting-edge technology to enhance decision-making and transfo...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Optimize service operations by leading a high-performing team to enhance customer satisfaction, drive efficiency, and achieve departmental goals in a dynamic automotive retail environment...

2 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$85K - $90K *

Join a team that's dedicated to delivering excellence daily, ensuring timely and safe transport of goods while enjoying competitive pay and a supportive work environment with flexible scheduling optio...

2 days ago

  •   Less than 5 years exp.  •   Transportation

$80K - $95K *

Join a team that's dedicated to enhancing operational standards and driving continuous improvement initiatives through lean methodologies and cross-functional collaboration to optimize efficiency and...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform operational standards and procedures by leading continuous improvement initiatives, utilizing lean/Six Sigma methodologies to enhance efficiency, reduce costs, and optimize manufacturing pro...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead the charge in driving growth through strategic partnerships, M&A, and de novo developments. Manage the full business development lifecycle while cultivating relationships with key stakeholders to...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $110K *

Reimagine health plan payment integrity by leading operational projects, analyzing claims data, and collaborating across teams to enhance compliance and financial outcomes. Drive strategic initiatives...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$148K - $214K *

Join a team that's redefining marketing technology strategy and execution. Lead global initiatives, drive innovation with AI, and enhance customer experiences while building a high-performing technica...

2 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$68K - $110K *

Join a dynamic team to coordinate large-engine service projects, ensuring efficient execution and financial tracking. Collaborate with cross-functional teams to enhance service excellence and meet cus...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.