Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,442

Sort By: Relevance

$117K - $195K *

Advance your career as a Senior Information System Security Engineer, collaborating on critical national security projects. Drive cybersecurity initiatives, develop policies, and enhance cloud securit...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$170K - $210K *

Champion strategic growth by translating executive priorities into actionable plans. Collaborate across functions to drive performance, assess market opportunities, and ensure alignment on corporate o...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$76K - $121K *

Innovate in the design and development of cutting-edge biomedical devices. Collaborate with cross-functional teams to enhance patient care through advanced orthopedic solutions, ensuring compliance an...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $102K *

Lead strategic logistics and operations planning, managing development and execution of projects while analyzing capabilities and risks to ensure operational readiness and support for senior executive...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$121K - $182K *

Partner with us to lead complex cloud migrations, ensuring technical readiness and seamless execution across Azure and AWS environments while driving innovative solutions and high-quality outcomes in...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$154K - $232K *

Transform enterprise cloud strategies by leading large-scale migrations to Azure and AWS. Collaborate with global teams to establish architecture standards, ensure security, and drive innovative solut...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$140K - $211K *

Lead the charge in transforming enterprise applications through cloud migration. Drive global initiatives, mentor teams, and solve complex challenges while ensuring seamless transitions to Azure and A...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$88K - $105K *

Join a dynamic team to ensure compliance with healthcare quality standards, manage credentialing databases, and support operational objectives. Collaborate across departments to enhance quality govern...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Transform project safety through comprehensive oversight, leading teams to implement and sustain effective environmental safety policies across diverse locations while ensuring compliance with all rel...

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the execution of large-scale construction projects, ensuring safety, quality, and budget compliance. Collaborate with stakeholders to navigate challenges and drive project success from planning t...

Reposted today

  •   8 - 10 years exp.  •   Real Estate & Construction

$128K - $196K *

Champion the future of U.S. Navy logistics by integrating maintenance, sustainment, and modernization strategies to enhance operational availability and lifecycle management of surface ships. Collabor...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$80K - $200K *

Engage with small business owners to drive membership growth through face-to-face sales, prospecting, and relationship building. This role emphasizes achieving sales goals while advocating for local b...

Today

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Lead a dynamic recovery team to maximize subrogation efforts across diverse claims, ensuring compliance and quality control while providing expert guidance and training to colleagues for optimal resol...

Pennsylvania, USRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$300K - $350K *

Empower your career by driving sales growth in the cybersecurity sector. Build strong customer relationships, acquire new accounts, and exceed sales quotas while managing Channel Partner relationships...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$300K - $350K *

Accelerate progress at driving sales growth in the cybersecurity sector by acquiring new accounts, building relationships, and ensuring customer satisfaction. Leverage your expertise to exceed quotas...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$63K - $111K *

Join a team that's dedicated to producing high-quality technical documentation. Collaborate with engineers and project teams to create clear, accurate reports while ensuring compliance with standards...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$85K - $95K *

Join a team that's dedicated to effective records management and facilities operations. Leverage your expertise in federal regulations to enhance compliance and streamline processes, ensuring efficien...

Today

  •   5 - 7 years exp.  •   Technical Services

$74K - $99K *

Join a team that's dedicated to enhancing investment outcomes for financial advisors. Collaborate with sales partners and clients to drive the adoption of innovative investment solutions and provide e...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$82K - $141K *

Unlock potential by serving as a trusted HR partner, guiding leaders and employees on employee relations, performance management, and talent processes. Balance consultation and operational execution t...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$195K - $265K *

Transform global marketing strategies in oncology by leading cross-functional teams, driving insights, and optimizing brand value for pipeline assets. Collaborate with stakeholders to enhance commerci...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Innovate and enhance application solutions as a Software Engineer II, driving system implementation and support. Collaborate with users and teams to deliver quality software, ensuring adherence to pro...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$135K - $251K *

Take ownership of software development activities, leading a skilled team in designing, developing, and testing solutions. Collaborate closely with peers and customers while applying agile methodologi...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $130K *

Unlock potential by driving business development in Electronic Warfare, managing relationships with US DoD customers, and expanding market presence through strategic sales initiatives and customer eng...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Aerospace & Defense

$84K - $129K *

Optimize SCADA systems design and implementation for electric grid projects. Engage with clients to develop communication systems, troubleshoot networks, and ensure compliance with NERC standards whil...

Today

  •   5 - 7 years exp.  •   Technical Services

$84K - $129K *

Optimize SCADA systems for electric grid infrastructure. Engage in client projects, design communication systems, and develop automation tools while ensuring compliance with industry standards. Collab...

Today

  •   5 - 7 years exp.  •   Technical Services

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.