Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$120K - $140K *

Engage with cross-functional teams to develop and refine AI/ML models that enhance Therapeutics Development & Supply. Utilize your expertise in data science to deliver impactful analytical solutions t...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in developing innovative AI/ML models that enhance Therapeutics Development & Supply. Collaborate with cross-functional teams to deliver impactful data science solutions, driving scien...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$166K - $200K *

Champion innovative strategies in pharmaceutical sales, leading a high-performing team to drive market access and revenue growth. Collaborate cross-functionally to translate insights into action and e...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$117K - $201K *

Lead the charge in crafting clinical documents for groundbreaking immunology therapies. Manage teams, enhance processes, and mentor junior writers while ensuring regulatory compliance and high-quality...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$96K - $155K *

Partner with us to drive the adoption of innovative digital trauma technologies, ensuring successful installations and customer engagement while achieving sales goals and enhancing clinical education...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $258K *

Shape the future of supply chain management by driving strategic initiatives that enhance customer experience and operational excellence in the Immunology and Neuroscience sectors. Collaborate across...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Explore innovative AI solutions to enhance scientific workflows in Therapeutics Development. Collaborate across teams to design, implement, and evaluate AI-driven applications that support regulatory...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Elevate scientific discovery by transforming complex data into AI-ready assets. Collaborate with cross-functional teams to enhance small-molecule workflows, ensuring data quality and accessibility for...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$196K - $342K *

Unlock your potential in medical safety strategy, leading global teams and overseeing critical risk management activities for solid tumor products to ensure compliance and patient safety...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Lead the charge in integrating AI solutions within Cell and Gene Therapy, driving innovation and collaboration across teams to tackle scientific challenges and enhance R&D processes, ensuring impactfu...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Drive innovation in Cell and Gene Therapy by leading AI solutions that transform scientific challenges into actionable insights, fostering collaboration across teams to enhance R&D capabilities and ac...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform the learning landscape for Immunology field teams by developing impactful training solutions that enhance capabilities and drive performance. Collaborate with experts to create engaging curr...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Unlock potential by leading strategic contract development and management for Provider Channels. Drive team performance, ensure compliance, and translate pricing strategies into actionable agreements...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$93K - $140K *

Manage customer relationships and drive agronomy solutions by leveraging technical expertise. Collaborate with sales teams to enhance product positioning and execute training, while creating new marke...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$107K - $161K *

Drive local seed sales success by training teams, developing agronomy tools, and assessing market needs. Collaborate with sales and agronomy experts to enhance product strategies and execute effective...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$123K - $185K *

Lead K-12 sales initiatives in the Southeast, driving growth through strategic partnerships and culinary collaborations while enhancing product placements and bid success across school districts...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$94K - $164K *

Drive business continuity and disaster recovery initiatives, ensuring critical operations are sustained and services restored post-disruption. Collaborate with stakeholders to assess risks, validate r...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$62K - $100K *

Join a team that's dedicated to delivering successful projects by managing small complexity initiatives, ensuring milestones are met, and fostering collaboration across business and IT stakeholders fo...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$72K - $115K *

Transform the future of digital products by managing their lifecycle, optimizing user experiences, and collaborating with cross-functional teams to drive engagement and adoption while ensuring alignme...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$94K - $164K *

Elevate project outcomes by managing medium to high complexity initiatives, ensuring timely delivery, stakeholder engagement, and adherence to best practices throughout the project lifecycle...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$83K - $132K *

Champion operational excellence by leading compliance and process improvements in Utilization Management. Collaborate across teams to identify gaps, drive change, and ensure adherence to regulatory st...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$265K - $325K *

Shape the future of healthcare data by leading legal, compliance, and contracting functions. Collaborate with executives to integrate teams and drive innovative solutions, fostering a culture of excel...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Accelerate your career by driving revenue growth and building relationships with prospects. Leverage your consultative sales expertise to manage the entire sales pipeline and deliver tailored solution...

3 days ago

  •   5 - 7 years exp.  •   Transportation

$135K - $160K *

Empower your career as a Principal IAM Engineer, owning the identity control plane and ensuring secure access to sensitive data. Collaborate with cross-functional teams to automate identity processes...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$76K - $95K *

Accelerate resident care by delivering skilled nursing services, monitoring health conditions, and collaborating with interdisciplinary teams to ensure high-quality, compassionate care in a supportive...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.