Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $122,395

Sort By: Relevance

$190K - $300K *

Unlock your potential by leading strategic initiatives in global scientific content development. Collaborate with cross-functional teams to enhance oncology payer engagement and drive impactful traini...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $300K *

Lead biostatistical initiatives in drug and vaccine projects, collaborating across teams to ensure effective trial designs and regulatory compliance. Drive statistical analysis and innovative research...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$255K - $402K *

Shape the future of oncology by leading strategic payer engagement and health systems initiatives. Drive execution of medical affairs plans while mentoring a high-performing team to enhance access and...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$142K - $224K *

Support the implementation of global Site Budgets & Payments strategies, ensuring effective regional execution and governance. Collaborate with cross-functional teams to enhance operational excellence...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$142K - $224K *

Transform operational strategy and execution across a high-impact organization, leading governance, resource management, and cross-functional alignment to drive consistent and compliant outcomes while...

North Wales, PARemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Drive strategic account management within Integrated Delivery Systems, enhancing relationships and optimizing product access across New York's healthcare landscape. Collaborate with stakeholders to ac...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K - $331K *

Lead the charge in safety and risk management processes, ensuring compliance and continuous improvement across departments. Collaborate with stakeholders to develop metrics and oversee pharmacovigilan...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$142K - $224K *

Empower cross-functional teams to develop and implement pharmacovigilance strategies, ensuring compliance and patient safety while managing product backlogs and stakeholder relationships in a dynamic...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K - $137K *

Optimize the production of live virus vaccines by leading investigations and process improvements. Collaborate with cross-functional teams to troubleshoot issues and ensure compliance with GMP standar...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$65K - $102K *

Join us to manage demand planning and supply chain processes, ensuring accuracy and efficiency in inventory management. Collaborate across teams to optimize customer service and achieve operational ex...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$87K - $137K *

Optimize manufacturing processes by providing automation expertise, troubleshooting issues, and implementing strategies to enhance efficiency and compliance in vaccine production, ensuring quality sup...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $100K *

Unlock potential by driving sales of pest management solutions to residential customers. Collaborate with teams to assess needs, provide expert consultations, and enhance customer satisfaction while m...

3 days ago

  •   Less than 5 years exp.  •   Business Services

$185K - $297K *

Innovate the future of software delivery by defining technical direction for a vital platform. Lead high-impact projects, set architecture standards, and mentor engineers in this hands-on role within...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Help us lead and optimize global Order-to-Cash operations, overseeing billing, collections, and accounts receivable. Drive cross-functional partnerships, enhance workflows, and manage a high-performin...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$111K - $167K *

Drive impactful marketing strategies by leveraging data analysis and AI tools. Collaborate cross-functionally to enhance funnel performance, ROI modeling, and operational efficiency, ensuring alignmen...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$290K - $436K *

Elevate our mobile engineering organization by leading teams, driving modernization, and ensuring app performance and quality. Collaborate with cross-functional partners to innovate and mentor future...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$75K - $103K *

Transform fleet operations by overseeing compliance, safety, and efficiency. Collaborate with drivers and suppliers to enhance vehicle performance and reduce downtime while managing budgets and improv...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$82K - $170K *

Empower field marketing teams by managing vendor relationships and operational processes. Own the infrastructure that supports effective execution, ensuring compliance and efficiency across diverse ma...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Transportation

$71K - $129K *

Join a dynamic sales team to drive new business growth by acquiring small business accounts. Utilize solution-based selling techniques to meet sales quotas while developing your skills for career adva...

3 days ago

  •   Less than 5 years exp.  •   Transportation

$145K - $190K *

Drive operational excellence and fiscal performance across Northeast Airfreight and Canada stations, ensuring strategic growth, compliance, and superior customer experience while leading diverse teams...

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$132K - $271K *

Join a team that's driving innovation in pre-sales support for complex software solutions. Leverage your expertise to deliver impactful product demonstrations, engage with clients, and enhance the sal...

3 days ago

  •   8 - 10 years exp.  •   Business Services

$94K - $293K *

Transform the security operations landscape by leading SOC modernization initiatives, enhancing client capabilities against AI-driven threats, and mentoring teams to deliver innovative solutions that...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$132K - $271K *

Drive pre-sales excellence by delivering tailored software demos, supporting complex sales cycles, and collaborating with clients and partners to enhance solution delivery and asset development across...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Business Services

$132K - $271K *

Transform complex software sales cycles by delivering impactful demos, responding to client needs, and developing reusable pre-sales assets. Collaborate with teams to enhance pipeline conversion and s...

3 days ago

  •   8 - 10 years exp.  •   Business Services

$70K - $196K *

Unlock innovative robotics solutions by leading interdisciplinary teams to develop scalable AI architectures and enhance industrial applications. Collaborate with experts to tackle complex challenges...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.