Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.
Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.
Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.
Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.
Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.
Average Salary: $122,395
Global Scientific & Value Content and Implementation - Payor
$190K - $300K *
Unlock your potential by leading strategic initiatives in global scientific content development. Collaborate with cross-functional teams to enhance oncology payer engagement and drive impactful traini...
3 days ago
Principal Scientist, Biostatistics, Late-Stage Clinical Development
$190K - $300K *
Lead biostatistical initiatives in drug and vaccine projects, collaborating across teams to ensure effective trial designs and regulatory compliance. Drive statistical analysis and innovative research...
Reposted 3 days ago
US Executive Director of Medical Affairs, Payer & Health Systems (PHS EDMA) Oncology
$255K - $402K *
Shape the future of oncology by leading strategic payer engagement and health systems initiatives. Drive execution of medical affairs plans while mentoring a high-performing team to enhance access and...
3 days ago
Site Budgets & Payments Operational Excellence Regional Lead
$142K - $224K *
Support the implementation of global Site Budgets & Payments strategies, ensuring effective regional execution and governance. Collaborate with cross-functional teams to enhance operational excellence...
3 days ago
Associate Director, Oncology KARE Operations & Strategic Execution
$142K - $224K *
Transform operational strategy and execution across a high-impact organization, leading governance, resource management, and cross-functional alignment to drive consistent and compliant outcomes while...
3 days ago
Health Care Systems - Integrated Account Leader
$173K - $272K *
Drive strategic account management within Integrated Delivery Systems, enhancing relationships and optimizing product access across New York's healthcare landscape. Collaborate with stakeholders to ac...
3 days ago
Sr. Principal Scientist (Sr. Director) , Drug Safety
$210K - $331K *
Lead the charge in safety and risk management processes, ensuring compliance and continuous improvement across departments. Collaborate with stakeholders to develop metrics and oversee pharmacovigilan...
3 days ago
Associate Director, Technical Product Management
$142K - $224K *
Empower cross-functional teams to develop and implement pharmacovigilance strategies, ensuring compliance and patient safety while managing product backlogs and stakeholder relationships in a dynamic...
3 days ago
$87K - $137K *
Optimize the production of live virus vaccines by leading investigations and process improvements. Collaborate with cross-functional teams to troubleshoot issues and ensure compliance with GMP standar...
3 days ago
2027 Future Talent Program - Associate Specialist Supply Chain Management
$65K - $102K *
Join us to manage demand planning and supply chain processes, ensuring accuracy and efficiency in inventory management. Collaborate across teams to optimize customer service and achieve operational ex...
Reposted 3 days ago
Specialist, Manufacturing Automation
$87K - $137K *
Optimize manufacturing processes by providing automation expertise, troubleshooting issues, and implementing strategies to enhance efficiency and compliance in vaccine production, ensuring quality sup...
3 days ago
$70K - $100K *
Unlock potential by driving sales of pest management solutions to residential customers. Collaborate with teams to assess needs, provide expert consultations, and enhance customer satisfaction while m...
3 days ago
Staff Software Engineer, Platform (DevEx)
$185K - $297K *
Innovate the future of software delivery by defining technical direction for a vital platform. Lead high-impact projects, set architecture standards, and mentor engineers in this hands-on role within...
Reposted 3 days ago
Director of Billing and Collections
$150K - $180K *
Help us lead and optimize global Order-to-Cash operations, overseeing billing, collections, and accounts receivable. Drive cross-functional partnerships, enhance workflows, and manage a high-performin...
3 days ago
Senior Analyst, Marketing Strategy & Operations
$111K - $167K *
Drive impactful marketing strategies by leveraging data analysis and AI tools. Collaborate cross-functionally to enhance funnel performance, ROI modeling, and operational efficiency, ensuring alignmen...
3 days ago
Senior Director, Software Engineering
$290K - $436K *
Elevate our mobile engineering organization by leading teams, driving modernization, and ensuring app performance and quality. Collaborate with cross-functional partners to innovate and mentor future...
3 days ago
Fleet Manager (Midland, Texas)
$75K - $103K *
Transform fleet operations by overseeing compliance, safety, and efficiency. Collaborate with drivers and suppliers to enhance vehicle performance and reduce downtime while managing budgets and improv...
3 days ago
Sr Regional Marketing Manager: Marketing Operations & Field Programs Manager
$82K - $170K *
Empower field marketing teams by managing vendor relationships and operational processes. Own the infrastructure that supports effective execution, ensuring compliance and efficiency across diverse ma...
3 days ago
Account Executive, Business Team Sales - Lehigh Valley, PA/Western NJ
$71K - $129K *
Join a dynamic sales team to drive new business growth by acquiring small business accounts. Utilize solution-based selling techniques to meet sales quotas while developing your skills for career adva...
3 days ago
District Air Manager NE & Air Station Manager – Canada
$145K - $190K *
Drive operational excellence and fiscal performance across Northeast Airfreight and Canada stations, ensuring strategic growth, compliance, and superior customer experience while leading diverse teams...
3 days ago
Software Product Pre Sales Engineer Senior Manager - FinCrime
$132K - $271K *
Join a team that's driving innovation in pre-sales support for complex software solutions. Leverage your expertise to deliver impactful product demonstrations, engage with clients, and enhance the sal...
3 days ago
SecOps Modernization & Agentic SOC Manager
$94K - $293K *
Transform the security operations landscape by leading SOC modernization initiatives, enhancing client capabilities against AI-driven threats, and mentoring teams to deliver innovative solutions that...
3 days ago
Software Product Management Pre Sales Senior Manager - Consumer Goods & Services
$132K - $271K *
Drive pre-sales excellence by delivering tailored software demos, supporting complex sales cycles, and collaborating with clients and partners to enhance solution delivery and asset development across...
Reposted 3 days ago
Software Product Pre Sales Engineer Senior Manager - FinCrime
$132K - $271K *
Transform complex software sales cycles by delivering impactful demos, responding to client needs, and developing reusable pre-sales assets. Collaborate with teams to enhance pipeline conversion and s...
3 days ago
$70K - $196K *
Unlock innovative robotics solutions by leading interdisciplinary teams to develop scalable AI architectures and enhance industrial applications. Collaborate with experts to tackle complex challenges...
Reposted 3 days ago
What kinds of high-paying jobs can I find in Pennsylvania?
Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.
Do Pennsylvania jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.
How can I narrow my search for jobs in Pennsylvania?
Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.
Are remote or hybrid jobs available in Pennsylvania?
Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.