Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Director, Advanced Analytics and Modeling - Key Drivers & Actions (KDA)
$194K - $361K *
Reimagine your career by leading advanced analytics initiatives that drive enterprise performance. Collaborate across functions to translate insights into strategic actions, enhancing growth and marke...
Today
Director, Client Coding Integration
$97K - $145K *
Lead strategic client coding integration initiatives, ensuring alignment with corporate objectives and regulatory compliance while driving operational excellence and innovation across the revenue cycl...
Reposted yesterday
$110K - $130K *
Empower your career by leading a dynamic team of Client Success Managers, driving customer satisfaction and retention while collaborating cross-functionally to maximize value from our solutions and in...
3 weeks ago
$135K - $151K *
Drive product strategy and execution for Patient Experience solutions, enhancing healthcare practices' connection with patients. Lead cross-functional teams, leverage AI, and optimize workflows to imp...
Today
Senior Analyst, Medical Economics - UM Analytics (Remote)
$90K - $110K *
Drive impactful medical economics analysis by extracting and synthesizing data to identify trends, enhance financial performance, and support executive decision-making across healthcare operations and...
3 weeks ago
Senior Director, US Marketing, Inborn Errors of Metabolism
$247K - $305K *
Support the strategic commercialization of rare disease therapies by leading marketing initiatives, collaborating cross-functionally, and optimizing brand strategies to enhance patient access and enga...
Reposted yesterday
Managing Consultant, Life Sciences Technology Consulting - Patient Services
$130K - $216K *
Join a dynamic team to lead technology consulting projects in biopharma, ensuring successful implementation of patient services solutions. Collaborate with clients and cross-functional teams to drive...
1 week ago
Senior Director, Global Enablement
$225K - $324K *
Accelerate growth by leading global enablement initiatives that empower sellers, engineers, and partners. Drive strategic programs, enhance skills, and ensure readiness for a multi-product platform in...
1 week ago
$80K - $110K *
Transform financial operations by providing analytical support, enhancing reporting processes, and collaborating with cross-functional teams to drive profitability and efficiency in budgeting and fore...
2 days ago
$150K - $215K *
Champion strategic sales initiatives by leading a high-performing pod, driving complex SaaS partnerships with top law firms, and fostering executive-level relationships to enhance client engagement an...
2 weeks ago
$110K - $130K *
Empower transformative telehealth solutions by designing and implementing robust software infrastructure. Join a dynamic team to innovate, automate, and streamline applications, impacting the healthca...
Reposted today
Director, GLP-1 & Cardiometabolic Product Marketing
$194K - $242K *
Unlock potential by leading product marketing strategies in GLP-1 and cardiometabolic health. Collaborate with cross-functional teams to enhance buyer clarity and sales effectiveness, while coaching a...
6 days ago
Regulatory Affairs Consultant, CMC - Biologics
$110K - $130K *
Drive your career with a pivotal role in CMC regulatory affairs, ensuring compliance for biologics and small molecules. Collaborate across teams to prepare high-quality submissions and strategies, imp...
Yesterday
$160K - $200K *
Drive the M&A strategy by leading the full transaction lifecycle, from sourcing to integration. Collaborate with executive leadership to identify growth opportunities that enhance enterprise value and...
2 weeks ago
$160K - $170K *
Transform your career by leading a dedicated pharmacy team, ensuring operational excellence, and fostering patient relationships in a supportive community environment. Enjoy competitive compensation a...
1 week ago
$120K - $160K *
Analyze complex data and drive solutions as a Business Analyst in the public sector. Leverage your expertise in pension systems to identify issues and enhance processes, ensuring effective communicati...
Reposted 4 days ago
$95K - $105K *
Join a dynamic team to coordinate supplier management, drive contract workflows, and ensure compliance in clinical studies. Collaborate with cross-functional teams to enhance supplier processes and su...
Yesterday
$150K - $240K *
Optimize coding workflows by leveraging your 10+ years of leadership in coding, compliance, and revenue cycle management. Collaborate with AI and engineering teams to drive innovation and enhance oper...
1 week ago
$80K - $95K *
Drive financial accuracy and compliance as a Senior Accountant. Lead month-end close, maintain internal controls, and support auditors while refining processes. Ideal for proactive self-starters seeki...
Reposted 4 weeks ago
$215K - $240K *
Shape the future of commercial operations by leading strategy, workflows, and data integration. Collaborate with senior leaders to enhance brand performance and drive operational excellence across cro...
3 weeks ago
Occupational Therapist - Full-time
$62K - $112K *
Empower patients on their recovery journey by delivering compassionate occupational therapy. Collaborate with healthcare teams to create tailored treatment plans and supervise support staff, ensuring...
2 weeks ago
Medical Safety Manager, Ambulatory Monitoring & Diagnostics
$133K - $237K *
Contribute to patient safety by overseeing medical product surveillance, analyzing data, and ensuring compliance with regulations. Collaborate on risk management and support clinical studies to enhanc...
1 week ago
Forward Deployed Engineer (Mid/Senior) - Remote w/Travel
$120K - $145K *
Transform healthcare through innovative AI deployments. As a key technical expert, you'll develop and implement cutting-edge systems that enhance clinical workflows and optimize patient interactions...
4 weeks ago
$80K - $120K *
Shape your career as you take ownership of key accounts, driving sales and building relationships. Collaborate with top performers to modernize government services, while gaining invaluable experience...
2 days ago
$139K - $163K *
Advance your career as a strategic legal partner by providing product and privacy counsel that balances compliance with innovation. Collaborate across teams to develop scalable solutions that support...
Reposted 4 weeks ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.