Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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Oncologist Jobs in Iowa

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$134K - $306K *

Elevate customer engagement by developing and executing strategic study plans, leading cross-functional teams, and ensuring successful project delivery in the rare disease therapeutic area...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $250K *

Make your mark at the forefront of clinical operations, driving global studies from strategy to execution while ensuring operational integration across teams and vendors for successful Phase 3 program...

United StatesRemote

1 month ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$136K - $220K *

Unlock project management excellence in Global Regulatory Affairs, driving timelines and compliance for drug submissions. Collaborate cross-functionally to ensure accurate documentation and effective...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$199K - $370K *

Optimize your sales expertise by driving revenue in state government sectors. Leverage your knowledge of procurement processes to build relationships and close deals, while collaborating with a top-ti...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Media

$98K - $147K *

Empower success by leading strategic programs that enhance clinical, financial, and operational outcomes. Collaborate with teams to optimize processes and ensure alignment with organizational goals, d...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $230K *

Lead the accounting and financial reporting functions within a growing healthcare organization. Drive integrity across multiple entities, ensure compliance, and strategize cash management while suppor...

United StatesRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Healthcare

$200K - $230K *

Champion a transformative member software experience, guiding strategy and design across the care journey. Leverage data and user insights to drive impactful solutions in a complex healthcare landscap...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$149K - $299K *

Champion exceptional service delivery by leading Help Desk operations, ensuring high-quality support for members and stakeholders. Drive continuous improvement, operational excellence, and effective i...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$72K - $107K *

Join a team that's dedicated to enhancing resident development through effective program management, collaboration with clinical leaders, and innovative professional development sessions to ensure a s...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$138K - $191K *

Shape the future of legal operations by managing complex investigations and litigation. Provide expert legal counsel, mitigate risk, and partner with stakeholders to communicate complex issues effecti...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K *

Advance your career by auditing outpatient and specialty claims, ensuring coding accuracy and compliance. Leverage your clinical and coding expertise to enhance audit processes and contribute to quali...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $140K *

Drive the development of predictive analytics models to enhance digital assessment operations, collaborating across teams to optimize decision-making and reduce costs while supporting strategic goals...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$160K - $200K *

Transform client relationships by driving business growth, securing profitable projects, and leveraging market access expertise. Lead teams to exceed expectations while identifying industry trends and...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$89K - $136K *

Innovate clinical application support to enhance patient care efficiency. Manage software upgrades, coordinate with IT teams, and lead projects while ensuring compliance and effective communication ac...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$85K - $100K *

Shape the future of clinical trials by managing supply chain activities, ensuring timely delivery of essential materials and maintaining regulatory compliance. Collaborate with diverse teams to enhanc...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$89K - $155K *

Engage with healthcare professionals to drive product utilization and enhance patient care. This role involves building relationships, delivering clinical knowledge, and executing marketing strategies...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $105K *

Optimize healthcare support by serving as the primary contact for clinical application issues. Collaborate with clinicians and IT teams to troubleshoot, educate, and resolve technical challenges, ensu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$174K - $374K *

Engage with patients in their homes to conduct health evaluations, build relationships, and bridge care gaps. This role demands extensive travel and flexibility to provide personalized care and diagno...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive enterprise-level revenue growth by building relationships with healthcare executives, identifying strategic opportunities, and delivering tailored solutions to meet sales goals in a dynamic heal...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$115K - $125K *

Drive the development and management of virtual health services, enhancing operational excellence and patient experience while scaling innovative care models across the organization. Lead strategic in...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$75K - $110K *

Optimize the claims resolution process for commercial property and casualty claims. Collaborate with internal teams and stakeholders to enhance claims handling efficiency and effective communication...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$180K - $215K *

Lead the charge in driving regional sales success through strategic execution, team leadership, and cross-functional collaboration. Foster strong customer relationships and ensure alignment with corpo...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$103K - $128K *

Join us to lead product strategy and development, driving innovation and performance in healthcare solutions. Collaborate cross-functionally to align business needs with customer expectations and ensu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Take ownership of complex desktop and mobile device support, ensuring high customer satisfaction. Administer enterprise management platforms and collaborate with teams to deliver effective technology...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Transform endpoint management by leading complex support initiatives, ensuring seamless service delivery across diverse environments. Collaborate with teams to enhance user experience and optimize tec...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.