Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs offering salaries of $100,000 or more, from leadership positions to specialized roles. Whether you’re targeting a new opportunity in Columbus, Cleveland, Cincinnati, or another Ohio community, find openings that match your experience and career goals.

Find Opportunities Across Ohio

Ohio’s job market spans major metropolitan areas and a wide range of industries. Search roles in cities such as Columbus, Cleveland, and Cincinnati, as well as opportunities throughout the state. Availability varies by employer and location, so explore current listings to see where your skills are in demand.

Explore Professional Roles and Industries

High-paying Ohio openings may include positions in technology, healthcare, finance, manufacturing, sales, and operations. Listings can range from experienced individual-contributor roles to director, vice president, and executive positions. Review each posting for its responsibilities, qualifications, location, and compensation details.

Make Your Ohio Job Search More Focused

Use Ladders to narrow your search by role, location, and other preferences. Tailor your resume to highlight relevant achievements, leadership experience, and measurable results. Check listings regularly and apply to opportunities that align with your qualifications and compensation expectations.

Discover Your Next Career Move

Find vetted professional jobs paying $100,000 or more in Ohio on Ladders. Browse current openings and take the next step toward a role that fits your experience and ambitions.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $124,757

Sort By: Relevance

$105K - $110K *

Unlock your potential as you drive strategic growth in K-12 special education markets. Lead complex sales cycles, build trusted relationships, and shape innovative solutions that enhance educational o...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Join a dynamic team to lead store operations, drive sales, enhance customer service, and develop talent across multiple locations, ensuring operational excellence and strategic growth in a fast-paced...

Today

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$117K - $184K *

Shape the future of patient access by collaborating cross-functionally to address healthcare professionals' needs, ensuring timely therapy access while navigating reimbursement processes and complianc...

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  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Lead the charge in ensuring quality oversight for contract testing laboratories globally, implementing policies and managing performance to meet regulatory standards while safeguarding patient safety...

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  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $190K *

Deliver innovative solutions by acquiring Fortune 500 clients, leading complex sales cycles, and building executive relationships. Drive value through AI insights and strategic partnerships, ensuring...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Enterprise Technology

$90K - $105K *

Advance your career by leading a dedicated team in delivering trauma-informed care for substance use disorders. Shape clinical practices and foster a supportive environment in a new clinic focused on...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$100K *

Grow your career by driving business development in the leasing real estate sector. Engage with property management firms to sell essential support services, manage full sales cycles, and foster lasti...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$164K - $225K *

Develop and execute patient advocacy strategies, engaging with PAOs and cross-functional teams to elevate the patient voice and ensure successful partnerships for rare disease therapeutic areas...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$65K - $105K *

Discover a dynamic role where you'll collaborate with teams to design and deploy innovative data-driven solutions, enhancing efficiency and profitability across the insurance lifecycle through advance...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $160K *

Optimize strategic opportunities by leading cross-functional initiatives and applying AI-driven solutions to enhance business performance, while collaborating with senior leaders to drive impactful ch...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$107K - $171K *

Shape the market narrative for AI Agent Identity by leading product marketing initiatives. Own positioning, messaging, and commercial enablement for DNSid, translating complex innovations into compell...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$150K - $347K *

Shape the future of knowledge engineering by owning methodologies, assets, and technical perspectives in AI-driven environments. Lead enterprise knowledge services and engage with stakeholders to driv...

Today

  •   8 - 10 years exp.  •   Business Services

$137K - $219K *

Elevate IT operations by orchestrating complex initiatives, driving user adoption, and optimizing delivery processes. Serve as the key liaison among technical teams and business stakeholders to ensure...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $347K *

Champion your expertise in knowledge engineering by leading ontology creation, managing asset portfolios, and shaping technical perspectives in AI. Drive innovation and influence stakeholders while ow...

Today

  •   8 - 10 years exp.  •   Business Services

$150K - $347K *

Champion the future of knowledge engineering by owning methodologies, asset portfolios, and technical viewpoints. Drive innovation in ontology creation and semantic layers while influencing stakeholde...

Today

  •   8 - 10 years exp.  •   Business Services

$138K - $163K *

Drive the evolution of software solutions for healthcare quality reporting, leading engineering teams to deliver innovative, high-quality products while fostering a culture of collaboration and contin...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$141K - $278K *

Engage with us to transform supply chain networks through strategic design and optimization. Lead end-to-end projects, collaborate with senior leaders, and drive operational excellence to enhance clie...

Today

  •   5 - 7 years exp.  •   Business Services

$141K - $278K *

Shape transformative supply chain strategies, leading end-to-end network design and optimization projects. Collaborate with senior leaders to enhance operational efficiency and drive client success th...

Today

  •   5 - 7 years exp.  •   Business Services

$150K - $200K *

Lead client engagements by leveraging tax expertise to drive revenue growth, manage complex planning discussions, and enhance client relationships while ensuring strategic alignment across teams for o...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $200K *

Lead a dynamic team of Equipment Sales Specialists to drive sales growth, enhance customer satisfaction, and innovate equipment offerings in the dental sector while collaborating with cross-functional...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$79K - $102K *

Champion customer success by guiding Mid-Market clients through the deployment and adoption of IoT solutions, ensuring they maximize value from our technology while building strong relationships acros...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Drive strategic insights by analyzing cross-functional data to enhance decision-making. Collaborate with teams to build a trusted business intelligence framework, delivering actionable recommendations...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Unlock the potential of seamless data exchange by analyzing EDI requirements, developing maps, and supporting integrations. Collaborate with partners to ensure efficient transactions and enhance elect...

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  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that's focused on driving growth in Healthcare and Financial Services. Leverage your enterprise sales expertise to build relationships, develop new business, and deliver impactful technolo...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Lead the charge in enhancing patient care by managing oncology services, collaborating with teams to achieve strategic goals, and ensuring superior medical outcomes in a dynamic healthcare environment...

Today

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Ohio listings may include professional, senior, leadership, and executive roles across fields such as technology, healthcare, finance, manufacturing, sales, and operations. Available positions vary, so check current postings for details.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Opportunities may be available in Columbus, Cleveland, Cincinnati, and other Ohio communities. Search by location to see current openings near you or in a city where you’d like to work.

  • How can I find Ohio jobs that pay at least $100,000?question toggle

    Browse Ohio listings on Ladders and review each posting’s compensation information, location, and qualifications. Use available search filters to focus on roles that fit your experience and goals.

  • Are all Ohio jobs on Ladders remote or on-site?question toggle

    Work arrangements vary by employer and position. Review each listing for its location and whether it describes the role as on-site, hybrid, or remote.