Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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Jobs in Ohio

Average Salary in USD

Average Salary: $124,752

Sort By: Relevance

$70K - $105K *

Collaborate with cross-functional teams to enhance EHR workflows, improve operations, and optimize patient care through effective configuration and analysis of Professional Billing Claims applications...

US-AnywhereRemote

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  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$175K - $225K *

Join a team that's dedicated to delivering innovative tax solutions for sophisticated real estate clients. Lead engagements, mentor staff, and navigate complex tax matters while building strong client...

Today

  •   8 - 10 years exp.  •   Legal & Accounting

$99K - $129K *

Join a team that's transforming nonprofit organizations through expert financial management. As an Accounting Manager/Controller, you'll lead financial planning, reporting, and compliance, ensuring ou...

US-AnywhereRemote

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  •   5 - 7 years exp.  •   Legal & Accounting

$280K - $481K *

Join a team that's driving growth in advanced therapeutics through strategic leadership, P&L accountability, and innovative business development. Shape the future of RNA oligonucleotide manufacturing...

US-AnywhereRemote

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  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$163K - $306K *

Champion the future of laboratory innovation by leading global product strategy, connecting emerging technologies and customer insights to drive impactful business initiatives across diverse markets...

US-AnywhereRemote

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  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$116K - $219K *

Unlock your potential as a senior contributor in software quality engineering, driving high-quality solutions through collaboration, automation, and Agile practices. Enhance product reliability and ef...

US-AnywhereRemote

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$159K - $319K *

Join a team that's driving innovation in Atomic Spectroscopy sales. Leverage your technical expertise to build relationships and create opportunities across commercial, government, and academic sector...

US-AnywhereRemote

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K *

Join a dynamic team to drive the adoption of innovative vascular therapies, expanding market share through strategic account development and training. This role requires proactive engagement with heal...

US-AnywhereRemote

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  •   8 - 10 years exp.  •   Healthcare

$143K *

Champion innovative healthcare solutions by driving adoption of AI-powered technologies in gastrointestinal care. Collaborate with healthcare systems to enhance patient outcomes and operational effici...

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  •   5 - 7 years exp.  •   Healthcare

$90K *

Champion innovative surgical solutions by driving market growth in stapling technologies and robotic procedures. Collaborate with teams to enhance surgical expertise and execute strategic programs for...

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  •   Less than 5 years exp.  •   Healthcare

$107K - $204K *

Join a team that's driving digital transformation by managing program engagements, overseeing project execution, and collaborating across functions to ensure timely delivery of secured work environmen...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$86K - $165K *

Drive project success by leading engineering initiatives for commercial wheel and brake products. Oversee planning, execution, and risk management to ensure timely delivery and optimization of product...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$86K - $165K *

Optimize transportation operations by ensuring efficient shipment processing, inventory management, and order fulfillment. Collaborate with cross-functional teams to meet customer needs and enhance se...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$107K - $204K *

Pioneer innovative contracting solutions in a dynamic environment. Leverage your expertise in U.S. Government and commercial contracts to drive success within integrated project teams while ensuring c...

US-AnywhereRemote

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  •   5 - 7 years exp.  •   Aerospace & Defense

$107K - $204K *

Transform customer delivery performance through data analysis and cross-functional collaboration. Ensure commitments are met by monitoring orders, reporting metrics, and serving as a key contact for d...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$107K - $204K *

Champion supplier quality and development processes, driving continuous improvement and sustainability. Leverage expertise to manage supplier performance, resolve quality issues, and implement strateg...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Aerospace & Defense

$81K - $143K *

Inspire product innovation by bridging business needs and Agile teams, driving strategic product direction and delivery of high-value solutions that align with enterprise goals and enhance customer sa...

US-AnywhereRemote

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  •   5 - 7 years exp.  •   Real Estate & Construction

$82K - $131K *

Drive comprehensive audits and enhance internal controls across business units. Collaborate with stakeholders to assess risks, implement improvements, and ensure compliance while leading audit engagem...

US-AnywhereRemote

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  •   Less than 5 years exp.  •   Real Estate & Construction

$57K - $108K *

Champion the delivery of drafting services by creating detailed piping drawings and BIM models, managing multiple projects, and collaborating with clients to ensure high-quality standards in a dynamic...

US-AnywhereRemote

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  •   Less than 5 years exp.  •   Real Estate & Construction

$76K - $167K *

Advance business development initiatives across the West Coast by building strong relationships, managing accounts, and driving sales growth in the pumps and process equipment market for municipal pro...

US-AnywhereRemote

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  •   5 - 7 years exp.  •   Real Estate & Construction

$54K - $135K *

Design innovative fire sprinkler systems by analyzing building plans and specifications. Collaborate on equipment selection and optimize designs using cutting-edge software. Ensure compliance with saf...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$100K *

Join a team that's shaping the future of healthcare! This 12-month paid fellowship empowers new nurse practitioners to excel in adult primary care, focusing on quality care for older adults through in...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$54K - $116K *

Join a team that's committed to enhancing member wellness through integrated case management and clinical expertise. Leverage your nursing skills to assess, plan, and coordinate care while working fle...

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$124K - $158K *

Advance patient care by leading pharmacy operations, ensuring safety, and fostering a culture of excellence. Collaborate with the team to enhance health outcomes through compassionate service and effe...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$83K - $222K *

Join a dynamic engineering team to design and implement robust software solutions that enhance clinical care delivery. Lead complex projects, mentor engineers, and ensure high-quality, maintainable sy...

US-AnywhereRemote

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  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.