Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,696
$126K - $150K *
Champion growth strategies for net-new business, driving critical sales across cyber threat intelligence. Influence Fortune 1000 leaders in high-stakes environments while navigating complex sales cycl...
Reposted 5 days ago
$100K - $120K *
Engage with cross-functional teams to drive clinical trial success across regions. Leverage your expertise in project management and mentoring to ensure compliance, quality, and timely execution of st...
5 days ago
Independent Software Vendor -Business Development Manager
$110K - $130K *
Grow strategic partnerships and drive revenue through collaboration with Independent Software Vendors (ISVs), ensuring alignment on business objectives and go-to-market strategies to enhance customer...
5 days ago
Senior Full Stack Software Engineer
$130K - $160K *
Unlock your potential as a Senior Full Stack Software Engineer, leading impactful projects and shaping technology solutions. Collaborate across web applications, backend services, and cloud infrastruc...
5 days ago
$80K - $95K *
Advance your career by overseeing geostructural projects, ensuring quality and safety while managing teams and resources across diverse construction environments. Collaborate with clients to develop i...
5 days ago
$79K - $118K *
Champion patient care by collaborating with multidisciplinary teams to identify barriers, enhance engagement, and ensure seamless transitions. Leverage clinical expertise to optimize outcomes and deli...
Reposted 5 days ago
$90K - $120K *
Drive revenue growth by optimizing systems and processes across Marketing, Sales, and Customer Success. Leverage data to enhance operational efficiency and establish HubSpot as a reliable source of tr...
5 days ago
$150K - $180K *
Lead the charge in AI innovation within our Insurance portfolio, overseeing the full lifecycle of solutions from ideation to production. Shape strategy, manage multidisciplinary teams, and build new c...
5 days ago
Senior Director, Business Development
$169K - $255K *
Shape the future of personalized consumer products by driving strategic partnerships and revenue growth. Lead business development efforts, cultivate relationships, and expand market reach to position...
5 days ago
Corporate Director of New Development & Campus Living - Navion Senior Solutions
$110K - $130K *
Lead the development of innovative Campus Living properties, overseeing all phases from planning to operations. Drive financial success and quality standards while collaborating with teams across the...
5 days ago
Senior Site Contracts Manager (Sponsor Dedicated /Remote - US Based)
$79K - $139K *
Join a team that's dedicated to driving excellence in clinical trial contracts. As a Senior Site Contracts Manager, you'll negotiate and manage site budgets and agreements, collaborating with key stak...
5 days ago
Sr. / Principal Medical Writer (Regulatory focus) - Sponsor-dedicated; NA/CAN/UK
$110K - $130K *
Advance your career by leading medical writing projects in a regulatory environment. Collaborate with cross-functional teams to produce high-quality documents, ensuring compliance with industry standa...
5 days ago
$75K - $90K *
Accelerate your career by leading a dynamic restaurant team, driving sales growth, and ensuring exceptional customer service in a fast-paced environment. Enjoy competitive pay, robust benefits, and a...
5 days ago
$75K - $90K *
Shape the future of dining by leading a dynamic team in a fast-paced environment. Drive sales growth and enhance customer experiences while enjoying competitive pay and robust benefits. Join us to mak...
5 days ago
$110K - $130K *
Partner with us to drive transformative healthcare solutions by managing key accounts, fostering relationships, and ensuring measurable outcomes. Your expertise will enhance provider partnerships and...
5 days ago
$80K - $95K *
Transform the future of brand engagement by leading impactful events that elevate visibility and strengthen customer relationships. Your expertise will drive marketing success through strategic planni...
5 days ago
$120K - $150K *
Join a dynamic team as a compliance leader, overseeing U.S. Credit & Fraud Risk operations. Drive compliance initiatives, manage risk assessments, and collaborate with stakeholders to ensure adherence...
5 days ago
AI Security Architect - Generative AI, LLM Security & AI Gateway Controls
$135K - $160K *
Transform your career by leading AI security architecture initiatives. Collaborate globally to design robust security frameworks for generative AI applications, ensuring compliance and operational res...
5 days ago
$80K - $95K *
Drive compliance initiatives by managing environmental permits and programs, ensuring adherence to regulations while advising internal teams. Collaborate with management to enhance compliance procedur...
Reposted 5 days ago
Data Security Support Analyst (Varonis / Entra ID)
$95K - $115K *
Join a dynamic team to enhance data security by managing access controls, supporting audits, and improving governance processes. Leverage your expertise in data security tools to ensure compliance and...
5 days ago
Senior Cybersecurity Program Manager
$120K - $145K *
Lead a transformative cybersecurity initiative, collaborating across teams to execute and enhance enterprise security programs while shaping the organization's strategic roadmap for future improvement...
5 days ago
Technology Solutions Architect
$110K - $130K *
Join a collaborative technology architecture team to design scalable solutions, guide Agile development, and enhance application delivery while leveraging emerging technologies and cloud services...
5 days ago
$95K - $115K *
Champion the modernization of cloud-based analytics platforms by owning administration tasks, enhancing automation, and collaborating with technical leaders to ensure optimal performance and security...
5 days ago
Senior Data Security Analyst DLP Policy & Reporting (Proofpoint SME)
$110K - $130K *
Optimize data security initiatives by leading DLP policy development and enhancing detection accuracy. Collaborate with cross-functional teams to drive continuous improvement and strengthen enterprise...
5 days ago
Founding Senior Account Executive
$110K - $130K *
Drive Beam's growth by securing partnerships and expanding market presence. Lead the sales cycle for Beam Notes, engaging key sectors and refining strategies to enhance product-market fit in the US. Y...
5 days ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.