Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,696

Sort By: Relevance

$126K - $150K *

Champion growth strategies for net-new business, driving critical sales across cyber threat intelligence. Influence Fortune 1000 leaders in high-stakes environments while navigating complex sales cycl...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Engage with cross-functional teams to drive clinical trial success across regions. Leverage your expertise in project management and mentoring to ensure compliance, quality, and timely execution of st...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Grow strategic partnerships and drive revenue through collaboration with Independent Software Vendors (ISVs), ensuring alignment on business objectives and go-to-market strategies to enhance customer...

5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$130K - $160K *

Unlock your potential as a Senior Full Stack Software Engineer, leading impactful projects and shaping technology solutions. Collaborate across web applications, backend services, and cloud infrastruc...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Advance your career by overseeing geostructural projects, ensuring quality and safety while managing teams and resources across diverse construction environments. Collaborate with clients to develop i...

5 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$79K - $118K *

Champion patient care by collaborating with multidisciplinary teams to identify barriers, enhance engagement, and ensure seamless transitions. Leverage clinical expertise to optimize outcomes and deli...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $120K *

Drive revenue growth by optimizing systems and processes across Marketing, Sales, and Customer Success. Leverage data to enhance operational efficiency and establish HubSpot as a reliable source of tr...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Lead the charge in AI innovation within our Insurance portfolio, overseeing the full lifecycle of solutions from ideation to production. Shape strategy, manage multidisciplinary teams, and build new c...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$169K - $255K *

Shape the future of personalized consumer products by driving strategic partnerships and revenue growth. Lead business development efforts, cultivate relationships, and expand market reach to position...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Lead the development of innovative Campus Living properties, overseeing all phases from planning to operations. Drive financial success and quality standards while collaborating with teams across the...

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$79K - $139K *

Join a team that's dedicated to driving excellence in clinical trial contracts. As a Senior Site Contracts Manager, you'll negotiate and manage site budgets and agreements, collaborating with key stak...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Advance your career by leading medical writing projects in a regulatory environment. Collaborate with cross-functional teams to produce high-quality documents, ensuring compliance with industry standa...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$75K - $90K *

Accelerate your career by leading a dynamic restaurant team, driving sales growth, and ensuring exceptional customer service in a fast-paced environment. Enjoy competitive pay, robust benefits, and a...

5 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$75K - $90K *

Shape the future of dining by leading a dynamic team in a fast-paced environment. Drive sales growth and enhance customer experiences while enjoying competitive pay and robust benefits. Join us to mak...

5 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$110K - $130K *

Partner with us to drive transformative healthcare solutions by managing key accounts, fostering relationships, and ensuring measurable outcomes. Your expertise will enhance provider partnerships and...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Transform the future of brand engagement by leading impactful events that elevate visibility and strengthen customer relationships. Your expertise will drive marketing success through strategic planni...

5 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $150K *

Join a dynamic team as a compliance leader, overseeing U.S. Credit & Fraud Risk operations. Drive compliance initiatives, manage risk assessments, and collaborate with stakeholders to ensure adherence...

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $160K *

Transform your career by leading AI security architecture initiatives. Collaborate globally to design robust security frameworks for generative AI applications, ensuring compliance and operational res...

5 days ago

  •   5 - 7 years exp.  •   Staffing

$80K - $95K *

Drive compliance initiatives by managing environmental permits and programs, ensuring adherence to regulations while advising internal teams. Collaborate with management to enhance compliance procedur...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$95K - $115K *

Join a dynamic team to enhance data security by managing access controls, supporting audits, and improving governance processes. Leverage your expertise in data security tools to ensure compliance and...

5 days ago

  •   8 - 10 years exp.  •   Staffing

$120K - $145K *

Lead a transformative cybersecurity initiative, collaborating across teams to execute and enhance enterprise security programs while shaping the organization's strategic roadmap for future improvement...

5 days ago

  •   5 - 7 years exp.  •   Staffing

$110K - $130K *

Join a collaborative technology architecture team to design scalable solutions, guide Agile development, and enhance application delivery while leveraging emerging technologies and cloud services...

5 days ago

  •   5 - 7 years exp.  •   Staffing

$95K - $115K *

Champion the modernization of cloud-based analytics platforms by owning administration tasks, enhancing automation, and collaborating with technical leaders to ensure optimal performance and security...

5 days ago

  •   Less than 5 years exp.  •   Staffing

$110K - $130K *

Optimize data security initiatives by leading DLP policy development and enhancing detection accuracy. Collaborate with cross-functional teams to drive continuous improvement and strengthen enterprise...

5 days ago

  •   8 - 10 years exp.  •   Staffing

$110K - $130K *

Drive Beam's growth by securing partnerships and expanding market presence. Lead the sales cycle for Beam Notes, engaging key sectors and refining strategies to enhance product-market fit in the US. Y...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.