Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
$118K - $174K *
Drive strategic SAP project execution, ensuring cross-functional alignment and stakeholder engagement to optimize supply chain processes and achieve financial targets for large-scale ERP transformatio...
Reposted 1 week ago
$80K - $95K *
Drive impactful field marketing programs across the US, shaping the brand's presence and engaging prospects. Collaborate with sales to achieve pipeline goals, ensuring strategic execution of multiple...
Reposted 1 week ago
$100K - $120K *
Champion growth by managing diverse banking and retail accounts, leveraging your sales expertise to uncover opportunities and enhance customer solutions while collaborating across teams to drive resul...
1 week ago
$86K - $138K *
Drive independent assessments of deployment readiness across workstreams, ensuring quality and compliance. Collaborate with teams to produce readiness evaluations and present findings to leadership, e...
1 week ago
Director, Debt Capital Markets
$150K - $180K *
Join a dynamic team to shape the future of multifamily debt strategy, ensuring asset protection and optimizing financing across acquisitions and refinances while driving investor returns through disci...
1 week ago
Enterprise Account Manager (Strategic Renewals) - US
$120K - $150K *
Lead enterprise account renewals, driving retention and growth through strategic relationships with executives. Manage a significant book of business, ensuring customer satisfaction and navigating com...
1 week ago
Senior Director, Security Architect (USA - Remote)
$160K - $200K *
Reimagine security in cloud systems and software products. Drive architecture, governance, and hands-on implementation for robust security across AI, customer data, and development practices within a...
Reposted 1 week ago
Strategic Account Executive - Student-Florida
$105K - $110K *
Accelerate growth by leading complex sales strategies for education solutions. Engage with senior leaders to align priorities, drive partnerships, and deliver measurable outcomes while mentoring peers...
1 week ago
Contracts Administration, Senior Advisor
$112K - $179K *
Transform the contract management landscape by expertly overseeing diverse government contracts, optimizing processes, and guiding teams to success from proposal to closeout while fostering robust sta...
Reposted 1 week ago
Key Account Manager - San Francisco, California
$105K - $108K *
Elevate customer care by managing key accounts, driving performance, and fostering long-term relationships. Collaborate with cross-functional teams to deliver exceptional value, resolve issues, and im...
Reposted 1 week ago
Principal System Architect - MedDevice
$198K - $258K *
Lead the charge in defining and governing architectural strategies for a secure and scalable software ecosystem across device and digital platforms, influencing cross-functional teams and senior stake...
Reposted 1 week ago
$127K - $165K *
Unlock potential by leading regulatory strategies for innovative medical devices. Collaborate with teams to ensure compliance, execute FDA submissions, manage project timelines, and establish processe...
Reposted 1 week ago
Inventory & Cost Accounting Manager
$115K - $149K *
Champion efficient inventory and cost accounting processes, leading cross-functional collaborations. Drive accuracy in financial performance metrics while overseeing accounting operations in a dynamic...
Reposted 1 week ago
Senior Director, Regulatory CMC (remote)
$175K - $283K *
Champion regulatory excellence by leading CMC strategies for small molecule programs, ensuring compliance and driving successful submissions from early development through commercialization in a dynam...
1 week ago
Hospice Director of Clinical Services
$80K - $95K *
Join a dedicated team to oversee patient care and manage interdisciplinary services, ensuring quality and compliance in hospice settings. Lead with compassion and expertise to enhance the lives of pat...
Reposted 1 week ago
Clinical Development Associate
$92K - $120K *
Elevate clinical trial execution by supporting the development team in data review, safety tracking, and cross-functional collaboration to advance innovative clinical programs in ophthalmology...
1 week ago
Retirement Plan Specialist I (Financial Advisor/401k Participants) (Remote) (Kelsey Harris)
$70K - $95K *
Grow your career with a remote role assisting clients in navigating retirement solutions. Leverage your financial expertise to build relationships and provide guidance, all while enjoying a supportive...
1 week ago
Dir, EHR Revenue Cycle Applications
$141K - $211K *
Transform clinical and revenue-cycle operations by leading cross-functional teams to optimize technology solutions, ensuring efficient charge capture and financial reporting while enhancing patient sa...
1 week ago
Director, Market & Network Strategy
$163K - $214K *
Lead the charge in defining strategic market presence and network design. Drive investment decisions by analyzing demand, competition, and demographics to optimize facility configurations across multi...
1 week ago
Manager, Strategic Sourcing - Indirect (Technology)
$111K - $130K *
Grow a high-performing sourcing team while executing strategic initiatives across indirect spend categories. Collaborate cross-functionally to enhance supplier performance and drive operational effici...
1 week ago
Advisor, Bio Sample Operations - DMPK
$153K - $268K *
Empower your career by leading bio sample operations across clinical studies. Oversee end-to-end processes, ensuring compliance and quality while collaborating with cross-functional teams and external...
1 week ago
Senior Consultant - Outsourced Accounting Services (Non-Profit)
$73K - $127K *
Join our dynamic Outsourced Accounting Team to deliver tailored financial services, manage client accounts, and drive operational excellence. Collaborate with clients and team members to enhance their...
1 week ago
Senior Product Manager - Agents and Intelligence
$120K - $145K *
Transform the contract lifecycle by leading agent-driven workflows, leveraging data insights to enhance product value and customer satisfaction. Collaborate across teams to innovate and deliver user-c...
1 week ago
$150K - $180K *
Champion the growth of a self-directed engineering team, shaping processes, technical direction, and compliance in a fast-paced, regulated environment. Balance hands-on coding with leadership to drive...
1 week ago
Senior Account Executive - SMB SaaS
$70K - $115K *
Join a team that's transforming food safety compliance through innovative SaaS solutions. As a Senior Account Executive, you'll drive sales growth by managing the full sales cycle and building strong...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.