Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,063

Sort By: Relevance

$116K - $210K *

Elevate your career by providing expert systems administration and support across diverse environments. Engage in complex troubleshooting, security management, and infrastructure optimization while me...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Technical Services

$92K - $166K *

Empower seamless communication and collaboration as a UCC Engineer, focusing on Microsoft Teams. Leverage your expertise to support a mission-critical infrastructure, ensuring top-tier services for us...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Technical Services

$57K - $104K *

Elevate project quality by leading a team of permitting specialists in securing essential permits for electric utility infrastructure projects, ensuring compliance and timely approvals while fostering...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Technical Services

$73K - $132K *

Support commercial airport contracts by assisting project managers with requirements gathering, SOW generation, and project execution. Contribute to back-office operations and ensure timely invoicing...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Technical Services

$82K - $149K *

Join a team that's dedicated to enhancing Air Force logistics systems. Support critical operations by providing technical assistance and training for users globally, ensuring seamless logistics manage...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Technical Services

$87K - $157K *

Lead the charge in designing and reviewing structural components for substation and transmission projects, ensuring quality control and mentoring junior engineers while engaging with clients and suppo...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Technical Services

$185K - $344K *

Transform analytics modernization and productivity by leading strategy, governance, and process evolution. Collaborate with cross-functional teams to enhance workflows, drive AI adoption, and optimize...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$129K - $218K *

Unlock potential by driving strategic sales initiatives and operational improvements. Collaborate with leaders to enhance performance, resource allocation, and growth, transforming data into actionabl...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$125K - $130K *

Join a dynamic team as a Senior Cybersecurity Analyst, focusing on IT service recovery and business continuity. Collaborate with federal staff to develop strategies that ensure operational resilience...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$84K - $187K *

Join the AI Automation team to innovate and implement AI solutions that enhance efficiency and security. Collaborate with experts to build automations, connect systems, and experiment with cutting-edg...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$108K - $130K *

Lead the charge in enhancing site-of-care strategies by assessing, planning, and executing programs that optimize product administration across diverse healthcare settings, ensuring effective collabor...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$165K - $195K *

Lead the charge in developing and managing a robust Enterprise Data Warehouse on Databricks. Drive BI solutions, mentor a team, and ensure data quality while collaborating across departments to enhanc...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$186K - $280K *

Lead cross-functional initiatives and drive strategic program management to enhance operational efficiency and business growth. Collaborate with stakeholders to deliver impactful solutions and navigat...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$95K - $171K *

Transform client success by delivering tailored support and strategic insights, ensuring seamless onboarding and ongoing engagement with our innovative platform. Leverage your expertise in energy engi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$144K - $210K *

Drive compliance excellence by leading a team focused on identifying and addressing control gaps and violations across financial services, ensuring adherence to regulatory standards while enhancing su...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$263K - $395K *

Lead and influence AI-native technology initiatives, ensuring cohesive architectural standards across R&D. Deliver innovative solutions while mentoring engineering teams and shaping domain-wide practi...

RemoteRemote

Reposted today

  •   11 - 15 years exp.  •   Information Technology

$160K - $200K *

Lead the charge in building and guiding a US technical organization, ensuring battlefield-proven products meet US defense standards while fostering collaboration with global teams to enhance customer...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$140K - $200K *

Empower mission-critical federal systems by leading the design and automation of secure cloud platforms. Drive reliability, mentor engineers, and set technical direction in a collaborative environment...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Support senior leaders by providing agile administrative assistance, managing complex calendars, coordinating travel, and optimizing processes to enhance operational efficiency across the organization...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Elevate project success by managing multiple engagements, ensuring timely delivery, and fostering stakeholder relationships. Oversee a high-volume portfolio, driving efficiency and proactive risk mana...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$122K - $187K *

Unlock growth by driving strategic sales initiatives within assigned accounts. Collaborate with C-suite executives to deliver tailored technology solutions, ensuring exceptional customer experiences w...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$150K *

Shape the future of client success by leveraging insights and data to enhance program impact. Collaborate with leaders in law firms and professional services to drive engagement and talent development...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$180K - $240K *

Join us to build and operate secure infrastructure for federal and partner environments. This hands-on role focuses on Kubernetes, infrastructure as code, and production support, ensuring reliable dep...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$108K - $130K *

Lead and grow sales across the Western U.S. for architectural products. Drive revenue, build high-performing teams, and provide technical support to ensure successful project execution and customer sa...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Transform the banking landscape by driving sales success and building key relationships. Utilize your expertise to develop strategic solutions that meet client needs while achieving ambitious sales ta...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.