Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $111,580
DevSecOps Engineer / Security Specialist
$95K - $125K *
Elevate security practices by integrating SAST/DAST into CI/CD pipelines, hardening infrastructure with Ansible, and ensuring compliance with federal standards. Collaborate on vulnerability management...
1 week ago
$85K - $97K *
Accelerate progress at our team by developing and deploying full-stack solutions. Collaborate on REST APIs, enhance legacy applications, and ensure secure coding practices while delivering high-qualit...
1 week ago
$105K - $125K *
Join a team that's shaping the future of federal technology solutions. As a Technical Lead, you'll guide product development, oversee architecture, and mentor teams while ensuring compliance and secur...
1 week ago
$95K - $105K *
Drive cloud infrastructure excellence by managing environments, automating deployments, and ensuring security. Collaborate on cloud migrations and capacity planning while producing essential documenta...
1 week ago
$105K - $125K *
Engage as a Technical Lead, guiding product architecture and sprint execution while mentoring teams and ensuring compliance with VA standards. Drive technical strategy and oversee troubleshooting for...
1 week ago
$80K - $92K *
Empower teams to excel by facilitating Agile practices, coaching on SAFe 6.0, and managing sprint processes. Collaborate with stakeholders to ensure project success and drive continuous improvement in...
1 week ago
$75K - $90K *
Elevate patient care by preparing individuals for surgery through thorough assessments, education, and collaboration with surgical teams, ensuring a seamless and compassionate preoperative experience...
1 week ago
Senior Casualty Claims Specialist - Specialty Human Services
$101K - $146K *
Lead the charge in managing complex casualty claims, ensuring timely evaluations and settlements while collaborating with stakeholders to uphold coverage standards and compliance. Drive efficiency in...
1 week ago
$95K - $115K *
Join a team that's dedicated to providing exceptional pharmaceutical care and clinical services. You'll manage medication orders, supervise healthcare teams, and contribute to departmental goals while...
1 week ago
RN-Nurse Practitioner- BMG Oxford Endocrine Clinic
$90K - $110K *
Help us enhance patient care by diagnosing and managing health issues, collaborating with healthcare teams, and advocating for individuals and communities in diverse settings. Your expertise will driv...
1 week ago
Operations Lead, Strategic Growth Initiatives
$160K - $180K *
Join us as a strategic operator to drive high-priority growth initiatives, aligning cross-functional teams and transforming ideas into actionable plans while leveraging AI tools for enhanced efficienc...
1 week ago
Territory Sales Manager, Commercial position - AUSTIN, TX
$104K - $161K *
Champion growth by managing agency relationships and driving revenue in your territory. Develop and implement best practices to enhance sales performance while analyzing market trends to achieve profi...
1 week ago
Program Manager, Medical Education
$120K *
Partner with us to enhance product knowledge through comprehensive training programs, ensuring effective customer support and the growth of clinical expertise in the field sales organization. Be a cli...
Reposted 1 week ago
$70K - $90K *
Lead change and drive excellence in safety, quality, and customer experience. Collaborate with teams to enhance productivity and implement process improvements while mentoring a dedicated workforce in...
1 week ago
Regional Quality Manager, North East (Remote - Travel Required)
$116K - $146K *
Manage quality assurance for PV EPC projects, ensuring compliance with standards and regulations. Oversee inspections, audits, and training while collaborating with teams to enhance project quality an...
1 week ago
$110K - $130K *
Lead the charge in shaping market strategies and messaging for innovative traffic management solutions, collaborating across teams to drive customer engagement and adoption through compelling content...
1 week ago
Account Executive - East Coast
$100K - $120K *
Elevate traffic management solutions by driving revenue through strategic partnerships with government agencies. Cultivate relationships, identify opportunities, and execute sales strategies to achiev...
1 week ago
Pharmacy Manager - Full Time Flexible
$135K - $168K *
Drive exceptional patient care by leading a pharmacy team, promoting best practices, and ensuring compliance. Cultivate a culture of excellence while managing operations and enhancing patient experien...
1 week ago
$75K - $100K *
Join a team that's dedicated to enhancing information security and compliance operations. This mid-level role focuses on supporting security workflows, documentation, and IT service desk escalations...
1 week ago
Associate Director, Flight Operations (Internal Recruitment)
$95K - $115K *
Lead the charge in overseeing flight operations, ensuring safety and efficiency while advancing aerospace technologies through interdisciplinary research and collaboration with stakeholders...
1 week ago
Director, Field Intelligence Strategy & Governance
$185K - $344K *
Champion the evolution of field intelligence capabilities, driving strategic governance and analytics integration to enhance decision-making and execution support across the organization, ensuring ali...
1 week ago
Senior Trusts & Estates Tax Paralegal
$57K - $178K *
Champion the administration of estates and trusts, ensuring compliance and accuracy in tax filings while managing client relationships and case documentation. Leverage your expertise to deliver except...
1 week ago
EverHealth - Marketing Ops Systems and Analytics Specialist (Remote, US)
$90K - $110K *
Pioneer a unified marketing infrastructure by managing automation platforms, lead intelligence, and analytics. Collaborate with cross-functional teams to enhance data governance and optimize marketing...
1 week ago
Director, Global Drug Safety & Pharmacovigilance Operations
$150K - $180K *
Advance global drug safety initiatives by leading pharmacovigilance activities, ensuring compliance with regulations, and collaborating with cross-functional teams to enhance product safety and operat...
1 week ago
Senior Marketing Manager, Media (Oncology | LVL)
$143K - $194K *
Join a team that drives the execution of integrated media plans, ensuring compliance and operational excellence. Collaborate with cross-functional teams while enhancing brand strategies in healthcare...
Reposted 1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.