Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,580

Sort By: Relevance

$205K - $341K *

Unlock your potential by leading regulatory strategies for advertising and promotion. Collaborate with cross-functional teams to ensure compliance and drive successful commercialization initiatives in...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Engage in shaping a robust Environmental, Health, Safety, and Sustainability culture across 2,200+ retail locations. Collaborate with leadership to ensure compliance and drive operational excellence t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Engage with national accounts to drive sales and enhance customer satisfaction. Leverage local relationships and coordinate with internal teams to implement strategic growth plans in the fleet busines...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$188K - $230K *

Join a team that's driving innovation in data center materials. You'll manage strategic accounts, lead complex negotiations, and collaborate with global teams to enhance customer relationships and dri...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$110K - $120K *

Develop your career by providing technical support and consulting to ensure successful customer integration of complex bolting solutions. Collaborate with teams to meet customer needs through effectiv...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$108K - $162K *

Innovate in a strategic sales role, managing key accounts and driving revenue growth. Leverage technical expertise to build relationships and influence decision-making across the F5 solution portfolio...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$169K - $254K *

Lead and optimize the Solutions Engineering team in the Healthcare sector, focusing on technical sales and strategic planning. Drive team performance, manage recruitment, and ensure alignment with com...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $134K *

Join a team that's redefining financial planning by creating comprehensive tax strategies. Collaborate with advisors to analyze client data, deliver tailored tax plans, and stay updated on tax laws to...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$129K - $170K *

Champion compliance and legal support across privacy, SaaS contracts, and IP. Collaborate with teams on AI/ML, marketing, and product development while ensuring adherence to regulations and fostering...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$176K - $243K *

Accelerate progress at the forefront of cardiovascular innovation, leading a dynamic team to drive the adoption of advanced imaging solutions in the U.S. market, while fostering strategic partnerships...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Healthcare

$123K - $169K *

Elevate healthcare data integration by leading client engagements, optimizing EHR extracts, and providing strategic guidance. Utilize your SQL expertise to ensure data accuracy and foster strong clien...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$176K - $243K *

Unlock potential by driving the adoption of advanced electrophysiology solutions through strategic partnerships, enhancing customer engagement, and fostering relationships with key stakeholders to ens...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$176K - $243K *

Unlock potential by leading strategic initiatives in cardiovascular imaging, driving adoption of advanced technologies, and fostering partnerships to enhance patient care and clinical outcomes across...

RemoteRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Healthcare

$151K - $207K *

Unlock potential by driving strategic growth in healthcare sales, fostering executive relationships, and leading cross-functional teams to achieve commercial targets across Siemens Healthineers' Imagi...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$162K - $224K *

Transform healthcare operations by leveraging your expertise to drive efficiency and improve outcomes. Engage with clients to analyze needs, manage projects, and lead teams in delivering sustainable p...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Optimize your career as a Technical Project Manager, overseeing equipment procurement and supply chains. Collaborate with cross-functional teams, manage budgets, and negotiate contracts to ensure proj...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$94K - $130K *

Elevate product outcomes by collaborating with teams to prioritize and define user stories, ensuring alignment with business needs while maximizing value delivery and maintaining product quality throu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$98K - $163K *

Support audit remediation initiatives by coordinating with stakeholders, analyzing findings, and developing strategies to enhance audit readiness and internal controls, ensuring effective communicatio...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$74K - $124K *

Lead audit remediation initiatives by coordinating with stakeholders, analyzing findings, and developing strategies to enhance internal controls and audit readiness, ensuring successful outcomes for f...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$85K - $141K *

Analyze loan files to ensure compliance with SBA requirements, identifying risks and deficiencies. Collaborate with lenders to clarify documentation and prepare detailed reports, maintaining high stan...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$113K - $188K *

Transform client operations by delivering innovative solutions using Microsoft Power Platform. Lead implementations, automate processes, and ensure high-quality development while collaborating with st...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$98K - $163K *

Analyze and support federal clients in oversight and monitoring of grant programs, ensuring program integrity and accountability. Collaborate with stakeholders to assess risks, develop recommendations...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$113K - $188K *

Optimize security administration and reporting processes while collaborating with cross-functional teams to enhance data insights and compliance metrics. Drive effective use of Workday tools and ensur...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$206K - $343K *

Lead the charge in transforming healthcare operations by delivering innovative performance solutions. Drive profitable growth through strategic program management and client engagement, ensuring measu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$65K - $108K *

Champion the development and delivery of training materials and documentation, collaborating with stakeholders to ensure clarity and usability. Play a crucial role in enhancing learning and adoption t...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.