Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $111,580
$97K - $115K *
Drive strategic partnerships by managing key technology alliances, focusing on Microsoft. Collaborate across teams to identify growth opportunities, enhance partner engagement, and align initiatives w...
1 week ago
Software Engineer, Data & Analytics Platform
$120K - $145K *
Join a team that's building and scaling a data and analytics platform to enhance clinical AI performance. Collaborate with cross-functional teams to create actionable insights and drive improvements i...
1 week ago
Executive Director, Sales - West
$295K - $325K *
Drive strategic sales leadership across the Western US, translating brand vision into effective field execution. Build and sustain a high-performing team while collaborating cross-functionally to achi...
1 week ago
$112K - $179K *
Shape the future of data-driven insights by leveraging advanced machine learning techniques, collaborating with cross-functional teams, and communicating complex analyses to drive impactful business d...
Reposted 1 week ago
Director - Population Health & Well Being
$150K - $160K *
Lead the charge in executing population health strategies, ensuring high-quality consulting delivery and team performance across regions. Collaborate with leadership to drive impactful solutions and f...
1 week ago
$110K - $140K *
Transform infrastructure and deployment modernization efforts, serving as a technical cornerstone for multiple programs. Drive DevSecOps maturity and cloud adoption while ensuring secure, rapid delive...
1 week ago
$101K - $165K *
Transform co-marketing initiatives by executing strategic campaigns across diverse channels. Collaborate with partners and cross-functional teams to drive revenue growth, enhance brand awareness, and...
1 week ago
Associate / Analyst, Strategic Initiatives
$90K - $120K *
Advance strategic initiatives by collaborating across teams to launch innovative data tools and insurance programs. Drive project management efforts and contribute to executive presentations that shap...
1 week ago
$125K - $165K *
Join a dynamic team to oversee complex life application underwriting, ensuring risk selection aligns with financial goals. Drive process improvements and collaborate with stakeholders to enhance servi...
1 week ago
$85K - $100K *
Drive clinical excellence by partnering with agency leaders to assess, develop, and deliver tailored education programs for nursing staff, ensuring compliance and enhancing patient care across a netwo...
1 week ago
Behavioral Health Medical Director
$223K - $313K *
Shape the future of behavioral health care strategy and operations. Leverage your medical expertise to enhance quality, operational efficiency, and patient outcomes while navigating complex regulatory...
Reposted 1 week ago
Senior Applications Analyst - Billing
$123K - $207K *
Elevate enterprise systems by leading design and enhancements, ensuring reliability and usability. Collaborate with cross-functional teams to translate requirements into scalable solutions while drivi...
1 week ago
Senior Manager, AI Advisory and Open Source Program Office
$200K - $250K *
Unlock the potential of Open Source and AI governance by leading a multidisciplinary team to ensure compliance, drive best practices, and foster innovation across the enterprise, while collaborating w...
1 week ago
Senior Software Developer (Remote)
$108K - $130K *
Contribute to the development of innovative web applications using .Net, Angular, and SQL. Collaborate with a dynamic team to enhance existing systems and design new solutions, ensuring high-quality s...
1 week ago
$100K - $125K *
Champion data engineering excellence by designing and maintaining robust data pipelines and analytics solutions. Collaborate with stakeholders to enhance data quality and support enterprise-level data...
1 week ago
Senior Manager, People Operations
$120K - $130K *
Optimize the employee experience through innovative engagement strategies and precise HR operations. Be a key player in fostering a vibrant culture while ensuring operational excellence in onboarding...
Reposted 1 week ago
Territory Sales Manager, Commercial Trucking - IL
$104K - $161K *
Accelerate progress at driving agency relationships and revenue growth in the commercial trucking sector. Manage a diverse portfolio of accounts while implementing best practices to enhance sales perf...
1 week ago
Territory Sales Manager (Nebraska/Kansas)
$91K - $141K *
Empower agency growth by managing relationships and driving performance in Nebraska and Kansas. Lead strategic initiatives, deliver training, and ensure accountability to achieve sales goals while fos...
1 week ago
Solutions Architect, CTO Office - US
$150K - $180K *
Join us to tackle complex challenges as a strategic technical leader, influencing product direction and driving customer success. Your expertise will shape innovative solutions while engaging directly...
1 week ago
Senior Strategy & Decision Analyst
$120K - $145K *
Help us ensure high-quality decision-making by collaborating with leaders to frame strategies and analyze options, driving impactful decisions that align with organizational goals and values while fos...
1 week ago
Asset Manager, Global Realty Portfolio Management
$77K - $135K *
Join us to manage a diverse portfolio of 90-120 real estate assets, ensuring lease compliance and fostering strong landlord relationships while solving complex challenges across North America...
1 week ago
Deputy Director, Partnerships & Technical Integration
$196K - $210K *
Partner with us to shape the future of semiconductor workforce development by aligning industry needs with educational strategies, fostering partnerships, and leading initiatives that ensure technical...
Reposted 1 week ago
$98K - $134K *
Champion user-centered design as a Senior Product Designer, leading onboarding experiences that empower educators and learners. Collaborate across teams to create intuitive, impactful solutions that s...
1 week ago
Senior Product Designer, Developer Platform
$110K - $130K *
Transform developer experiences by designing intuitive growth-focused products. Collaborate with a dedicated team to enhance usability, streamline onboarding, and boost retention for impactful voice-d...
Reposted 1 week ago
GTM Strategy & Programs Manager
$135K - $169K *
Unlock your potential as you design and enhance go-to-market programs that drive sales productivity and revenue growth. Collaborate with cross-functional teams to translate strategy into actionable in...
Reposted 1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.