Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $111,580
$120K - $145K *
Lead the charge in optimizing pharmacy operations and services, ensuring compliance with regulations while enhancing patient care. Collaborate with teams to achieve strategic goals and improve drug th...
1 week ago
Self-Managed Business Development Manager- Central Region
$80K - $95K *
Lead the charge in expanding our commercial fleet market share by identifying and securing new business opportunities. Drive revenue growth through strategic prospecting, relationship building, and co...
1 week ago
$98K - $157K *
Transform product marketing for ERP platforms by crafting compelling messaging and content. Collaborate with cross-functional teams to drive go-to-market strategies and enhance customer engagement thr...
1 week ago
VP, Sales - Global Client Services
$120K - $140K *
Transform global client relationships by driving revenue growth and strategic account management. Collaborate with C-suite executives to connect workplace culture and employee experience to measurable...
1 week ago
$80K - $95K *
Elevate project outcomes by gathering requirements, improving processes, and providing training. Collaborate with clients and teams to customize solutions and ensure effective system administration wh...
1 week ago
Senior Pre-Sales System Engineer (Albany)
$156K - $234K *
Empower innovation in data storage by collaborating with sales teams to tailor solutions, drive customer success, and showcase technical expertise. Your role will bridge technology and business outcom...
1 week ago
$73K - $102K *
Join a dynamic consulting team as a Senior Developer, leveraging your SAP ABAP-Fiori expertise to design solutions, implement strategies, and drive client success in a rapidly evolving global landscap...
1 week ago
Alliance Marketing Manager, Artificial Intelligence
$126K - $273K *
Shape the future of alliance marketing by architecting innovative demand strategies with strategic tech partners, driving growth and impactful campaigns on a global scale, while collaborating across t...
Reposted 1 week ago
Manager, SEO Marketing (Virtual, US)
$85K - $95K *
Lead the digital strategy for consumer moving, driving SEO initiatives and managing a dynamic team. Shape innovative marketing approaches, optimize online presence, and enhance lead generation across...
1 week ago
Manager, Training & Workflow Optimization
$79K - $94K *
Optimize training and workflow processes by leading program development, mentoring trainers, and collaborating with stakeholders to enhance provider experiences and operational efficiency across Care...
1 week ago
Onboarding Engineer Technical Lead
$75K - $90K *
Elevate your career by leading a team of Onboarding Engineers, driving project efficiency, and enhancing processes. Foster collaboration and accountability while ensuring high-quality service delivery...
1 week ago
Security Analyst (Governance and Trust)
$89K - $105K *
Lead the charge in enhancing customer trust through security assurance and AI governance. This role focuses on maintaining accurate security documentation and optimizing AI agents to support governanc...
Reposted 1 week ago
Regional Sales Director (Remote)
$150K - $180K *
Lead and inspire a high-performing sales team to drive revenue growth and expand customer relationships in a competitive cybersecurity landscape, while developing strategic initiatives and fostering e...
1 week ago
Network Solutions Engineer - Fort Meade, MD
$108K - $130K *
Innovate solutions for network modernization by leading design, testing, and implementation efforts. Collaborate with stakeholders to ensure seamless integration of Ciena products, enhancing performan...
1 week ago
$80K - $95K *
Accelerate progress at a dynamic automotive SaaS company by owning the Mid-Market segment. Drive new business with multi-location auto repair groups, shaping strategies and building a scalable sales p...
1 week ago
National Quality Performance Manager (Remote)
$90K - $110K *
Advance quality performance initiatives by collaborating across departments to enhance healthcare outcomes, manage data analytics, and ensure compliance with regulatory standards, driving continuous i...
1 week ago
$69K - $119K *
Transform the landscape of clinical documentation by educating and mentoring teams, ensuring compliance, and enhancing documentation accuracy to optimize patient care and coding outcomes...
1 week ago
Captive Business Development Manager - River Oak Risk
$80K - $95K *
Drive new business generation in captive management solutions, focusing on multifamily risk and large P&C alternatives. Build relationships with brokers and multifamily owners while managing the full...
1 week ago
$82K - $132K *
Unlock potential in revenue cycle management by leading innovative solutions, optimizing processes, and collaborating across departments to enhance operational efficiency and maximize revenue impact...
1 week ago
Senior Software Engineer, Data Engineering Platform
$186K - $218K *
Innovate with a collaborative team as you build scalable blockchain infrastructure, design APIs, and streamline complex data processes. Your contributions will enhance system reliability and performan...
Reposted 1 week ago
$106K - $167K *
Pioneer growth as a Senior Field Sales Executive, driving success in the Eastern US. Manage key accounts, develop strategies, and build relationships to enhance customer satisfaction and achieve sales...
1 week ago
Senior Power BI Technical Consultant
$110K - $130K *
Unlock potential by designing and deploying Power BI solutions that transform data into actionable insights. Collaborate with stakeholders to create scalable models and enhance reporting capabilities...
1 week ago
Lead Platform Engineer - Infrastructure & Backend
$150K - $185K *
Take ownership of our cloud and backend infrastructure, driving technical direction and improvements. Lead a team to ensure reliability and scalability of systems supporting our games and analytics, w...
1 week ago
Sr. Revenue Enablement Manager, Groups
$115K - $160K *
Drive your career forward by enabling the Groups team to excel in revenue generation through innovative training, AI-driven tools, and strategic partnerships, ensuring consistent performance and growt...
1 week ago
Staff Software Engineer, Search Backend
$200K - $250K *
Elevate the search experience by designing and evolving a robust backend system that powers millions of searches. Collaborate across teams to enhance scalability, reliability, and maintainability whil...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.