Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $110,967

Sort By: Relevance

$80K - $95K *

Lead the charge in driving customer success for mid-market accounts, ensuring adoption and renewals while identifying growth opportunities. Collaborate cross-functionally to enhance customer experienc...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Champion the evolution of organic search strategies across enterprise software brands. Lead initiatives in technical SEO, content optimization, and AI-driven search, driving visibility and revenue whi...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $140K *

Join a dynamic team to drive business growth by identifying and cultivating strategic partnerships. Leverage market insights to develop tailored solutions that meet mission needs and enhance client re...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Lead the strategic growth of technical integration services, overseeing specialized consultants and ensuring seamless, high-quality delivery of complex integrations while shaping the technical service...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$165K - $200K *

Transform federal programs by leading owner's representative services, ensuring effective project delivery from inception to closeout. Leverage commercial real estate expertise to advocate for owners...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$93K - $146K *

Champion sustainable design by leading complex mechanical systems for high-performance buildings, ensuring compliance with advanced standards and certifications while driving innovative engineering so...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Technical Services

$80K - $95K *

Deliver comprehensive psychological assessments and evidence-based interventions, guiding treatment plans for complex cases. Collaborate with interdisciplinary teams and supervise trainees while enhan...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Lead the charge in managing district field service operations, driving profitability, and enhancing customer satisfaction through effective team leadership and strategic coordination across multiple r...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $219K *

Optimize medical sponsorship strategies and operations by collaborating with stakeholders, managing budgets, and ensuring timely execution of congress activities while enhancing process efficiency and...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Drive global access strategies for an innovative rare disease treatment, collaborating across teams to enhance payer insights and develop impactful materials. Lead initiatives that shape market entry...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$65K - $150K *

Explore the forefront of AI technology, tackling complex challenges and enhancing intelligent systems. Collaborate with engineers to troubleshoot and improve performance across various platforms, shap...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$96K - $125K *

Join a team that's focused on enhancing delivery across cross-functional initiatives, ensuring timely execution and risk management. Collaborate with diverse teams to drive improvements and elevate cu...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$207K - $250K *

Unlock your potential as you lead engineering teams in building innovative platforms and AI experiences. Collaborate across departments to drive technical direction and elevate team performance while...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Business Services

$100K - $120K *

Drive growth by leading a high-performing sales team focused on early-stage companies. Collaborate with leadership to refine strategies, enhance sales processes, and foster a supportive culture, ensur...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Join a team that's dedicated to ensuring compliance and excellence in clinical trials. Collaborate with cross-functional teams and site personnel to manage monitoring activities, uphold regulatory sta...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Join a team that's redefining cybersecurity by leveraging AI to enhance defense strategies. Engage with customers across the Americas, translating complex concepts into actionable insights while drivi...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Unlock potential by driving growth for a leading payment solution, collaborating with cross-functional teams to enhance customer engagement and conversion. This role demands agility in a fast-paced en...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Transform business development by leveraging technical expertise to build customer relationships, identify opportunities, and deliver tailored solutions. Join a dynamic team focused on driving sales g...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Technical Services

$120K - $140K *

Transform the renewable energy landscape by driving solar module sales in the Northwest. Leverage your expertise to build relationships, uncover opportunities, and achieve sales targets while managing...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$138K - $165K *

Shape the future of consumer applications by leading machine learning and Generative AI initiatives. Build robust data pipelines, develop and deploy models, and drive business impact through experimen...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Partner with us to tackle complex operational challenges, driving impactful initiatives across our portfolio. This role offers hands-on experience and growth opportunities, ideal for future leaders ea...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $145K *

Engage with cross-functional teams to drive AI security product marketing initiatives, focusing on buyer insights, competitive analysis, and effective sales enablement. Collaborate on launches and con...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $105K *

Engage with global customers as a trusted advisor, solving complex workflow challenges through innovative color management solutions and professional services, while collaborating with sales teams to...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$66K - $102K *

Unlock your potential as a Senior SAP FICO Consultant, driving impactful solutions and collaborating with teams to enhance financial processes. Leverage your expertise to deliver value in a dynamic co...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $104K *

Optimize ETL processes by designing and maintaining robust data integration solutions. Collaborate with cross-functional teams to ensure data accuracy and performance, while mentoring junior developer...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.