Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,896

Sort By: Relevance

$265K - $295K *

Engage communities as a trusted partner, fostering relationships and collaboration throughout the lifecycle of infrastructure projects. Shape local engagement strategies, ensuring transparency and mut...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Shape pharmaceutical care in a community practice setting, ensuring safe and effective drug therapy. Collaborate with healthcare teams, oversee pharmacy technicians, and support clinical initiatives w...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$170K - $220K *

Champion transportation optimization by leading strategic initiatives that enhance service, cost efficiency, and network performance across global operations. Drive innovation in operating models and...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$150K - $170K *

Unlock potential by leading pricing operations and contracting strategies, ensuring compliance and revenue optimization across diverse healthcare products. Collaborate with cross-functional teams to e...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $170K *

Elevate your career by leading pricing operations and contracting initiatives. Collaborate with cross-functional teams to optimize pricing strategies, ensure compliance, and drive revenue growth acros...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$145K - $185K *

Join a dynamic team as a Senior Marketing Analytics Manager, driving marketing performance measurement and insights. Collaborate cross-functionally to build impactful reporting and attribution models...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$155K - $170K *

Lead the charge in shaping enterprise business solutions through hands-on architecture and delivery in Microsoft Dynamics 365 Finance & Operations, focusing on integration, process optimization, and o...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Staffing

$106K *

Join us in overseeing the Maintenance of Way Department, ensuring efficient operations and safety compliance while managing a skilled team to meet service goals and budgetary constraints...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Transportation

$84K *

Empower seniors by delivering personalized care in their homes. Collaborate with a dedicated team to enhance quality of life through comprehensive assessments and meticulous documentation, ensuring ex...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$185K - $230K *

Advance patient access and reimbursement strategies in rare diseases. Collaborate cross-functionally to educate providers and support patients, ensuring compliance and effective navigation of complex...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$191K - $253K *

Join a dynamic team as a Senior FPGA Verification Engineer, driving the design and testing of cutting-edge imaging systems. Collaborate with experts to develop prototypes and enhance verification proc...

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$68K - $109K *

Transform installed base management by leading operations and ensuring data integrity. Collaborate cross-functionally to optimize asset management processes and provide guidance as the primary platfor...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$180K - $220K *

Elevate your veterinary career by delivering exceptional emergency care in a supportive environment. Join a dedicated team focused on high-quality patient outcomes while enjoying a flexible schedule a...

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$75K - $94K *

Drive data solutions by collaborating with cross-functional teams to develop and maintain backend integrations within Azure Gov Cloud, ensuring data integrity and security for government clients...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $185K *

Lead cross-functional teams to drive excellence in software development for a SaaS platform, ensuring timely delivery and high-quality outcomes while fostering a collaborative engineering culture. Inn...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$103K - $173K *

Transform project execution by managing end-to-end service operations, ensuring safety, quality, and cost-effectiveness while serving as the primary customer interface and leading a team to meet perfo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$150K - $180K *

Unlock potential by leading the vision and strategy for billing and marketplaces. Drive innovation in usage metering, invoicing, and payment systems while collaborating with cross-functional teams to...

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Grow your career with a strategic role driving account management, fostering executive relationships, and leading complex deals to secure growth in a dynamic cybersecurity environment. Shape multi-yea...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Join us to drive strategic growth by managing key accounts, building executive relationships, and leading complex deals. Shape multi-year strategies and collaborate with a virtual team to deliver impa...

Waltham, MARemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$175K - $257K *

Transform software quality assurance by leading a high-performing team, establishing modern verification standards, and driving compliance across complex systems and automation platforms to ensure exc...

1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$160K - $200K *

Drive scientific strategy and lead therapeutic programs in neurobiology, overseeing target validation to preclinical proof-of-concept. Collaborate with teams to identify novel targets and foster partn...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$225K - $324K *

Accelerate growth by leading global enablement initiatives that empower sellers, engineers, and partners. Drive strategic programs, enhance skills, and ensure readiness for a multi-product platform in...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$155K - $194K *

Elevate program management by ensuring effective operations for clinical development teams. Collaborate with leaders to streamline processes, manage timelines, and foster a cohesive team environment...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$144K - $170K *

Empower enterprise security sales as a relentless hunter, leveraging diverse demand gen strategies. Drive revenue growth by developing prospects, closing new deals, and expanding customer relationship...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Join a team that's driving strategic partnerships in Retail and Hospitality. Manage relationships with technology providers, identify growth opportunities, and develop compelling business cases to enh...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.