Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$162K - $243K *

Join a team that's dedicated to advancing clinical trials through strategic oversight and collaboration. Lead project management efforts globally, ensuring quality, cost, and timeline objectives are m...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$91K - $121K *

Shape the future of project management by leading enterprise initiatives, establishing standards, and ensuring effective execution of organizational priorities in a remote setting...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$155K - $259K *

Drive your career forward by leading project delivery across teams, ensuring alignment with product priorities and engineering capacity. Foster collaboration, manage risks, and enhance performance met...

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$105K - $120K *

Elevate project management excellence by leading a dynamic team, ensuring high-quality execution across flagship accounts, and driving operational efficiency through strategic oversight and collaborat...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $230K *

Take ownership of a dynamic project management team, driving strategic initiatives and delivering exceptional client service across a diverse portfolio of complex projects while fostering strong relat...

Yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$90K - $100K *

Transform software delivery by managing cross-functional teams, aligning sprints, and optimizing project timelines. Drive clarity in processes and foster collaboration to ensure successful product exe...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $100K *

Lead the charge in managing software delivery across teams to enhance our healthcare marketing platform. Ensure timely project milestones, adapt Agile processes, and drive effective communication whil...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$175K - $225K *

Drive strategic program management excellence across a diverse client portfolio, ensuring alignment, governance, and operational execution. Lead a team of professionals to enhance client engagement an...

Yesterday

  •   8 - 10 years exp.  •   Business Services

$175K - $225K *

Lead the charge in shaping strategic program management across a diverse client portfolio. Oversee a team of professionals to ensure excellence in execution, governance, and client engagement while dr...

Boston, MARemote

Yesterday

  •   8 - 10 years exp.  •   Business Services

$162K - $243K *

Shape the future of clinical research by leading cross-functional teams to optimize project delivery, ensuring quality and compliance while managing resources and budgets effectively across global cli...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$130K - $150K *

Empower teams by driving technical project execution, ensuring deliverables are met through rigorous planning, cross-functional collaboration, and proactive risk management. Your expertise will enhanc...

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Champion the successful delivery of customer projects through all phases, ensuring alignment with business goals by coordinating teams and resources while managing risks and transacting key communicat...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$170K - $303K *

Drive innovative product development programs through effective leadership and strategic management, overseeing all phases from conception to market launch while ensuring cross-functional collaboratio...

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Optimize the implementation of Epic Clinical EHR for State Healthcare Facilities, leading project planning, stakeholder engagement, and team coordination while ensuring quality, scope, and communicati...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$104K - $130K *

Join a team that's driving project success in mission-critical environments. As a Project Manager, you'll oversee design and construction phases, manage stakeholder relations, and ensure project profi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$85K - $130K *

Grow and lead complex multidisciplinary projects from initiation to completion. Collaborate with diverse teams and clients to deliver high-quality results while managing budgets, schedules, and relati...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$201K - $251K *

Join us to lead cross-functional project management in a dynamic biotech environment. Drive global commercialization initiatives, ensuring alignment and execution across teams while enhancing operatio...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the charge in optimizing project management processes for a VHA client team. Utilize your expertise to enhance strategic planning, decision-making, and execution while collaborating with senior s...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$131K - $158K *

Oversee multiple facility infrastructure projects, ensuring compliance with regulations and safety standards. Collaborate with teams to manage budgets, timelines, and resources while delivering high-q...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $172K *

Drive strategic leadership for project and resource management, ensuring timely delivery and optimal resource utilization. Collaborate with cross-functional teams to enhance customer experience and fi...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$100K - $120K *

Champion the redesign and implementation of employee onboarding processes, leading cross-functional teams through the project lifecycle while ensuring alignment and continuous improvement in a complex...

2 weeks ago

  •   Less than 5 years exp.  •   Staffing

$100K - $120K *

Lead the charge in transforming employee onboarding processes through Workday, managing the entire project lifecycle from design to implementation. Collaborate with cross-functional teams to ensure al...

Boston, MARemote

2 weeks ago

  •   Less than 5 years exp.  •   Staffing

$95K - $115K *

Lead the charge in managing multiple construction projects, ensuring timely delivery and budget adherence. Guide teams through the entire construction process, from preconstruction planning to project...

1 month ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$141K - $211K *

Champion cross-functional technology initiatives by managing project roadmaps, ensuring timely delivery, and aligning stakeholders. Drive accountability and mitigate risks to support successful projec...

Yesterday

  •   5 - 7 years exp.  •   Legal & Accounting

$110K - $130K *

Join a dynamic team to lead and manage multiple large-scale projects, collaborating with diverse stakeholders to deliver innovative software solutions in a global legal environment. Drive project succ...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.