Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,902

Sort By: Relevance

$60K - $110K *

Advance project execution by leading remodels and new store initiatives. Collaborate with teams to ensure timely delivery, budget adherence, and quality standards while developing associates and manag...

6 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$132K - $311K *

Transform enterprise performance by leading strategic initiatives and driving cost reduction. Collaborate with senior stakeholders to shape solutions that enhance productivity and deliver measurable v...

6 days ago

  •   5 - 7 years exp.  •   Business Services

$178K - $257K *

Shape the future of IBD treatment by leading global HCP marketing strategies, driving innovative campaigns, and engaging key stakeholders to enhance awareness and adoption of groundbreaking therapies...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$178K - $257K *

Join a dynamic team as a lead biostatistician, guiding vital vaccine projects while ensuring scientific integrity and collaboration across global teams. Drive innovation and operational efficiency in...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K *

Play a key role in delivering effective Occupational Therapy services by evaluating patients, recommending treatment plans, and supervising support staff to ensure optimal care and outcomes in a colla...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Shape the future of clinical research by managing trials from startup to closeout. Collaborate cross-functionally, oversee vendors, and ensure compliance while driving operational excellence in a dyna...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K *

Join a team that's dedicated to delivering exceptional occupational therapy services. Evaluate and treat patients effectively while supervising support staff and ensuring compliance with regulatory st...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $110K *

Lead the charge in defining strategic visions and multi-service roadmaps for medium to large accounts, integrating marketing with cross-functional business strategies to drive growth and client satisf...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$101K - $165K *

Develop and execute integrated marketing programs to drive merchant acquisition and activation through platforms and ISVs, leveraging data to optimize performance and enhance partner relationships for...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $105K *

Transform virtual resettlement services by leading a national portfolio that enhances access for refugees. Oversee strategy, implementation, and compliance while fostering partnerships and innovative...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Analyze market needs and drive customer engagement through strategic lifecycle campaigns. Collaborate across teams to position the platform effectively, ensuring consistent messaging and measurable gr...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$82K *

Lead the charge in coordinating impactful clinical research studies focused on upper respiratory infections. Engage participants, manage operations, ensure compliance, and collaborate with partners to...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$70K - $103K *

Elevate your healthcare leadership career by overseeing cardiac surgery operations, enhancing team performance, and optimizing workflows to ensure exceptional patient care in a dynamic, collaborative...

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$83K - $99K *

Execute patient care duties by operating radiographic equipment to produce diagnostic imaging. Collaborate with a multi-disciplinary team while ensuring safety protocols and patient understanding thro...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$118K - $172K *

Manage and oversee radiation therapy operations, ensuring high-quality patient care and staff performance. Collaborate with cross-functional teams to optimize workflows and maintain clinical excellenc...

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$79K - $115K *

Optimize program execution by leading strategic initiatives, enhancing operations, and fostering team collaboration to achieve organizational goals efficiently and effectively...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $111K *

Join a team that's shaping the future of energy through advanced modeling and automation. This role focuses on Synergi Electric modeling, special studies, and MATLAB-based solutions, supporting critic...

6 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$100K - $111K *

Shape the future of energy by leading advanced modeling and forecasting initiatives. Collaborate across teams to deliver rigorous planning studies, enhance automation, and support strategic distributi...

6 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$100K - $120K *

Transform customer experiences by leading end-to-end implementations. Drive project timelines, stakeholder alignment, and ensure successful platform adoption to meet defined goals. Your leadership wil...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$130K - $155K *

Join a dynamic team to shape the future of advanced processing solutions for mission-critical applications in defense and aerospace. Drive product lifecycles, collaborate with cross-functional teams...

6 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$80K - $95K *

Transform integration testing by collaborating with leads to ensure high-quality, validated solutions. Drive operational testing and develop strategies that meet clinical standards, enhancing client s...

Wellesley, MARemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$88K - $107K *

Contribute to efficient accounting operations by managing journal entries, reconciliations, and compliance with accounting standards. Collaborate with teams to enhance financial reporting accuracy and...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Drive quality assurance in integration solutions, collaborating with leads to validate and test applications. Ensure compliance with SOPs while developing tailored validation plans and executing tests...

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$113K - $210K *

Champion the future of technology audit by leading a high-performing team to deliver innovative, risk-based audit services across North America, enhancing operational efficiency and ensuring complianc...

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Champion revenue growth by managing ISV channel partners, driving strategies, and optimizing performance. Build strong relationships, analyze data, and identify new opportunities to enhance profitabil...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.