Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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1,000+

Jobs in Kentucky

Average Salary in USD

Average Salary: $108,106

Sort By: Relevance

$164K - $189K *

Transform cloud environments by architecting and supporting multi-cloud solutions. Leverage your expertise in AWS and identity management to ensure seamless service delivery and customer satisfaction...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$118K - $174K *

Lead the charge in delivering large-scale SAP transformation programs, ensuring strategic alignment and effective stakeholder collaboration while managing risks and optimizing resources for successful...

United StatesRemote

2 weeks ago

  •   15+ years exp.  •   Information Technology

$115K - $194K *

Empower our Solutions Architects by enhancing operational tools and workflows. Drive efficiency and effectiveness in customer engagement processes, ensuring data quality and reporting standards are me...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $145K *

Champion innovative solutions as a Senior Business Analyst, driving requirements gathering and Agile processes to enhance custom applications for DHS. Collaborate with teams to streamline operations a...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$204K - $290K *

Empower the future of fraud prevention by leading cross-functional projects, designing innovative systems, and mentoring engineers. Drive growth while safeguarding users through data-driven insights a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $190K *

Empower project success by managing sales opportunities, creating piping layouts, and fostering strong customer relationships. Utilize your engineering expertise to navigate complex situations and del...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Lead the charge in optimizing business operations by collaborating across departments, managing cross-functional projects, and enhancing performance. Drive strategic initiatives and support the operat...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$110K - $130K *

Lead the charge in shaping product operations for a growing team. Design and implement systems that enhance efficiency, visibility, and collaboration, ensuring the product team thrives in a dynamic, e...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Transform product security by leading strategy, conducting threat modeling, and collaborating across teams to ensure secure design and compliance. Drive innovation in security practices while mentorin...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Champion long-term sales strategies by managing the full sales cycle, engaging stakeholders, and driving revenue growth within enterprise accounts while navigating complex negotiations and fostering s...

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Drive the evolution of our product operations by designing and implementing systems that enhance team efficiency, visibility, and collaboration. You'll empower product managers and shape the future of...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $138K *

Transform project execution by leading cross-functional teams in energy storage preconstruction. Oversee budgeting, scheduling, and documentation to ensure project success while fostering collaboratio...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$110K - $140K *

Elevate our healthcare growth strategy by managing pipeline generation, leveraging AI tools, and driving marketing initiatives. This role demands autonomy and innovation to shape business operations a...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$135K - $185K *

Unlock potential by driving enterprise sales growth through strategic account management, leveraging industry expertise, and building strong client relationships to exceed revenue targets and enhance...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $130K *

Drive the transformation of customer data into automated reporting and AI tools, enhancing customer health tracking and executive visibility. Collaborate across teams to streamline workflows and ensur...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Take ownership of the product strategy for AI applications, defining the roadmap and driving profitability. Collaborate cross-functionally to build and launch innovative products that enhance user exp...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$94K - $148K *

Shape the future of healthcare by driving customer experience insights that influence product and business strategies. Collaborate with cross-functional teams to conduct impactful research and advocat...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Engage in early-stage drug discovery by triaging research requests, managing CRO partnerships, and ensuring seamless execution of outsourced projects. Leverage scientific expertise and Mandarin fluenc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$181K - $301K *

Elevate our cyber defense capabilities by architecting advanced detection and response systems. Lead cross-functional initiatives, influence technical strategy, and enhance security measures to protec...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$100K - $120K *

Unlock potential by joining a dynamic team of veterinary professionals, providing high-quality emergency care and surgical interventions in a state-of-the-art facility, while collaborating with skille...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $100K *

Optimize revenue growth by driving GTM excellence and data-driven insights. Collaborate across Sales, Customer Success, and Finance to establish streamlined operations and enhance performance reportin...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$250K - $275K *

Transform the future of drug development by leading Analytical Development for small molecules and oligonucleotides. Drive scientific strategy, build a high-performing team, and ensure regulatory read...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$155K - $175K *

Serve as a key scientific partner in the field, driving prelaunch and launch strategies through trusted relationships, high-quality exchanges, and actionable insights to enhance product adoption and c...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$215K - $240K *

Shape the future of commercial operations by leading strategy, workflows, and data integration. Collaborate with senior leaders to enhance brand performance and drive operational excellence across cro...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $250K *

Engage with diverse stakeholders to drive sales growth in FWA, M2M, and IoT solutions. Develop new customer relationships while enhancing existing accounts, leveraging a robust channel ecosystem to ma...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.