Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$170K - $215K *

Join our innovative R&D team to lead analytical development for therapeutics in microgravity. Drive projects from conception to regulatory filing, while mentoring junior scientists, shaping product st...

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$111K - $120K *

Lead the charge in R&D for cutting-edge filtration technologies across diverse sectors, driving innovation in microelectronics and aerospace. Collaborate with cross-functional teams to enhance product...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Optimize E&L study execution and compliance through strategic leadership, ensuring high-quality data for regulatory submissions while mentoring teams and aligning goals with product development initia...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Lead the charge in advancing bioseparation analytical methods for large molecules. Drive innovation in biologics characterization, supporting drug development through hands-on execution and scientific...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Elevate your scientific career by leading innovative LCMS initiatives, defining analytical strategies, and delivering impactful results within the pharmaceutical industry while mentoring emerging scie...

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Unlock potential by leveraging deep scientific expertise and technical skills to partner with customers, ensuring the delivery of complex SaaS solutions while driving integration and data architecture...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Innovate your career by providing analytical support for pharmaceutical development, conducting method validation, and leading studies while ensuring compliance and collaboration within a dynamic team...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $120K *

Lead innovative hair care formulation development from concept to market, utilizing advanced chemistry and collaboration across teams to overcome formulation challenges, ensure product safety, and dri...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $224K *

Join a team that drives Drug Substance development, overcoming complex challenges in monoclonal antibody manufacturing and scaling processes, while ensuring compliance and quality at every stage of pr...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$122K - $156K *

Join the forefront of scientific inquiry by leading impactful exposure science projects. Collaborate with diverse teams to mitigate health risks while enhancing your expertise through mentorship and c...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $122K *

Drive advancements in RNAi target discovery by independently executing molecular biology assays, managing cell cultures, and analyzing data to support neuroscience projects in a collaborative lab envi...

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $179K *

Unlock your potential as an analytical development lead, guiding innovative monoclonal antibody projects from preclinical to commercialization, ensuring compliance and delivering analytical excellence...

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$135K - $150K *

Lead the charge in expanding preclinical studies in toxicology for cell and gene therapy programs. Ensure safety evaluations, provide expert guidance, and drive scientific innovation while mentoring j...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Take ownership of high throughput biology capabilities, designing and executing robust biochemical and cell-based assays while collaborating across teams to drive small molecule discovery and deliver...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$114K - $228K *

Drive clinical innovation by leading trial design and execution in collaboration with internal and external stakeholders to support regulatory submissions and strategic business goals within the vascu...

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$120K - $150K *

Lead the charge in advancing oncology through in vitro discovery biology, collaborating across programs to validate targets and drive innovative therapeutic solutions...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Join a team that's pioneering in vitro discovery biology to advance oncology programs, conducting target validation and developing innovative therapies across various modalities while driving research...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$131K - $161K *

Lead and oversee pre-market approval projects in food safety; provide strategic regulatory guidance, manage multi-disciplinary projects, and mentor team members in this dynamic role focused on health...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$144K - $269K *

Lead advances in peptide therapeutic discovery by developing innovative computational methods and machine learning models to optimize peptide properties and streamline workflows for drug discovery...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$142K - $256K *

Join a team that's pioneering microbial production strategies for recombinant enzymes and plasmids, driving high-performance screening workflows, and ensuring robust process development to support inn...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$124K - $207K *

Drive early-stage drug design and delivery as a Senior Principal Scientist, providing leadership and scientific strategy across multi-disciplinary teams to optimize molecular and drug formulation stra...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $187K *

Drive biomarker strategy for clinical studies, ensuring data quality and compliance. Collaborate across functions and external partners to enhance clinical outcomes in solid organ transplant research...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Unlock potential by joining a dynamic R&D team as a Senior Scientist in DMPK. Lead drug development through strategic planning, research execution, and collaboration to drive therapies from discovery...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $222K *

Lead the charge in developing advanced AI/ML models for predictive toxicity assessments. Collaborate with cross-functional teams to integrate multi-modal biological data, driving insights that improve...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Champion advanced sterile manufacturing processes, driving optimization and compliance in liquid and lyophilized parenteral operations while collaborating cross-functionally to enhance performance and...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.