Explore $100K+ Jobs in Illinois

Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.

Career Opportunities Across Illinois

Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.

Find a Role That Fits Your Experience

Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.

Advance Your Career in Illinois

Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.

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1,000+

Jobs in Illinois

Average Salary in USD

Average Salary: $117,822

Sort By: Relevance

$140K - $165K *

Drive innovative fraud risk management solutions by leveraging advanced machine learning and data analytics. Collaborate with stakeholders to enhance model development and mentor junior data scientist...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Join us to lead construction projects, ensuring quality and safety while managing subcontractors and maintaining client relationships. Collaborate closely with project managers to deliver successful o...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$200K - $250K *

Join a dynamic team as a senior leader to enhance transmission engineering services, oversee project delivery, and strengthen client relationships while driving innovation and growth in the energy sec...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$80K - $95K *

Elevate your career by supervising a dynamic Blood Bank laboratory team, ensuring compliance, training staff, and enhancing operational efficiency while collaborating with pathologists to deliver accu...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$190K - $210K *

Lead the charge in strategic AI initiatives, coordinating cross-functional teams to drive program success. Utilize your program management expertise to align priorities, manage risks, and enhance AI c...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$95K - $115K *

Drive client success by serving as the primary technical liaison for strategic partners, ensuring seamless data integrations and ongoing support while collaborating with cross-functional teams to solv...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$110K - $130K *

Champion strategic initiatives as a Business Systems Analyst Lead, driving impactful solutions through collaboration with stakeholders and technical teams. Leverage analytical skills and technical exp...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Advance your career by leading a global team in revenue recognition and technical accounting. Drive policy development, ensure compliance, and partner with cross-functional teams to optimize financial...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$170K - $205K *

Pioneer legal strategies in privacy, AI, IP, and consumer litigation, collaborating cross-functionally to support governance programs, manage IP strategy, and oversee litigation matters, ensuring comp...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$250K - $290K *

Champion growth by developing best-in-class business practices, leading a high-performing new business team, managing pipeline opportunities, and fostering strategic partnerships with leadership to dr...

RemoteRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$250K - $290K *

Join a team that's driving innovative business development in healthcare advertising. Lead the new business function, develop high-performing teams, and partner with leadership to enhance growth and c...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$105K - $130K *

Join a dynamic team to lead multiple client engagements, driving innovative solutions and strategic direction. Foster cross-functional collaboration in a fast-paced environment with a focus on deliver...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$105K - $130K *

Partner with us to lead client engagements, drive strategic solutions, and enhance healthcare outcomes through innovative teamwork and market insights. Become a trusted advisor and empower teams to ex...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Champion effective publication strategies and lead scientific communication initiatives, acting as a strategic partner to clients and teams. Navigate complex medical affairs content to drive impactful...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $170K *

Join a dynamic team to lead client relationships, drive strategic initiatives, and foster collaboration across departments. This role emphasizes innovation and adaptability in a fast-paced healthcare...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$70K - $100K *

Lead the charge in optimizing global partner program operations, enhancing partner experiences, and driving continuous improvement across regions. Collaborate with teams to ensure seamless execution a...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$170K - $190K *

Join a team that's transforming behavioral health care delivery through innovative leadership and strategic oversight. Drive operational excellence and improve client outcomes across multiple sites wh...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $225K *

Shape the future of our national sales strategy by leading a high-impact team focused on driving revenue growth within the security integration sector. Your leadership will optimize our distributed sa...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Staffing

$175K - $230K *

Empower healthcare innovation by leading a team of Field Clinical Specialists. Drive the successful launch of the Globe Pulsed Field System through training, support, and relationship-building with he...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$112K - $135K *

Drive the transition to fully automated cloud infrastructure using AWS CDK, enhancing collaboration between software engineering and cloud operations to ensure efficient, secure, and scalable service...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $175K *

Shape the future of client partnerships by driving strategic growth and success for large enterprise organizations. Collaborate with cross-functional teams to deliver exceptional value and measurable...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$130K - $160K *

Champion the migration to a modern Databricks lakehouse, designing robust data pipelines and ensuring data quality. Collaborate with teams to enhance analytics capabilities and set technical standards...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$102K - $127K *

Champion inventory planning and order management, leading a team to ensure accuracy and efficiency. Collaborate cross-functionally to align supply and demand while driving ERP/MRP improvements and mai...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Champion strategic growth by managing key accounts, fostering relationships, and driving sales initiatives. Collaborate with leadership to meet customer needs and exceed performance objectives while r...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$91K - $179K *

Join a team that's driving manufacturing transformation by aligning shop-floor operations with digital solutions. Collaborate with cross-functional teams to enhance production efficiency and quality a...

1 week ago

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Illinois?question toggle

    Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.

  • Are there high-paying jobs outside Chicago?question toggle

    Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.

  • How can I find Illinois jobs that pay $100,000 or more?question toggle

    Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.

  • Do Illinois job listings include remote or hybrid roles?question toggle

    Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.