Explore $100K+ Jobs in Illinois

Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.

Career Opportunities Across Illinois

Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.

Find a Role That Fits Your Experience

Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.

Advance Your Career in Illinois

Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.

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1,000+

Jobs in Illinois

Average Salary in USD

Average Salary: $117,822

Sort By: Relevance

$100K - $130K *

Elevate your career by delivering precise inventory reconciliations across departments, ensuring financial accuracy and audit readiness. Utilize advanced data platforms to enhance operational efficien...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$85K - $110K *

Champion innovative therapy practices and elevate patient care as you conduct evaluations and design personalized treatment plans in a supportive, growth-oriented environment. Join us to make a meanin...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$111K - $160K *

Transform category growth by leveraging insights and strategies to enhance customer performance. Collaborate cross-functionally to optimize assortments and drive sales initiatives across diverse retai...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$168K - $210K *

Lead digital manufacturing initiatives to enhance equipment performance and operational visibility. Drive strategic projects and support teams in troubleshooting to optimize plant reliability and sust...

6 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$110K - $170K *

Manage and oversee anatomic pathology operations, ensuring quality specimen processing, training staff, and leading quality improvement initiatives while maintaining accreditation readiness and optimi...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Lead groundbreaking research in AI safety and evaluation, bridging academic rigor with real-world challenges. Drive innovative methodologies and collaborate with top-tier institutions to enhance respo...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$88K - $100K *

Drive your career with a pivotal role in overseeing accounting operations, ensuring compliance with GAAP, and enhancing financial reporting accuracy while collaborating across teams to optimize proces...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$82K - $182K *

Accelerate privacy compliance and risk management across the organization, overseeing incident response and data governance initiatives while collaborating with cross-functional teams to implement eff...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$175K - $334K *

Elevate your career by leading a privacy legal team, providing strategic counsel on healthcare regulations, and balancing legal risks with business objectives while fostering strong internal relations...

Illinois, USRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$163K - $273K *

Shape the future of supply chain management by leading product domains, driving innovation, and fostering collaboration across teams to achieve strategic business outcomes and enhance customer experie...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$122K - $176K *

Empower patient access by leading reimbursement strategies and support initiatives. Collaborate with cross-functional teams to enhance customer experience and drive Dupixent pull-through efforts while...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$96K - $120K *

Pioneer growth and market penetration for advanced SPINNING Systems. Leverage technical expertise to support sales, engage customers, and collaborate cross-functionally, driving innovative solutions a...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$132K - $194K *

Elevate your career by leading global market strategies for innovative bioprocessing filtration products. Collaborate across teams to drive adoption and growth through compelling value propositions an...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$96K - $120K *

Champion the growth of SPINNING Systems by leveraging technical expertise, driving sales initiatives, and collaborating across teams to enhance customer engagement and market presence in the life scie...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$106K - $284K *

Lead product excellence by defining analytics initiatives, managing execution, and enhancing member experience through data-driven insights, collaboration, and innovation with cross-functional teams...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$103K - $172K *

Oversee and implement complex real estate projects, leading cross-functional teams to achieve facility solutions aligned with growth strategies while managing multiple large-scale projects within budg...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$126K - $164K *

Engineer powerful data pipelines and insights as a Senior Analytics Engineer, leading the transformation of enterprise data into AI-ready solutions by collaborating across multiple business domains to...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$95K - $140K *

Join a team that's dedicated to stabilizing complex IT incidents and enhancing system reliability. Leverage your expertise in server, network, and application support to mentor others and drive improv...

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $150K *

Champion valuation excellence by leading a team of appraisers in delivering accurate financial analytics and consulting for institutional properties, ensuring timely completion of assignments and adhe...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$118K - $219K *

Drive AI-driven content initiatives for case law, fostering innovation and accuracy while collaborating cross-functionally with product, tech, and data teams to enhance legal research capabilities and...

RemoteRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$83K - $222K *

Drive innovation by delivering high-quality web applications and interactive dashboards. Collaborate with cross-functional teams to integrate AI capabilities and build resilient APIs in a fast-paced...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$169K - $237K *

Champion the execution of a pivotal security initiative, collaborating across teams to enhance product resilience and security. Drive strategic direction, manage program transparency, and engage with...

6 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$96K - $128K *

Optimize organizational potential by driving strategic people initiatives, enhancing employee relations, and leading performance management processes to foster an inclusive and productive workplace en...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$107K - $204K *

Join a dynamic team as you manage complex government contracts, ensuring compliance and fostering strong relationships. Utilize your negotiation skills to support the P&C Mil Spares EPS aftermarket bu...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$150K - $180K *

Join a dynamic team to lead the development of innovative Microsoft-based platforms, driving modernization and AI integration while ensuring robust, scalable, and secure solutions in a highly regulate...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Illinois?question toggle

    Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.

  • Are there high-paying jobs outside Chicago?question toggle

    Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.

  • How can I find Illinois jobs that pay $100,000 or more?question toggle

    Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.

  • Do Illinois job listings include remote or hybrid roles?question toggle

    Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.